PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

NNU_018448-RA

Organism

Nelumbo nucifera

Taxonomic ID

4432

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo

Family

GRAS

Protein Properties

Length: 499aa MW: 56052.4 Da PI: 5.1393

Description

GRAS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
NNU_018448-RA	genome	CAS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	GRAS	354.7	1.4e-108	119	498	3	374
GRAS 3 elLlecAeavssgdlelaqalLarlselaspdgdpmqRlaayfteALaarlarsvselykalppsetseknsseelaalklfsevsPilkfshlta 98 +lLle A+a+++++ +++q+l++ l+el+sp+gd+ q+la+yf++AL +r+++s++++y++l++ ++++ + +++ +++ f+evsP+ +f+h++ NNU_018448-RA 119 NLLLETARAIADNNSSRTQQLMWMLNELSSPYGDTDQKLASYFLQALFSRMTDSGERCYRTLASASEKTCSFDSTRKMVLKFQEVSPWTTFGHVAS 214 79**********************************************************8888876666666666666*********** PP GRAS 99 NqaIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgspesg........skeeleetgerLakfAeelgvpfefnvlvak.r 185 N aIlea++ge+++Hi+D++ ++++QWp+Ll+aLa+R++++p+lR+T+v +++++ ++ ++e+g+r++kfA+ +gvpf+fnv+++ + NNU_018448-RA 215 NGAILEAFDGESKLHIVDISNTYCTQWPTLLEALATRTDETPHLRLTTVMANRPSsssggiaaVQKVMKEIGNRMEKFARLMGVPFKFNVVHHVgD 310 *********************************************99887788999999999*********************96656 PP GRAS 186 ledleleeLrvkpgEalaVnlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadhnse....sFlerflealeyysalfdsleaklpr 277 l+dl+l eL+++ +EalaVn++ lh++ +++++rd +++++++l+Pk+v+vve ead++ + +F+++f e+l+++ + f+sl++++pr NNU_018448-RA 311 LSDLNLAELDIRDDEALAVNCIGTLHSVT----TVDNRRDIIISTFRRLRPKIVTVVEDEADLDVGadgfDFVKGFQESLRWFRVYFESLDESFPR 402 **************************8....88888999***************99854445679********************* PP GRAS 278 eseerikvErellgreivnvvacegaerrerhetlekWrerleeaGFkpvplsekaakqaklllrkvksdg.yrveeesgslvlgWkdrpLvsvSa 372 +s+e ++Er+ gr++v+++ac+ ae+ er+e++++W++rl++aGF+p ++s+++ +++++llr++ +g ++ +++ ++l Wk++p+v++Sa NNU_018448-RA 403 ASNECLMLERA-AGRSLVDLLACSPAESSERRESAARWSQRLHAAGFSPFAFSDDVSDDVRALLRRYR-EGwSMIPGSDAGIFLAWKEQPVVWASA 496 *******.****************************************************.55277789999999*********** PP GRAS 373 Wr 374 W+ NNU_018448-RA 497 WK 498 *8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50985	51.787	91	478	IPR005202	Transcription factor GRAS
Pfam	PF03514	4.8E-106	119	498	IPR005202	Transcription factor GRAS

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008356	Biological Process	asymmetric cell division
GO:0009956	Biological Process	radial pattern formation
GO:0045930	Biological Process	negative regulation of mitotic cell cycle
GO:0048366	Biological Process	leaf development
GO:0055072	Biological Process	iron ion homeostasis
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 499 aa Download sequence Send to blast
MDTLFRLVSL QSDQSINSSR TSSSSRSSRQ NHPYHQQEEE CGNFFMDEDD FSSSSKQFFP 60 YQQYHYPSTA TTSTPTTTTN TSTTTTHGFE PSHEFAFSSP CPDLNFEFAS TTSGKWASNL 120 LLETARAIAD NNSSRTQQLM WMLNELSSPY GDTDQKLASY FLQALFSRMT DSGERCYRTL 180 ASASEKTCSF DSTRKMVLKF QEVSPWTTFG HVASNGAILE AFDGESKLHI VDISNTYCTQ 240 WPTLLEALAT RTDETPHLRL TTVMANRPSS SSGGIAAVQK VMKEIGNRME KFARLMGVPF 300 KFNVVHHVGD LSDLNLAELD IRDDEALAVN CIGTLHSVTT VDNRRDIIIS TFRRLRPKIV 360 TVVEDEADLD VGADGFDFVK GFQESLRWFR VYFESLDESF PRASNECLML ERAAGRSLVD 420 LLACSPAESS ERRESAARWS QRLHAAGFSP FAFSDDVSDD VRALLRRYRE GWSMIPGSDA 480 GIFLAWKEQP VVWASAWKP

