PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Migut.H01974.1.p

Common Name

LOC105970409, MIMGU_mgv1a006727mg

Organism

Mimulus guttatus

Taxonomic ID

4155

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe

Family

TCP

Protein Properties

Length: 434aa MW: 47640.2 Da PI: 6.5602

Description

TCP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Migut.H01974.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	TCP	120.6	1.8e-37	45	183	3	132
TCP 3 gkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgt..............ssssasec.eaessss 80 g+kdrhsk++T++g+RdRRvRl a++a++f+d+qd+LG+d++sk+++WL+++ak ai+el+++ + + +++ Migut.H01974.1.p 45 GRKDRHSKVCTAKGPRDRRVRLAAHTAIQFYDVQDRLGYDRPSKAVDWLIKKAKSAIDELAQLpawhptatcpppppL----NPSfRPDDAAA 133 89*************************************************************777776655433320....22233333333 PP TCP 81 sasnsssgkaaksaa.kskksqksaasalnlakesrakarararertrekmri 132 +++n+++++++++++ +++s k+a + +e+ ++++++ r r++ ++ Migut.H01974.1.p 134 QHKNEHEEEEEEEENhRQSDSGKRA---MVMLQEEEEEEQEQDRRRQQALHHH 183 3332222222222221222222222...3333333333333333333333332 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF03634	4.4E-33	45	184	IPR005333	Transcription factor, TCP
PROSITE profile	PS51369	33.165	46	104	IPR017887	Transcription factor TCP subgroup

Sequence ? help Back to Top
Protein Sequence Length: 434 aa Download sequence Send to blast
MGGGDGSSSH HHQPTPSRLG LRSAAGAAVG EIVEVQGGHI VRSIGRKDRH SKVCTAKGPR 60 DRRVRLAAHT AIQFYDVQDR LGYDRPSKAV DWLIKKAKSA IDELAQLPAW HPTATCPPPP 120 PLNPSFRPDD AAAQHKNEHE EEEEEEENHR QSDSGKRAMV MLQEEEEEEQ EQDRRRQQAL 180 HHHNNSNPPQ ISSFLPPSMD SDVIADTIKS FFPMGASGES NSSGMQFHQP DNNQDLRLSL 240 QSFQDPIMLH HHHHRHHQTL THHHHNNEQS PPRGGQVLLS GIPLAFDGTP PWPDHHQFQR 300 LPPWNPAADA ATAGGGVGGG NMFNSPPPVP QQPLLQQLLG HNQFFQQQQQ RGPLQSSNTP 360 SIRAWIDPST MSDHNSGFIP IYPSSLSGIG FSGGFPGGFP GGGFHIPARI QGDEEEHDGY 420 SDKPSSASSD SRH*

