PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID NNU_007305-RA
Organism
Nelumbo nucifera
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo
Family C2H2
Protein Properties Length: 534aa    MW: 58773.5 Da    PI: 6.1357
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
NNU_007305-RAgenomeCASView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H219.42.8e-06280301223
                    EETTTTEEESSHHHHHHHHHHT CS
        zf-C2H2   2 kCpdCgksFsrksnLkrHirtH 23 
                     C +Cgk F+r  nL+ H+r H
  NNU_007305-RA 280 FCMICGKGFKRDANLRMHMRGH 301
                    59******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576675.45E-5277304No hitNo description
SMARTSM003550.0057279301IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.697279306IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.5E-5280330IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280281301IPR007087Zinc finger, C2H2
SMARTSM0035556328361IPR015880Zinc finger, C2H2-like
SMARTSM0035521366388IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010044Biological Processresponse to aluminum ion
GO:0010447Biological Processresponse to acidic pH
GO:0005634Cellular Componentnucleus
GO:0003676Molecular Functionnucleic acid binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 534 aa     Download sequence    Send to blast
MDLKGRRCSE AWPKSRLGND SLKTLTLDLE PFNQFNSLQQ NQKWNGPDNF DYGYRIATSY  60
SEVNPLPAPL SSNPDNQIKT PSQVDKQTIE ALISASKLQD WDPRTMLSNL SFLEQKIHQL  120
QDLVHLIVGR EGRAVGRPDE IEAQQQQLVT ADLTSIIVQL ISTAGSLLPS VKNTLAANPF  180
VGQLGSSSGV GFPHILDAND AMQQDNGGSK VSDHSDQIEP PSNCRHEQNN GGQSNPLVST  240
IEEHDPKDEE DAGEGENLPP GSYEVLQLEK EEILAPHTHF CMICGKGFKR DANLRMHMRG  300
HGDEYKTPAA LAKPQKESNS EPMLIKRYSC PFAGCKRNKD HKKFQPLKTI LCVKNHYKRT  360
HCDKSYTCSR CNSKKFSVIA DLKTHEKHCG RDKWLCSCGT TFSRKDKLFG HIALFQGHTP  420
ALPPEENKVS SGASDLGGSS EVTETTQVEP TGFNFSSGTS NVGSIQDDVD MKGNVDDPTG  480
YFSPLNFDTC NFGGFHEFPR PPFEVSDSSF AFLLSGSCNY ISKTGGASGS DALE
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269|PubMed:17535918, ECO:0000269|PubMed:18826429, ECO:0000269|PubMed:19321711, ECO:0000269|PubMed:23935008}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00196ampDAPTransfer from AT1G34370Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269|PubMed:17535918}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010256329.10.0PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1
RefseqXP_010256330.10.0PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1
SwissprotQ9C8N50.0STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBLA0A1U7ZVU20.0A0A1U7ZVU2_NELNU; protein SENSITIVE TO PROTON RHIZOTOXICITY 1
STRINGXP_010256329.10.0(Nelumbo nucifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G34370.20.0C2H2 family protein
Publications ? help Back to Top
  1. Kobayashi Y, et al.
    Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions.
    Plant Physiol., 2013. 163(1): p. 180-92
    [PMID:23839867]
  2. Yokosho K,Yamaji N,Ma JF
    Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench).
    Plant Cell Physiol., 2014. 55(12): p. 2077-91
    [PMID:25273892]
  3. Geng X, et al.
    LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis.
    Plant J., 2017. 90(3): p. 491-504
    [PMID:28181322]
  4. Balzergue C, et al.
    Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation.
    Nat Commun, 2017. 8: p. 15300
    [PMID:28504266]
  5. Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A
    Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation.
    Front Plant Sci, 2017. 8: p. 822
    [PMID:28567051]
  6. Jiang F, et al.
    Identification and characterization of suppressor mutants of stop1.
    BMC Plant Biol., 2017. 17(1): p. 128
    [PMID:28738784]
  7. Daspute AA, et al.
    Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms.
    Front Plant Sci, 2017. 8: p. 1358
    [PMID:28848571]
  8. Sharma A,Wai CM,Ming R,Yu Q
    Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis.
    Genome Biol Evol, 2017. 9(9): p. 2170-2190
    [PMID:28922793]
  9. Zhang Y, et al.
    The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis.
    Front Plant Sci, 2018. 9: p. 118
    [PMID:29491872]