PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr8g100050.2
Common NameMTR_8g100050
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family ARF
Protein Properties Length: 728aa    MW: 81045.1 Da    PI: 7.4192
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr8g100050.2genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B376.14e-24162263199
                      EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSS CS
               B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrs 88 
                      f+k+lt sd++++g +++ +++a+e+      + k++ +++l+ +d++g++W++++i+r++++r++l++GW+ Fv++++L +gD ++F   + +
  Medtr8g100050.2 162 FCKTLTASDTSTHGGFSVLRRHADEClppldmS-KQPPTQELVAKDLHGNEWRFRHIFRGQPRRHLLQSGWSVFVSSKRLVAGDAFIFL--RGE 252
                      99*****************************63.4445569************************************************..449 PP

                      EE..EEEEE-S CS
               B3  89 efelvvkvfrk 99 
                      ++el+v+v+r+
  Medtr8g100050.2 253 NGELRVGVRRA 263
                      999*****996 PP
2Auxin_resp117.98.5e-39288370183
       Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                      a+ha+ t+++F+v+Y+Pr+s++eF+v++++++++lk+++++GmRfkm+fe+e+++e+r++Gt+vg++d+d+ rWp SkWr+Lk
  Medtr8g100050.2 288 AWHAVLTGTMFTVYYKPRTSPAEFIVPYDQYMESLKNNYTIGMRFKMRFEGEEAPEQRFTGTIVGIEDSDSKRWPTSKWRCLK 370
                      79*******************************************************************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.108.0E-42158277IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019361.06E-40158291IPR015300DNA-binding pseudobarrel domain
CDDcd100175.60E-22160262No hitNo description
PfamPF023624.5E-22162263IPR003340B3 DNA binding domain
SMARTSM010191.8E-23162264IPR003340B3 DNA binding domain
PROSITE profilePS5086312.026162264IPR003340B3 DNA binding domain
PfamPF065072.1E-36288370IPR010525Auxin response factor
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008285Biological Processnegative regulation of cell proliferation
GO:0009734Biological Processauxin-activated signaling pathway
GO:0009737Biological Processresponse to abscisic acid
GO:0009911Biological Processpositive regulation of flower development
GO:0010047Biological Processfruit dehiscence
GO:0010150Biological Processleaf senescence
GO:0010227Biological Processfloral organ abscission
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0048481Biological Processplant ovule development
GO:0005634Cellular Componentnucleus
GO:0005515Molecular Functionprotein binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 728 aa     Download sequence    Send to blast
MFGMRDLEEE RNMASSEVSM KGNSVNGKGE NNVDGVGDAQ NGSSSSSTGR EAEAALYREL  60
WHACAGPLVT VPREGELVFY FPQGHIEQVE ASTNQASEQH MPVYDLRPKI LCRVINVMLK  120
AEPDTDEVFA QVTLVPEPNQ DENAVEKEAP PAPPPRFHVH SFCKTLTASD TSTHGGFSVL  180
RRHADECLPP LDMSKQPPTQ ELVAKDLHGN EWRFRHIFRG QPRRHLLQSG WSVFVSSKRL  240
VAGDAFIFLR GENGELRVGV RRAMRQQGNV PSSVISSHSM HLGVLATAWH AVLTGTMFTV  300
YYKPRTSPAE FIVPYDQYME SLKNNYTIGM RFKMRFEGEE APEQRFTGTI VGIEDSDSKR  360
WPTSKWRCLK VRWDETSNIP RPERVSPWKI EPALAPPALN PLPMPRPKRP RANVVPSSPD  420
SSVLTREASS KVSMDPLPTS GFQRVLQGQE SSTLRGNLAE SNDSYTAEKS VAWTPATDEE  480
KMDAVSTSRR YGSENWMPMS RQEPTYSDLL SGFGSTREGK HNMLTQWPVM PPGLSLNFLH  540
SNMKGSAQGS DNATYQAQGN MRYSAFGDYS VLHGHKVENP HGNFLMPPPP PTQYESPHSR  600
ELSQKQMSAK ISEAAKPKDS DCKLFGFSLL SSPTMLEPSL SQRNATSETS SHMQISSQHH  660
TFENDQKSEH SKSSKPADKL VIVDEHEKQL QTSQPHVKDV QLKPQSGSAR SCTKVSICIV  720
IVTFLTK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-179393922354Auxin response factor 1
4ldw_A1e-179393922354Auxin response factor 1
4ldw_B1e-179393922354Auxin response factor 1
4ldx_A1e-179393922354Auxin response factor 1
4ldx_B1e-179393922354Auxin response factor 1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.132100.0flower| glandular trichome| leaf| pod| root| stem
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expression increases during floral development. Expressed during ovary development with the highest expression on the third day after the flower fully opened. {ECO:0000269|PubMed:21735233}.
UniprotTISSUE SPECIFICITY: Expressed in root, leaf and stem (PubMed:26716451, PubMed:21735233). Also expressed in flower and fruit (PubMed:26716451). Expressed in flower buds about three days before opening including stamen, petal and sepal with the highest in ovary (PubMed:21735233). {ECO:0000269|PubMed:21735233, ECO:0000269|PubMed:26716451}.
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that binds specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs) (By similarity). Could act as transcriptional activator or repressor. Involved in the control of fruit ripening process. Regulates expression of a number of ripening regulators, transcription factors, and ethylene biosynthesis and signaling components (PubMed:26716451, PubMed:26959229). May act as a transcriptional repressor of auxin-responsive genes (PubMed:26716451). {ECO:0000255|RuleBase:RU004561, ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00574DAPTransfer from AT5G62000Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr8g100050.2
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By tomato fruit ripening. Expression is up-regulated by plant hormone auxin in tomato fruits. {ECO:0000269|PubMed:26716451}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1267940.0AC126794.15 Medicago truncatula chromosome 4 clone mth2-24j7, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003630583.20.0auxin response factor 2B
SwissprotK4DF010.0ARF2B_SOLLC; Auxin response factor 2B
TrEMBLG7LIT30.0G7LIT3_MEDTR; Auxin response factor
STRINGAET050590.0(Medicago truncatula)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62000.30.0auxin response factor 2
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  3. Breitel DA, et al.
    AUXIN RESPONSE FACTOR 2 Intersects Hormonal Signals in the Regulation of Tomato Fruit Ripening.
    PLoS Genet., 2016. 12(3): p. e1005903
    [PMID:26959229]