Sequence ? help Back to Top

Protein Sequence Length: 434 aa Download sequence Send to blast

MGGGDGSSSH HHQPTPSRLG LRSAAGAAVG EIVEVQGGHI VRSIGRKDRH SKVCTAKGPR  60
DRRVRLAAHT AIQFYDVQDR LGYDRPSKAV DWLIKKAKSA IDELAQLPAW HPTATCPPPP  120
PLNPSFRPDD AAAQHKNEHE EEEEEEENHR QSDSGKRAMV MLQEEEEEEQ EQDRRRQQAL  180
HHHNNSNPPQ ISSFLPPSMD SDVIADTIKS FFPMGASGES NSSGMQFHQP DNNQDLRLSL  240
QSFQDPIMLH HHHHRHHQTL THHHHNNEQS PPRGGQVLLS GIPLAFDGTP PWPDHHQFQR  300
LPPWNPAADA ATAGGGVGGG NMFNSPPPVP QQPLLQQLLG HNQFFQQQQQ RGPLQSSNTP  360
SIRAWIDPST MSDHNSGFIP IYPSSLSGIG FSGGFPGGFP GGGFHIPARI QGDEEEHDGY  420
SDKPSSASSD SRH*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5zkt_A	2e-20	51	104	1	54	Putative transcription factor PCF6
5zkt_B	2e-20	51	104	1	54	Putative transcription factor PCF6
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor playing a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164) (PubMed:12931144, PubMed:17307931). Required during early steps of embryogenesis (PubMed:15634699). Participates in ovule develpment (PubMed:25378179). Activates LOX2 expression by binding to the 5'-GGACCA-3' motif found in its promoter (PubMed:18816164). {ECO:0000269\|PubMed:12931144, ECO:0000269\|PubMed:15634699, ECO:0000269\|PubMed:17307931, ECO:0000269\|PubMed:18816164, ECO:0000269\|PubMed:25378179}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Migut.H01974.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by the miRNA miR-JAW/miR319 (PubMed:12931144, PubMed:18816164). {ECO:0000269\|PubMed:12931144, ECO:0000269\|PubMed:18816164}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AM468863	1e-73	AM468863.2 Vitis vinifera contig VV78X023076.3, whole genome shotgun sequence.
GenBank	FQ381831	1e-73	FQ381831.1 Vitis vinifera clone SS0ABG82YF20.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012850679.1	0.0	PREDICTED: transcription factor TCP4-like
Swissprot	Q8LPR5	4e-83	TCP4_ARATH; Transcription factor TCP4
TrEMBL	A0A022QIJ2	0.0	A0A022QIJ2_ERYGU; Uncharacterized protein
STRING	Migut.H01974.1.p	0.0	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA3207	23	49

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G15030.3	1e-37	TCP family protein

Link Out ? help Back to Top
Phytozome	Migut.H01974.1.p
Entrez Gene	105970409

Publications ? help Back to Top
Schommer C, et al. Control of jasmonate biosynthesis and senescence by miR319 targets. PLoS Biol., 2008. 6(9): p. e230 [PMID:18816164] Ju Y, et al. Arabidopsis JINGUBANG Is a Negative Regulator of Pollen Germination That Prevents Pollination in Moist Environments. Plant Cell, 2016. 28(9): p. 2131-2146 [PMID:27468890] Challa KR,Aggarwal P,Nath U Activation of YUCCA5 by the Transcription Factor TCP4 Integrates Developmental and Environmental Signals to Promote Hypocotyl Elongation in Arabidopsis. Plant Cell, 2016. 28(9): p. 2117-2130 [PMID:27597774] Alvarez JP,Furumizu C,Efroni I,Eshed Y,Bowman JL Active suppression of a leaf meristem orchestrates determinate leaf growth. Elife, 2017. [PMID:27710768] Li J, et al. RABBIT EARS regulates the transcription of TCP4 during petal development in Arabidopsis. J. Exp. Bot., 2016. 67(22): p. 6473-6480 [PMID:27838638] Sun X, et al. Activation of secondary cell wall biosynthesis by miR319-targeted TCP4 transcription factor. Plant Biotechnol. J., 2017. 15(10): p. 1284-1294 [PMID:28233945] Kubota A, et al. TCP4-dependent induction of CONSTANS transcription requires GIGANTEA in photoperiodic flowering in Arabidopsis. PLoS Genet., 2017. 13(6): p. e1006856 [PMID:28628608] Koyama T,Sato F,Ohme-Takagi M Roles of miR319 and TCP Transcription Factors in Leaf Development. Plant Physiol., 2017. 175(2): p. 874-885 [PMID:28842549] Bresso EG,Chorostecki U,Rodriguez RE,Palatnik JF,Schommer C Spatial Control of Gene Expression by miR319-Regulated TCP Transcription Factors in Leaf Development. Plant Physiol., 2018. 176(2): p. 1694-1708 [PMID:29133375] Vadde BVL,Challa KR,Nath U The TCP4 transcription factor regulates trichome cell differentiation by directly activating GLABROUS INFLORESCENCE STEMS in Arabidopsis thaliana. Plant J., 2018. 93(2): p. 259-269 [PMID:29165850] Challa KR,Rath M,Nath U The CIN-TCP transcription factors promote commitment to differentiation in Arabidopsis leaf pavement cells via both auxin-dependent and independent pathways. PLoS Genet., 2019. 15(2): p. e1007988 [PMID:30742619]