PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

NNU_017667-RA

Organism

Nelumbo nucifera

Taxonomic ID

4432

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo

Family

EIL

Protein Properties

Length: 325aa MW: 36764.9 Da PI: 5.9273

Description

EIL family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
NNU_017667-RA	genome	CAS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	EIN3	29.2	1.6e-09	1	87	238	317
--SHHHHHHHHHHTTTTT-S--XXXX...XXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX....XXXXXXXXXXXXXXX CS EIN3 238 msakesfallsvlnqeekecatvsah...ssslrkqspkvtlsceqkedvegkkeskikhvqavktta....gfpvvrkrkkkpses 317 m++ke +++l+v+nqee+ ++++ + s s+++ s ++ +s+++++dveg +++ +vq++k ++ ++ + kr +++ NNU_017667-RA 1 MTSKEIATWLAVINQEEAFSNKLHLEsypSMSSTTTSGSFAISNNNEYDVEGVENNLNVEVQECKPHNvnlfNLGMGTKRAVEQGAA 87 89********************99653337778**************888888899999999888888444444444333322 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF13869	1.5E-55	106	240	IPR016706	Cleavage/polyadenylation specificity factor subunit 5
Gene3D	G3DSA:3.90.79.10	9.0E-4	137	194	IPR015797	NUDIX hydrolase domain-like
Pfam	PF13869	2.0E-19	265	318	IPR016706	Cleavage/polyadenylation specificity factor subunit 5

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006378	Biological Process	mRNA polyadenylation
GO:0005849	Cellular Component	mRNA cleavage factor complex
GO:0003729	Molecular Function	mRNA binding
GO:0016787	Molecular Function	hydrolase activity

Sequence ? help Back to Top
Protein Sequence Length: 325 aa Download sequence Send to blast
MTSKEIATWL AVINQEEAFS NKLHLESYPS MSSTTTSGSF AISNNNEYDV EGVENNLNVE 60 VQECKPHNVN LFNLGMGTKR AVEQGAAYTS EQADELRLTD MVNSSVVNTY PLSSYTFGTK 120 EPKMEKDTSV ADRLARMKVN YMKEGMRTSV EAILLVQEHN HPHILLLQIG NTFCKLPGGR 180 LKPGENEIEG LKRKLSSKLA ANSTALQPDW QIGECVAIWW RPNFETIMYP YCPPHITKPK 240 VNSLPNISDI GSFVDFAEPN DFLFQECKKL FLVHLSEREY FAVPKNLKLL AVPLFELYDN 300 VQRYGPVIST IPQQLSRFQF NMINA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3bap_A	7e-77	77	320	12	224	Cleavage and polyadenylation specificity factor subunit 5
3mdg_A	7e-77	77	320	12	224	Cleavage and polyadenylation specificity factor subunit 5
3mdg_B	7e-77	77	320	12	224	Cleavage and polyadenylation specificity factor subunit 5
3mdi_A	7e-77	77	320	12	224	Cleavage and polyadenylation specificity factor subunit 5
3mdi_B	7e-77	77	320	12	224	Cleavage and polyadenylation specificity factor subunit 5
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides. May have a role in mRNA export. {ECO:0000250\|UniProtKB:O43809}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010273110.1	1e-144	PREDICTED: pre-mRNA cleavage factor Im 25 kDa subunit 2
Swissprot	Q8GXS3	1e-128	CFIS2_ARATH; Pre-mRNA cleavage factor Im 25 kDa subunit 2
TrEMBL	A0A1U8B1N7	1e-142	A0A1U8B1N7_NELNU; pre-mRNA cleavage factor Im 25 kDa subunit 2
STRING	XP_010273110.1	1e-143	(Nelumbo nucifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G20770.1	5e-09	EIL family protein

Publications ? help Back to Top
Forbes KP,Addepalli B,Hunt AG An Arabidopsis Fip1 homolog interacts with RNA and provides conceptual links with a number of other polyadenylation factor subunits. J. Biol. Chem., 2006. 281(1): p. 176-86 [PMID:16282318] Hunt AG, et al. Arabidopsis mRNA polyadenylation machinery: comprehensive analysis of protein-protein interactions and gene expression profiling. BMC Genomics, 2008. 9: p. 220 [PMID:18479511]