PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

NNU_021629-RA

Organism

Nelumbo nucifera

Taxonomic ID

4432

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo

Family

WOX

Protein Properties

Length: 362aa MW: 39853.8 Da PI: 7.663

Description

WOX family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
NNU_021629-RA	genome	CAS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	56.4	5.1e-18	53	113	2	57
T--SS--HHHHHHHHHHHHH.SSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 2 rkRttftkeqleeLeelFek.nrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 ++R+++++eq+++Le+ F++ +p ++e++++ ++l ++ +++V++WFqNr+ + k+ NNU_021629-RA 53 KPRWNPKPEQIRILEAIFNSgMVNPPRDEIKRIRAQLqeygQVGDANVFYWFQNRKSRSKH 113 89***************99***********************************995 PP
2	Wus_type_Homeobox	113.6	9.8e-37	52	115	2	65
Wus_type_Homeobox 2 artRWtPtpeQikiLeelyksGlrtPnkeeiqritaeLeeyGkiedkNVfyWFQNrkaRerqkq 65 +++RW+P+peQi+iLe++++sG+++P+++ei+ri+a+L+eyG+++d+NVfyWFQNrk+R+++kq NNU_021629-RA 52 PKPRWNPKPEQIRILEAIFNSGMVNPPRDEIKRIRAQLQEYGQVGDANVFYWFQNRKSRSKHKQ 115 689***********************************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	1.11E-12	48	118	IPR009057	Homeodomain-like
PROSITE profile	PS50071	10.495	49	114	IPR001356	Homeobox domain
SMART	SM00389	2.0E-9	51	118	IPR001356	Homeobox domain
CDD	cd00086	1.33E-8	52	115	No hit	No description
Gene3D	G3DSA:1.10.10.60	3.5E-7	52	119	IPR009057	Homeodomain-like
Pfam	PF00046	1.1E-15	53	113	IPR001356	Homeobox domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008284	Biological Process	positive regulation of cell proliferation
GO:0009735	Biological Process	response to cytokinin
GO:0009793	Biological Process	embryo development ending in seed dormancy
GO:0010075	Biological Process	regulation of meristem growth
GO:0005634	Cellular Component	nucleus
GO:0005737	Cellular Component	cytoplasm
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 362 aa Download sequence Send to blast
MASSNRHWPS MFKSKPSHHQ WQHDINPSLM SSPCQKAPYA SVTGCEERSP EPKPRWNPKP 60 EQIRILEAIF NSGMVNPPRD EIKRIRAQLQ EYGQVGDANV FYWFQNRKSR SKHKQRHLQS 120 AKAQTLQTIP ITTAPATTAV LPSSSSSSSE KSPPRRTDKT PPMGGTNMIE ASNSPTASVN 180 QTYFHPQVDF QPEPFLFPVQ PPPSFSQEFC FSELSNVVQA SDSDHQLTWP CSGGLLLNDI 240 INQGASKKDD QVKMKPTQQF NYSTISTAPV TSAIASTTTA TLNQIQGVDE SGGMIPAAVA 300 KSTVFINDVA FEVAMGPLNV REAFGEDAVL VHSSGLPVIT DEWGVTLQAL QHGAFYYLVR 360 AV

Sequence ? help Back to Top

Protein Sequence Length: 362 aa Download sequence Send to blast

MASSNRHWPS MFKSKPSHHQ WQHDINPSLM SSPCQKAPYA SVTGCEERSP EPKPRWNPKP  60
EQIRILEAIF NSGMVNPPRD EIKRIRAQLQ EYGQVGDANV FYWFQNRKSR SKHKQRHLQS  120
AKAQTLQTIP ITTAPATTAV LPSSSSSSSE KSPPRRTDKT PPMGGTNMIE ASNSPTASVN  180
QTYFHPQVDF QPEPFLFPVQ PPPSFSQEFC FSELSNVVQA SDSDHQLTWP CSGGLLLNDI  240
INQGASKKDD QVKMKPTQQF NYSTISTAPV TSAIASTTTA TLNQIQGVDE SGGMIPAAVA  300
KSTVFINDVA FEVAMGPLNV REAFGEDAVL VHSSGLPVIT DEWGVTLQAL QHGAFYYLVR  360
AV

Functional Description ? help Back to Top
Source	Description
UniProt	Homeodomain transcription factor required for meristem growth and early development (PubMed:15753038). Promotes cell proliferation and prevents premature differentiation in meristematic tissues during postembryonic development (PubMed:15753038). Essential for maintaining tissue growth during embryogenesis (PubMed:17706632). May act by repressing TSS to promote meristematic proliferation (PubMed:21185286). Involved in the transcriptional activation of a subset of cytokinin response factors (PubMed:20110319). May act as a negative regulator of cytokinin signaling in the dark (PubMed:21057190). {ECO:0000269\|PubMed:15753038, ECO:0000269\|PubMed:17706632, ECO:0000269\|PubMed:20110319, ECO:0000269\|PubMed:21057190, ECO:0000303\|PubMed:21185286}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated in the zygote after fertilization by the transcription factor WRKY2. {ECO:0000269\|PubMed:21316593}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010279211.1	0.0	PREDICTED: WUSCHEL-related homeobox 9-like
Swissprot	Q6X7J4	6e-88	WOX9_ARATH; WUSCHEL-related homeobox 9
TrEMBL	A0A1U8BPQ7	0.0	A0A1U8BPQ7_NELNU; WUSCHEL-related homeobox 9-like
STRING	XP_010279211.1	0.0	(Nelumbo nucifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G33880.1	7e-64	homeobox-3

Publications ? help Back to Top
Wang W, et al. Dwarf Tiller1, a Wuschel-related homeobox transcription factor, is required for tiller growth in rice. PLoS Genet., 2014. 10(3): p. e1004154 [PMID:24625559] Zhu T,Moschou PN,Alvarez JM,Sohlberg JJ,von Arnold S Wuschel-related homeobox 8/9 is important for proper embryo patterning in the gymnosperm Norway spruce. J. Exp. Bot., 2014. 65(22): p. 6543-52 [PMID:25205582] Raines T, et al. The cytokinin response factors modulate root and shoot growth and promote leaf senescence in Arabidopsis. Plant J., 2016. 85(1): p. 134-47 [PMID:26662515] Dolzblasz A, et al. Stem Cell Regulation by Arabidopsis WOX Genes. Mol Plant, 2016. 9(7): p. 1028-39 [PMID:27109605] Blein T,Pautot V,Laufs P Combinations of Mutations Sufficient to Alter Arabidopsis Leaf Dissection. Plants (Basel), 2013. 2(2): p. 230-47 [PMID:27137374]