PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr4g102530.2
Common NameMTR_4g102530
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family MIKC_MADS
Protein Properties Length: 206aa    MW: 23786.4 Da    PI: 9.2796
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr4g102530.2genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF1008.9e-32959151
                     S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
           SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
                     krien+snrqvtfskRrng+lKKA+ELSvLCdaeva+i+fs+tgklye+ss
  Medtr4g102530.2  9 KRIENESNRQVTFSKRRNGLLKKAFELSVLCDAEVALIVFSTTGKLYEFSS 59
                     79***********************************************96 PP
2K-box676.6e-23861701397
            K-box  13 kaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkk 97 
                      ++++l++      k++e L+ ++R+llGe+L+s+ + eLqq+e+qLe+sl+kiR++Kn+ll+eqie+l+ ke+ l eenk+L k+
  Medtr4g102530.2  86 NTQHLKECDIDTTKKLEHLELSKRKLLGEELGSCAFDELQQIENQLERSLSKIRARKNQLLKEQIEKLKDKERLLLEENKRLCKQ 170
                      4555555555567899*****************************************************************9887 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5006632.31161IPR002100Transcription factor, MADS-box
SMARTSM004325.7E-41160IPR002100Transcription factor, MADS-box
CDDcd002653.14E-40370No hitNo description
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
SuperFamilySSF554558.63E-33373IPR002100Transcription factor, MADS-box
PRINTSPR004041.7E-31323IPR002100Transcription factor, MADS-box
PfamPF003199.6E-281057IPR002100Transcription factor, MADS-box
PRINTSPR004041.7E-312338IPR002100Transcription factor, MADS-box
PRINTSPR004041.7E-313859IPR002100Transcription factor, MADS-box
PROSITE profilePS5129715.26987177IPR002487Transcription factor, K-box
PfamPF014861.1E-2388171IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 206 aa     Download sequence    Send to blast
MVRGKTQMKR IENESNRQVT FSKRRNGLLK KAFELSVLCD AEVALIVFST TGKLYEFSSS  60
SISKTVERYQ GKVKELVLST KGIQENTQHL KECDIDTTKK LEHLELSKRK LLGEELGSCA  120
FDELQQIENQ LERSLSKIRA RKNQLLKEQI EKLKDKERLL LEENKRLCKQ CGIGQNDCLN  180
KQQESVHDEE VETELFIGRP KKRMN*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5f28_A4e-21169169MEF2C
5f28_B4e-21169169MEF2C
5f28_C4e-21169169MEF2C
5f28_D4e-21169169MEF2C
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.54290.0leaf| root
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Mostly expressed in the outer layers of the root meristem (lateral root cap and epidermis) and in the central cylinder cells of mature roots. Also present in rosette leaves and seedlings and, to a lesser extent, in cauline leaves and flowers. Enriched in apices including the shoot apical meristem and developing leaf primordia. {ECO:0000269|PubMed:11115127, ECO:0000269|PubMed:12837945, ECO:0000269|PubMed:12949148, ECO:0000269|PubMed:16778081}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor that promotes flowering, especially in response to vernalization by short periods of cold, in an FLC-inpedendent manner. {ECO:0000269|PubMed:16778081}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr4g102530.2
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Maintained at very low levels by the polycomb-group (PcG) proteins MSI1, CLF, and EMF2 via histone methylation (H3K27me3). Derepressed upon cold treatment (vernalization). {ECO:0000269|PubMed:16778081}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHQ7380560.0HQ738056.1 Medicago truncatula isolate L0482C Soc1b gene, partial sequence.
GenBankHQ7380660.0HQ738066.1 Medicago truncatula isolate L0738D Soc1b gene, partial sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013457660.11e-144agamous-like MADS-box protein AGL19 isoform X1
RefseqXP_024638693.11e-144agamous-like MADS-box protein AGL19 isoform X1
SwissprotO827438e-73AGL19_ARATH; Agamous-like MADS-box protein AGL19
TrEMBLA0A072UQQ31e-143A0A072UQQ3_MEDTR; MADS-box transcription factor
STRINGXP_004515788.11e-104(Cicer arietinum)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G22950.11e-65AGAMOUS-like 19
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  3. Suter L,Rüegg M,Zemp N,Hennig L,Widmer A
    Gene regulatory variation mediates flowering responses to vernalization along an altitudinal gradient in Arabidopsis.
    Plant Physiol., 2014. 166(4): p. 1928-42
    [PMID:25339407]