PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr4g082580.1
Common NameMTR_4g082580
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family WRKY
Protein Properties Length: 389aa    MW: 42618.2 Da    PI: 8.355
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr4g082580.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY986e-31145202259
                      --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
             WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                      dDgynWrKYGqK+vkg efprsYY+Ct+++C v+kkver+  d++v+ i+Y+geH h+
  Medtr4g082580.1 145 DDGYNWRKYGQKQVKGCEFPRSYYKCTHPSCLVTKKVERDPVDGHVTAIIYKGEHIHQ 202
                      8********************************************************7 PP
2WRKY1061.9e-33278335259
                      --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
             WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                      +Dgy+WrKYGqK+vkg+++prsYY+Ct++gC+v+k+ver ++dpk+v +tYeg+Hnh+
  Medtr4g082580.1 278 EDGYRWRKYGQKVVKGNPYPRSYYKCTTPGCNVRKHVERVSTDPKAVLTTYEGKHNHD 335
                      8********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5081124.639139204IPR003657WRKY domain
Gene3DG3DSA:2.20.25.804.1E-27140204IPR003657WRKY domain
SuperFamilySSF1182902.35E-24144204IPR003657WRKY domain
SMARTSM007741.1E-32144203IPR003657WRKY domain
PfamPF031062.4E-23145202IPR003657WRKY domain
Gene3DG3DSA:2.20.25.806.8E-36263337IPR003657WRKY domain
SuperFamilySSF1182902.22E-29269337IPR003657WRKY domain
PROSITE profilePS5081137.86272337IPR003657WRKY domain
SMARTSM007744.8E-38277336IPR003657WRKY domain
PfamPF031061.9E-25278335IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 389 aa     Download sequence    Send to blast
MVGGGNGEWP SGGGFSPGPM TLLSNLFGDN DDCKSFSELL AGDTLDVEHG GGGGGGRGGG  60
GLSPLAMFTA PPQQTLAQAY SNAQNQSEHQ FSVSVVPTTT SLTQVPAITF NNIAQQLIPN  120
SVEYSSNSEQ RLQKSSFVNV DKANDDGYNW RKYGQKQVKG CEFPRSYYKC THPSCLVTKK  180
VERDPVDGHV TAIIYKGEHI HQRPRPSKLT NDNSSVQQVL SGTSDSEEEG DHETEVDYEP  240
GLKRRKTEAK LLNPALSHRT VSKPKIIVQT TSDVDLLEDG YRWRKYGQKV VKGNPYPRSY  300
YKCTTPGCNV RKHVERVSTD PKAVLTTYEG KHNHDVPAAK TNSHNLASNN SASQLKSQNA  360
IPEMQNFNRR GQHQPSAVAH LRLKEEHI*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A7e-42145338878Probable WRKY transcription factor 4
2lex_A7e-42145338878Probable WRKY transcription factor 4
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
15460GGRGGGG
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.118680.0root| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: In young, mature and senescent leaves. {ECO:0000269|PubMed:11722756}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Has a positive role in resistance to necrotrophic pathogens (e.g. Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e.g. Pseudomonas syringae). {ECO:0000269|PubMed:18570649, ECO:0000269|PubMed:22219184}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr4g082580.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By biotic and abiotic stresses such as pathogen infection (e.g. Botrytis cinerea and Pseudomonas syringae), salicylic acid (SA), jasmonic acid (JA), ethylene (ACC), liquid infiltration or spraying, and strongly during leaf senescence. {ECO:0000269|PubMed:11449049, ECO:0000269|PubMed:11722756, ECO:0000269|PubMed:18570649}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003607772.10.0probable WRKY transcription factor 3
SwissprotQ9XI901e-102WRKY4_ARATH; Probable WRKY transcription factor 4
TrEMBLG7JGC00.0G7JGC0_MEDTR; Putative transcription factor WRKY family
STRINGAES899690.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF154534100
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G13960.15e-97WRKY DNA-binding protein 4
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Aamir M, et al.
    Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach.
    Front Plant Sci, 2017. 8: p. 819
    [PMID:28611792]