Sequence ? help Back to Top

Protein Sequence Length: 499 aa Download sequence Send to blast

MDTLFRLVSL QSDQSINSSR TSSSSRSSRQ NHPYHQQEEE CGNFFMDEDD FSSSSKQFFP  60
YQQYHYPSTA TTSTPTTTTN TSTTTTHGFE PSHEFAFSSP CPDLNFEFAS TTSGKWASNL  120
LLETARAIAD NNSSRTQQLM WMLNELSSPY GDTDQKLASY FLQALFSRMT DSGERCYRTL  180
ASASEKTCSF DSTRKMVLKF QEVSPWTTFG HVASNGAILE AFDGESKLHI VDISNTYCTQ  240
WPTLLEALAT RTDETPHLRL TTVMANRPSS SSGGIAAVQK VMKEIGNRME KFARLMGVPF  300
KFNVVHHVGD LSDLNLAELD IRDDEALAVN CIGTLHSVTT VDNRRDIIIS TFRRLRPKIV  360
TVVEDEADLD VGADGFDFVK GFQESLRWFR VYFESLDESF PRASNECLML ERAAGRSLVD  420
LLACSPAESS ERRESAARWS QRLHAAGFSP FAFSDDVSDD VRALLRRYRE GWSMIPGSDA  480
GIFLAWKEQP VVWASAWKP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_B	0.0	83	499	4	420	Protein SHORT-ROOT
5b3h_E	0.0	83	499	4	420	Protein SHORT-ROOT
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor required for quiescent center cells specification and maintenance of surrounding stem cells, and for the asymmetric cell division involved in radial pattern formation in roots. Essential for both cell division and cell specification. Regulates the radial organization of the shoot axial organs and is required for normal shoot gravitropism. Directly controls the transcription of SCR, and when associated with SCR, of MGP, RLK, TRI, NUC and SCL3. {ECO:0000269\|PubMed:10850497, ECO:0000269\|PubMed:12569126, ECO:0000269\|PubMed:15314023, ECO:0000269\|PubMed:16640459, ECO:0000269\|PubMed:17446396, ECO:0000269\|PubMed:9670559}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010274383.1	0.0	PREDICTED: protein SHORT-ROOT-like
Swissprot	Q9SZF7	0.0	SHR_ARATH; Protein SHORT-ROOT
TrEMBL	A0A1U8B0Y1	0.0	A0A1U8B0Y1_NELNU; protein SHORT-ROOT-like
STRING	XP_010274383.1	0.0	(Nelumbo nucifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G37650.1	0.0	GRAS family protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Muraro D, et al. Integration of hormonal signaling networks and mobile microRNAs is required for vascular patterning in Arabidopsis roots. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(2): p. 857-62 [PMID:24381155] Tian H,Jia Y,Niu T,Yu Q,Ding Z The key players of the primary root growth and development also function in lateral roots in Arabidopsis. Plant Cell Rep., 2014. 33(5): p. 745-53 [PMID:24504658] Gao X,Wang C,Cui H Identification of bundle sheath cell fate factors provides new tools for C3-to-C4 engineering. Plant Signal Behav, 2018. [PMID:24819776] Ahrazem O, et al. Ectopic expression of a stress-inducible glycosyltransferase from saffron enhances salt and oxidative stress tolerance in Arabidopsis while alters anchor root formation. Plant Sci., 2015. 234: p. 60-73 [PMID:25804810] Jia Y, et al. The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development. J. Exp. Bot., 2015. 66(15): p. 4631-42 [PMID:25998905] Zhang M, et al. A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis. Plant J., 2015. 83(4): p. 582-99 [PMID:26072661] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Miguel A,Milhinhos A,Novák O,Jones B,Miguel CM The SHORT-ROOT-like gene PtSHR2B is involved in Populus phellogen activity. J. Exp. Bot., 2016. 