PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr4g127040.1

Common Name

MTR_4g127040

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

WRKY

Protein Properties

Length: 318aa MW: 34870.5 Da PI: 10.4532

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr4g127040.1	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	98.9	3.3e-31	245	303	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 +D+++WrKYGqK++kgs++pr+YY+C+s gCp++k+ver+++dp+++++tYegeH+h Medtr4g127040.1 245 SDEFSWRKYGQKPIKGSPYPRGYYKCSSFkGCPARKHVERAQDDPNMLVVTYEGEHRHA 303 69**********************9877**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF10533	7.8E-18	199	242	IPR018872	Zn-cluster domain
Gene3D	G3DSA:2.20.25.80	9.0E-33	232	304	IPR003657	WRKY domain
PROSITE profile	PS50811	30.205	239	305	IPR003657	WRKY domain
SuperFamily	SSF118290	2.22E-26	242	303	IPR003657	WRKY domain
SMART	SM00774	4.4E-38	244	304	IPR003657	WRKY domain
Pfam	PF03106	3.6E-27	246	302	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 318 aa Download sequence Send to blast
MVVDPVVIPK LRMDEQRAIQ EAASAGLKSM EQLIRVLSSQ TSSSSSSSNQ LNQLDLVNKL 60 DCTEITDFTV SKFKTVINLL NRTGHARFRR APSSPPCSSY QFQSQSQPEK FKTQPQSTTL 120 DFAKPIQLVK SNPNPNLKPK TNQSTDLSVS QYSKSKEAYS ISTTTSSFMS TITGDGSVSD 180 GKIGPIISSG KPPLASSHRK RCHEATISGK VSSSGHCHCS KRRKSRVKRT IRVPAISSKV 240 ADIPSDEFSW RKYGQKPIKG SPYPRGYYKC SSFKGCPARK HVERAQDDPN MLVVTYEGEH 300 RHAQTVVTGA GFISQPL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	2e-21	232	302	2	71	WRKY transcription factor 1
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mtr.4433	0.0	leaf\| root\| stem

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: In young, mature and senescent leaves. {ECO:0000269\|PubMed:11722756}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Regulates rhizobacterium B.cereus AR156-induced systemic resistance (ISR) to P.syringae pv. tomato DC3000, probably by activating the jasmonic acid (JA)- signaling pathway (PubMed:26433201). {ECO:0000250, ECO:0000269\|PubMed:26433201}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr4g127040.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Strongly during leaf senescence (PubMed:11722756). Repressed by rhizobacterium B.cereus AR156 in leaves, and to a lower extent, by P.fluorescens WCS417r (PubMed:26433201). {ECO:0000269\|PubMed:11722756, ECO:0000269\|PubMed:26433201}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	EU526033	0.0	EU526033.1 Medicago truncatula WRKY transcription factor WRKY100577 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003610020.1	0.0	probable WRKY transcription factor 11
Swissprot	Q9SV15	1e-108	WRK11_ARATH; Probable WRKY transcription factor 11
TrEMBL	B3U396	0.0	B3U396_MEDTR; Putative transcription factor WRKY family
STRING	AES92217	0.0	(Medicago truncatula)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1314	34	98

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G31550.1	1e-102	WRKY DNA-binding protein 11

Link Out ? help Back to Top
Phytozome	Medtr4g127040.1
Entrez Gene	11424670

Publications ? help Back to Top
Haas BJ, et al. Full-length messenger RNA sequences greatly improve genome annotation. Genome Biol., 2002. 3(6): p. RESEARCH0029 [PMID:12093376] Naoumkina MA,He X,Dixon RA Elicitor-induced transcription factors for metabolic reprogramming of secondary metabolism in Medicago truncatula. BMC Plant Biol., 2008. 8: p. 132 [PMID:19102779] Brand LH,Kirchler T,Hummel S,Chaban C,Wanke D DPI-ELISA: a fast and versatile method to specify the binding of plant transcription factors to DNA in vitro. Plant Methods, 2010. 6: p. 25 [PMID:21108821] Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Brand LH, et al. Screening for protein-DNA interactions by automatable DNA-protein interaction ELISA. PLoS ONE, 2013. 8(10): p. e75177 [PMID:24146751] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Ali MA,Wieczorek K,Kreil DP,Bohlmann H The beet cyst nematode Heterodera schachtii modulates the expression of WRKY transcription factors in syncytia to favour its development in Arabidopsis roots. PLoS ONE, 2014. 9(7): p. e102360 [PMID:25033038] Jiang CH, et al. Transcription factors WRKY70 and WRKY11 served as regulators in rhizobacterium Bacillus cereus AR156-induced systemic resistance to Pseudomonas syringae pv. tomato DC3000 in Arabidopsis. J. Exp. Bot., 2016. 67(1): p. 157-74 [PMID:26433201] Ali MA, et al. Transcription factors WRKY11 and WRKY17 are involved in abiotic stress responses in Arabidopsis. J. Plant Physiol., 2018. 226: p. 12-21 [PMID:29689430]