PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Migut.H00971.1.p

Organism

Mimulus guttatus

Taxonomic ID

4155

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe

Family

E2F/DP

Protein Properties

Length: 124aa MW: 13730.8 Da PI: 9.74

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Migut.H00971.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	30.7	5.3e-10	9	53	1	39
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse......dv 39 rkeksL+lltq+f+kl+ +++ + ++l+++ak L+ + + Migut.H00971.1.p 9 RKEKSLGLLTQNFVKLFLCTDMDLISLEDAAKLLLGDgkhtsmTT 53 79********************************99988775533 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	9.8E-7	6	43	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	0.0046	9	91	IPR003316	E2F/DP family, winged-helix DNA-binding domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 124 aa Download sequence Send to blast
MASKYGENRK EKSLGLLTQN FVKLFLCTDM DLISLEDAAK LLLGDGKHTS MTTRTKRFKV 60 DEDGLQILKP VNLMRVKNET ENEDDRTTTM GAKSYQFGPF APANVPQVGV SNDYKGKQVV 120 KKG*

Functional Description ? help Back to Top
Source	Description
UniProt	Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11867638, ECO:0000269\|PubMed:15649366, ECO:0000269\|PubMed:18787127}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Migut.H00971.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012837794.1	3e-40	PREDICTED: E2F transcription factor-like E2FE isoform X3
Refseq	XP_012846959.1	6e-40	PREDICTED: E2F transcription factor-like E2FE isoform X1
Refseq	XP_012846960.1	5e-40	PREDICTED: E2F transcription factor-like E2FE isoform X2
Refseq	XP_012846961.1	2e-40	PREDICTED: E2F transcription factor-like E2FE isoform X3
Swissprot	Q8LSZ4	2e-14	E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBL	A0A022QN48	2e-38	A0A022QN48_ERYGU; Uncharacterized protein (Fragment)
TrEMBL	A0A022RAA4	1e-38	A0A022RAA4_ERYGU; Uncharacterized protein (Fragment)
TrEMBL	A0A022RPY3	1e-37	A0A022RPY3_ERYGU; Uncharacterized protein
STRING	Migut.H00971.1.p	4e-86	(Erythranthe guttata)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G48160.2	5e-16	DP-E2F-like 1

Link Out ? help Back to Top
Phytozome	Migut.H00971.1.p

Publications ? help Back to Top
Chandran D, et al. Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid. Cell Host Microbe, 2014. 15(4): p. 506-13 [PMID:24721578] Wang Z, et al. Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis. PLoS ONE, 2016. 11(8): p. e0160684 [PMID:27505251] Heyman J,Polyn S,Eekhout T,De Veylder L Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1. Plant Physiol., 2017. 175(1): p. 303-313 [PMID:28698355]