67(5): p. 1545-55 [PMID:26709311] Gong X, et al. SEUSS Integrates Gibberellin Signaling with Transcriptional Inputs from the SHR-SCR-SCL3 Module to Regulate Middle Cortex Formation in the Arabidopsis Root. Plant Physiol., 2016. 170(3): p. 1675-83 [PMID:26818732] Kim ES, et al. HAWAIIAN SKIRT regulates the quiescent center-independent meristem activity in Arabidopsis roots. Physiol Plant, 2016. 157(2): p. 221-33 [PMID:26968317] Lee SA, et al. Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue. Mol Plant, 2016. 9(6): p. 870-84 [PMID:26970019] Li Q,Zhao Y,Yue M,Xue Y,Bao S The Protein Arginine Methylase 5 (PRMT5/SKB1) Gene Is Required for the Maintenance of Root Stem Cells in Response to DNA Damage. J Genet Genomics, 2016. 43(4): p. 187-97 [PMID:27090604] Clark NM, et al. Tracking transcription factor mobility and interaction in Arabidopsis roots with fluorescence correlation spectroscopy. Elife, 2017. [PMID:27288545] Yoon EK, et al. Conservation and Diversification of the SHR-SCR-SCL23 Regulatory Network in the Development of the Functional Endodermis in Arabidopsis Shoots. Mol Plant, 2016. 9(8): p. 1197-1209 [PMID:27353361] Waszczak C, et al. SHORT-ROOT Deficiency Alleviates the Cell Death Phenotype of the Arabidopsis catalase2 Mutant under Photorespiration-Promoting Conditions. Plant Cell, 2016. 28(8): p. 1844-59 [PMID:27432873] Yu Q, et al. A P-Loop NTPase Regulates Quiescent Center Cell Division and Distal Stem Cell Identity through the Regulation of ROS Homeostasis in Arabidopsis Root. PLoS Genet., 2016. 12(9): p. e1006175 [PMID:27583367] Sparks EE, et al. Establishment of Expression in the SHORTROOT-SCARECROW Transcriptional Cascade through Opposing Activities of Both Activators and Repressors. Dev. Cell, 2016. 39(5): p. 585-596 [PMID:27923776] Hirano Y, et al. Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD. Nat Plants, 2017. 3: p. 17010 [PMID:28211915] Henry S, et al. SHR overexpression induces the formation of supernumerary cell layers with cortex cell identity in rice. Dev. Biol., 2017. 425(1): p. 1-7 [PMID:28263767] Möller BK, et al. Auxin response cell-autonomously controls ground tissue initiation in the early Arabidopsis embryo. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(12): p. E2533-E2539 [PMID:28265057] Kobayashi A,Miura S,Kozaki A INDETERMINATE DOMAIN PROTEIN binding sequences in the 5'-untranslated region and promoter of the SCARECROW gene play crucial and distinct roles in regulating SCARECROW expression in roots and leaves. Plant Mol. Biol., 2017. 94(1-2): p. 1-13 [PMID:28324206] Díaz-Triviño S,Long Y,Scheres B,Blilou I Analysis of a Plant Transcriptional Regulatory Network Using Transient Expression Systems. Methods Mol. Biol., 2017. 1629: p. 83-103 [PMID:28623581] Long Y, et al. In vivo FRET-FLIM reveals cell-type-specific protein interactions in Arabidopsis roots. Nature, 2017. 548(7665): p. 97-102 [PMID:28746306] Yu Q, et al. Cell-Fate Specification in Arabidopsis Roots Requires Coordinative Action of Lineage Instruction and Positional Reprogramming. Plant Physiol., 2017. 175(2): p. 816-827 [PMID:28821591] Spiegelman Z,Lee CM,Gallagher KL KinG Is a Plant-Specific Kinesin That Regulates Both Intra- and Intercellular Movement of SHORT-ROOT. Plant Physiol., 2018. 176(1): p. 392-405 [PMID:29122988] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938]