PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID NNU_025234-RA
Organism
Nelumbo nucifera
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo
Family C2H2
Protein Properties Length: 405aa    MW: 45645.8 Da    PI: 6.1254
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
NNU_025234-RAgenomeCASView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.20.00056100122323
                    ET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                    C+   Cgk+F +   L++H   H
  NNU_025234-RA 100 CSyeGCGKTFIDAGALRKHSHIH 122
                    77779**************7766 PP
2zf-C2H222.14.1e-07171195123
                    EEET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                    ++Cp   Cgk Fs   nL+ H+rtH
  NNU_025234-RA 171 FVCPheGCGKAFSLDFNLRAHMRTH 195
                    89**********************9 PP
3zf-C2H217.41.3e-05201225123
                    EEET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                    + Cp  dCgk++ + + Lk+Hi+ H
  NNU_025234-RA 201 HICPyvDCGKRYAHEYKLKTHIKAH 225
                    68*********************96 PP
4zf-C2H213.30.00025264289123
                    EEET..TTTEEESSHHHHHHHHHH.T CS
        zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                    y Cp   C+k++ + + L+ H+++ H
  NNU_025234-RA 264 YACPyeGCDKCYIHEYKLNLHLKReH 289
                    89*********************999 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.602.7E-1394124IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576674.77E-695134No hitNo description
PROSITE profilePS5015710.78398127IPR007087Zinc finger, C2H2
SMARTSM003550.003298122IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280100122IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.6E-9125163IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM0035558127165IPR015880Zinc finger, C2H2-like
SuperFamilySSF576673.13E-15152205No hitNo description
Gene3DG3DSA:3.30.160.601.1E-19164194IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.944171200IPR007087Zinc finger, C2H2
SMARTSM003552.9E-4171195IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280173195IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.8E-10195227IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.951201230IPR007087Zinc finger, C2H2
SMARTSM003550.0075201225IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280203226IPR007087Zinc finger, C2H2
SuperFamilySSF576672.87E-5259287No hitNo description
Gene3DG3DSA:3.30.160.609.2E-8260286IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.224264294IPR007087Zinc finger, C2H2
SMARTSM003550.014264289IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280266289IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 405 aa     Download sequence    Send to blast
MRFLGGEEFA RKIFGELEER GCVPSRGREG NTVVGEEVCL HARNADDQDR MRCSGVVEIG  60
NVGDSGLKAE DTLKALKEKA KEPEPEEPEP EPSTEVLFLC SYEGCGKTFI DAGALRKHSH  120
IHGERQYVCH YEGCGKALSA ILIAQCFILQ KFLDSSKLKR HFLIHTGERH FVCPHEGCGK  180
AFSLDFNLRA HMRTHSQENY HICPYVDCGK RYAHEYKLKT HIKAHHEKNM AMDAMKHTPP  240
SEKLPNTSKP SAVGYGSASS DRPYACPYEG CDKCYIHEYK LNLHLKREHP GHNLEENGKH  300
AATDADNEMD EASDQDAYAG KSGSGKNSKR SKPKPVSKMP PAKIAQRKGS SAPPANLNVI  360
KKQWPSKDMY EEEDSEETEE DRDNVEDGWR YAENNEDDEE TEYED
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C1e-31912252119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010246046.10.0PREDICTED: uncharacterized zinc finger protein At4g06634
SwissprotQ2V3L31e-118YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A1U7Z1V60.0A0A1U7Z1V6_NELNU; uncharacterized zinc finger protein At4g06634
STRINGXP_010246046.10.0(Nelumbo nucifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.21e-113C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]