PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID NNU_014544-RA
Organism
Nelumbo nucifera
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo
Family ARR-B
Protein Properties Length: 702aa    MW: 76205.9 Da    PI: 5.7413
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
NNU_014544-RAgenomeCASView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like91.38.6e-29213266155
        G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                    kpr++W+ eLH++Fv av+qL G++kA+Pk+ilelm+v+gLt+e+v+SHLQkYRl
  NNU_014544-RA 213 KPRVVWSVELHQQFVAAVNQL-GIDKAVPKKILELMNVPGLTRENVASHLQKYRL 266
                    79*******************.********************************8 PP
2Response_reg77.25.7e-26351431109
                    EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTTE CS
   Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaGa 94 
                    vl+vdD+p+ +++l ++l++  y ev+ +d +e al ll+e++  +D+++ D+ mp+mdG++ll++i  e  +lp+i+++a + ++ + + +  Ga
  NNU_014544-RA  35 VLVVDDDPTCLRILDKMLRNCLY-EVTICDRAEVALSLLRESKsgFDIVISDVHMPDMDGFKLLEHIGLEM-DLPVIMMSADDGKDVVMKGVTHGA 128
                    89*********************.***************999999**********************6654.8*********************** PP

                    SEEEESS--HHHHHH CS
   Response_reg  95 kdflsKpfdpeelvk 109
                     d+l Kp+ +e+l +
  NNU_014544-RA 129 CDYLIKPVRIEALKN 143
                    ***********9986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363922.0E-1721692IPR017053Response regulator B-type, plant
Gene3DG3DSA:3.40.50.23002.8E-4132175No hitNo description
SuperFamilySSF521727.83E-3532157IPR011006CheY-like superfamily
SMARTSM004485.2E-2933145IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011042.03534149IPR001789Signal transduction response regulator, receiver domain
PfamPF000729.0E-2335143IPR001789Signal transduction response regulator, receiver domain
CDDcd001564.36E-2736148No hitNo description
SuperFamilySSF466893.76E-20210270IPR009057Homeodomain-like
PROSITE profilePS5129411.048210269IPR017930Myb domain
Gene3DG3DSA:1.10.10.602.6E-30212271IPR009057Homeodomain-like
TIGRFAMsTIGR015571.0E-24213266IPR006447Myb domain, plants
PfamPF002491.0E-7215265IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009873Biological Processethylene-activated signaling pathway
GO:0010082Biological Processregulation of root meristem growth
GO:0010119Biological Processregulation of stomatal movement
GO:0010150Biological Processleaf senescence
GO:0071368Biological Processcellular response to cytokinin stimulus
GO:0080113Biological Processregulation of seed growth
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 702 aa     Download sequence    Send to blast
MNMDSGGGSV SLANSILTKK AADAISDQFP AGLRVLVVDD DPTCLRILDK MLRNCLYEVT  60
ICDRAEVALS LLRESKSGFD IVISDVHMPD MDGFKLLEHI GLEMDLPVIM MSADDGKDVV  120
MKGVTHGACD YLIKPVRIEA LKNIWQHVVR KRRNDLKELE QSGSMEDSDR HRKPSEDGDY  180
ASSVNDGNWR NSKRRKDEEE EGEERDDTST LKKPRVVWSV ELHQQFVAAV NQLGIDKAVP  240
KKILELMNVP GLTRENVASH LQKYRLYLRR LSGVSQHQNG LNTPFMGPQE ASFGPMSTLD  300
GLDLQALAVS GQLAPQSLAT LQAGGLGRST ANASISMPLV DQRNIFTSDA SKLRVGAGQQ  360
SVNSSSKQVN LIHGLPTNME PKQLSHLHQS VQSFGTMGLQ VSEGVSSFLN IPATSLRTSS  420
SHVDSVLGSQ NSSLMIQMAQ PQSRGHLLND ITGSHSSGLQ SSMVQQIFSN EIAGQVLGRN  480
GVILNGKGAA YNLVSQASPM ADFPLNHIAE LPGNGLPIGN TLTSSSTLTS TGMFQGGNVD  540
TKGPRGFAPV CDIFSEICQS KPQDWELQNV GLTFEASQPI TSVQGNVDLT QAVLGNQGFA  600
SSQKNLLNRN ASVVGKAVVP QRQENEHGKI EASVQRPINP LLNNSFRVKP ETISDFSCDN  660
LLIPQRYGQD DLMSALFKQQ EGTGSLESEC NFDGYTMDNI PV
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A2e-22212272464ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00054PBMTransfer from AT4G16110Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010268091.10.0PREDICTED: two-component response regulator ARR2-like isoform X2
SwissprotQ9ZWJ90.0ARR2_ARATH; Two-component response regulator ARR2
TrEMBLA0A1U8APJ30.0A0A1U8APJ3_NELNU; two-component response regulator ARR2-like isoform X2
STRINGXP_010268090.10.0(Nelumbo nucifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16110.11e-176response regulator 2
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  3. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  4. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  5. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  6. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  7. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  8. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  9. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]