PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr4g081370.2

Common Name

MTR_4g081370

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

bHLH

Protein Properties

Length: 194aa MW: 21176.4 Da PI: 10.1272

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr4g081370.2	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	34	5.3e-11	36	83	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rE+ RRdr+N++f eL ++l + + K +Ka+iL Av+ + +L Medtr4g081370.2 36 SKACREKLRRDRLNDKFIELGSILEPG---RPAKTDKAAILIDAVRMVTQL 83 5678********************8...89************99988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	12.989	32	83	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	3.66E-13	32	102	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.59E-6	35	88	No hit	No description
Gene3D	G3DSA:4.10.280.10	7.1E-13	36	105	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.0E-8	36	83	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.5E-9	38	89	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 194 aa Download sequence Send to blast
MRMGAEVDGS LGDSDGLKES GSKKRVRSES CAATSSKACR EKLRRDRLND KFIELGSILE 60 PGRPAKTDKA AILIDAVRMV TQLRGEAQKL KDANSGLQEK IKELKVEKNE LRDEKQRLKA 120 EKEKLEQQLK SMNAPPSFLP TPTALPAAFA AQGQAHGNKL VPFISYPGVA MWQFMPPAAV 180 DTSQDHVLRP PVA*

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mtr.3417	0.0	flower\| glandular trichome\| leaf\| root

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Widely expressed throughout development, mostly in vasculatures. {ECO:0000269\|PubMed:17028341}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr4g081370.2

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT051569	0.0	BT051569.1 Medicago truncatula clone MTYF5_F6_F7_F81G-O-15 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003607701.1	1e-135	transcription factor ILR3
Swissprot	Q9FH37	1e-107	ILR3_ARATH; Transcription factor ILR3
TrEMBL	G7JF33	1e-138	G7JF33_MEDTR; BHLH domain class transcription factor
STRING	AES89899	1e-137	(Medicago truncatula)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	7e-85	bHLH family protein

Link Out ? help Back to Top
Phytozome	Medtr4g081370.2
Entrez Gene	11445675

Publications ? help Back to Top
Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]