PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID NNU_022880-RA
Organism
Nelumbo nucifera
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo
Family bHLH
Protein Properties Length: 619aa    MW: 68008.9 Da    PI: 5.9934
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
NNU_022880-RAgenomeCASView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH39.21.2e-12463509455
                    HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
            HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                    +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  NNU_022880-RA 463 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAITYITELQ 509
                    799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142152.8E-5454242IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.876459508IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000835.11E-15462513No hitNo description
SuperFamilySSF474592.22E-18462524IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000104.2E-10463509IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.8E-18463525IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.0E-16465514IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 619 aa     Download sequence    Send to blast
MGVETGLGLG GGFWNDEDKA TIVAVLGSRA FDYLTTSTVS SEGLMTAVGN DADLQNKLSE  60
LVDGPNASNF TWNYAIFWQI SSSKTGELVL GWGDGYCREP KEGEESEVTH DLSLRVDDET  120
QQKMRKRVLQ KLQTVFGGPD EESYAFGLDR VTDTEMFFLA SMYFFFPQGE GAPGKAFGSG  180
KHLWISDALK SPFDYCVRSF LARAAGIQTI VLVPTDTGVA ELGSVRSIPE NLEVLQTIKF  240
MFSTSASLPF QVKPLAAAPV LNEKKDNGVI ASGFGSGART DEFPKIFGQD LNPSRSQLSE  300
KPIVAKVEER PWEAYANGNG LPFQNSRKGL HAVGSSWFHG VKQGATAEVI SSQNTGNNQQ  360
KLGNTALMIS NDVDPAHRSL GHCNGVREDS RLCQFQAQKQ APRQIDFSGA TSRTSVIARQ  420
STIESEHSDV EASCKEDRLG PVDEKRPRKR GRKPANGREE PLNHVEAERQ RREKLNQRFY  480
ALRAVVPNIS KMDKASLLGD AITYITELQK KLKDLESEKE KFGNQSRDTV ASEANSSGQN  540
SKRGLDIDIQ SXHDEVIVRA SCPLDIHPVS RVINAFKEAE ITVVESKISA GNDTVFHTFV  600
VNSQGSEQLT KDKLVLHFN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A5e-30457525270Transcription factor MYC2
5gnj_B5e-30457525270Transcription factor MYC2
5gnj_E5e-30457525270Transcription factor MYC2
5gnj_F5e-30457525270Transcription factor MYC2
5gnj_G5e-30457525270Transcription factor MYC2
5gnj_I5e-30457525270Transcription factor MYC2
5gnj_M5e-30457525270Transcription factor MYC2
5gnj_N5e-30457525270Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1444452KRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010242396.10.0PREDICTED: transcription factor bHLH13-like
RefseqXP_010242398.10.0PREDICTED: transcription factor bHLH13-like
RefseqXP_010242399.10.0PREDICTED: transcription factor bHLH13-like
RefseqXP_019051449.10.0PREDICTED: transcription factor bHLH13-like
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A1U7YTE80.0A0A1U7YTE8_NELNU; transcription factor bHLH13-like
STRINGXP_010242395.10.0(Nelumbo nucifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.31e-168bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]