PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

NNU_022872-RA

Organism

Nelumbo nucifera

Taxonomic ID

4432

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo

Family

WRKY

Protein Properties

Length: 622aa MW: 67001.6 Da PI: 6.0544

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
NNU_022872-RA	genome	CAS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.8	2.9e-30	260	319	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a Cpv+k+v+r+aed +++++tYeg+Hnh+ NNU_022872-RA 260 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApACPVRKQVQRCAEDMSILITTYEGTHNHP 319 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	9.5E-32	245	321	IPR003657	WRKY domain
SuperFamily	SSF118290	4.05E-27	253	321	IPR003657	WRKY domain
PROSITE profile	PS50811	28.461	255	321	IPR003657	WRKY domain
SMART	SM00774	2.2E-36	260	320	IPR003657	WRKY domain
Pfam	PF03106	9.6E-27	261	319	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 622 aa Download sequence Send to blast
MDATIRSCLG GPIKDEKRAD QSCGDDDGSR ELEKLCDGRQ VHDDNGSKPS SPNQKETTIS 60 KQVSTETSPM QNILRAPSSI KKDQEEKLES AKAEMGEVRE ENERLKMVLA RIVKDYQSLQ 120 TKFFGIAQQE AATQFADTAP KDQEIEEPEL VSLSLGRIST EPKKEEKNSN SSKCKEDDHE 180 GLSLGLDCKF EVSNPGSTER ASNPSPENSL EEPKEEEAGE TWPPSKFLKT MRSGDDEVSQ 240 QTQVKKARVS VRARCDTPTM NDGCQWRKYG QKIAKGNPCP RAYYRCTVAP ACPVRKQVQR 300 CAEDMSILIT TYEGTHNHPL PVSATAMAST TSAAASMLMS GSISSRPTLA GASLGPLATN 360 TTSAADLHGL NFNLADNTRA RPSFYLPSSS VSSSTTYPTI TLDLTAPPSS SASSSSFQLN 420 RLSTSNFPAQ RYSPTSFNFS STESNSQPTW GNGYLSYGTQ PYNKNQQQLG SLSLGRQPQE 480 SFYQAYMQKN NPAAPSQQSL TESIAAATKA ITSDPSFRSA LAAAIASIVG SGNSGTTTQG 540 NQGSGENFGQ NLKWGEQFSA VPPYTSTTPN GNGCASSFLN RSASSNTQQG SLMFLPPALP 600 FSTSKSASAS PVDNRDHINI NX

Sequence ? help Back to Top

Protein Sequence Length: 622 aa Download sequence Send to blast

MDATIRSCLG GPIKDEKRAD QSCGDDDGSR ELEKLCDGRQ VHDDNGSKPS SPNQKETTIS  60
KQVSTETSPM QNILRAPSSI KKDQEEKLES AKAEMGEVRE ENERLKMVLA RIVKDYQSLQ  120
TKFFGIAQQE AATQFADTAP KDQEIEEPEL VSLSLGRIST EPKKEEKNSN SSKCKEDDHE  180
GLSLGLDCKF EVSNPGSTER ASNPSPENSL EEPKEEEAGE TWPPSKFLKT MRSGDDEVSQ  240
QTQVKKARVS VRARCDTPTM NDGCQWRKYG QKIAKGNPCP RAYYRCTVAP ACPVRKQVQR  300
CAEDMSILIT TYEGTHNHPL PVSATAMAST TSAAASMLMS GSISSRPTLA GASLGPLATN  360
TTSAADLHGL NFNLADNTRA RPSFYLPSSS VSSSTTYPTI TLDLTAPPSS SASSSSFQLN  420
RLSTSNFPAQ RYSPTSFNFS STESNSQPTW GNGYLSYGTQ PYNKNQQQLG SLSLGRQPQE  480
SFYQAYMQKN NPAAPSQQSL TESIAAATKA ITSDPSFRSA LAAAIASIVG SGNSGTTTQG  540
NQGSGENFGQ NLKWGEQFSA VPPYTSTTPN GNGCASSFLN RSASSNTQQG SLMFLPPALP  600
FSTSKSASAS PVDNRDHINI NX

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	1e-20	247	321	1	74	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010242382.1	0.0	PREDICTED: probable WRKY transcription factor 72
Swissprot	A0A3Q7GFB5	1e-133	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A1U7Z4T2	0.0	A0A1U7Z4T2_NELNU; probable WRKY transcription factor 72
STRING	XP_010242382.1	0.0	(Nelumbo nucifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	1e-80	WRKY DNA-binding protein 72

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]