PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID NNU_010178-RA
Organism
Nelumbo nucifera
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo
Family C2H2
Protein Properties Length: 318aa    MW: 37269.6 Da    PI: 6.8385
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
NNU_010178-RAgenomeCASView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2120.00065106128123
                    EEETTTTEEESSHHHHHHHHHHT CS
        zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                    + C+ C    +rk++L+rH+r++
  NNU_010178-RA 106 FFCEFCLNFMKRKEQLQRHMRKC 128
                    67*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541605.77E-5173IPR016197Chromo domain-like
PROSITE profilePS5172656.94672313IPR002717Histone acetyltransferase domain, MYST-type
SuperFamilySSF557291.48E-8773314IPR016181Acyl-CoA N-acyltransferase
Gene3DG3DSA:3.30.60.605.1E-2577129No hitNo description
Gene3DG3DSA:3.40.630.306.3E-34131202IPR016181Acyl-CoA N-acyltransferase
PfamPF018531.3E-32133202IPR002717Histone acetyltransferase domain, MYST-type
PfamPF018533.7E-23203280IPR002717Histone acetyltransferase domain, MYST-type
Gene3DG3DSA:3.40.630.303.5E-13203244IPR016181Acyl-CoA N-acyltransferase
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0016747Molecular Functiontransferase activity, transferring acyl groups other than amino-acyl groups
Sequence ? help Back to Top
Protein Sequence    Length: 318 aa     Download sequence    Send to blast
NRRLDEWVKL EQLDLDSVET DVDEKVEDKL PKQTWSQRSG RDRWQNSYLS FIHIQGHEEL  60
DAASLREHEE FTKVKNIATI ELGRYEIETW YFSPFPPEYN DCSKLFFCEF CLNFMKRKEQ  120
LQRHMRKCDL KHPPGDEIYR NGTLSMFEVD GKKNKVYGQN LCYLAKLFLD HKTLYYDVDL  180
FLFYVLCECD DRGCHMVGYF SKVAYELSKK EGKVGTPERP LSDLGLVSYR GYWTRVLLDI  240
LKKHKGNISI KELSDMTAIK AEDILTTLQG LDLIQYRKGQ HVICADPKVL DRHLKAAGRG  300
GLEVDVSKLI WTPYKEQG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4dnc_A3e-92683171282Histone acetyltransferase KAT8
4dnc_B3e-92683171282Histone acetyltransferase KAT8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtHistone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:17877703, PubMed:19040736, PubMed:22170978, PubMed:23273925). Essential for gametophyte development (PubMed:19040736). Involved in DNA repair after UV-B exposure (PubMed:22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269|PubMed:17877703, ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:22170978, ECO:0000269|PubMed:23273925}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269|PubMed:22170978}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010261128.10.0PREDICTED: histone acetyltransferase of the MYST family 1-like isoform X1
SwissprotQ9FLF70.0MYST1_ARATH; Histone acetyltransferase of the MYST family 1
TrEMBLA0A1U8A2860.0A0A1U8A286_NELNU; Histone acetyltransferase
STRINGXP_010261128.10.0(Nelumbo nucifera)
Publications ? help Back to Top
  1. Latrasse D, et al.
    The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis.
    BMC Plant Biol., 2008. 8: p. 121
    [PMID:19040736]
  2. Campi M,D'Andrea L,Emiliani J,Casati P
    Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA.
    Plant Physiol., 2012. 158(2): p. 981-95
    [PMID:22170978]
  3. Bari A,Orazova S,Ivashchenko A
    miR156- and miR171-binding sites in the protein-coding sequences of several plant genes.
    Biomed Res Int, 2013. 2013: p. 307145
    [PMID:23936788]
  4. Xu Y, et al.
    Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.
    Nucleic Acids Res., 2014. 42(17): p. 10960-74
    [PMID:25183522]
  5. Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB
    3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana.
    J Mol Model, 2016. 22(11): p. 256
    [PMID:27709438]
  6. Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P
    HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1179
    [PMID:28740501]