PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_10606_f_1

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

ERF

Protein Properties

Length: 252aa MW: 28212.4 Da PI: 6.8107

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_10606_f_1	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	59.7	7e-19	122	172	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y+G+r+++ +g+++AeIrd ++ng +r++lg+++t+e+Aa a+++a+ k++g Neem_10606_f_1 122 HYRGIRRRP-SGKFAAEIRDRKKNG--ARVWLGTYDTPEGAAMAYDRAAYKMRG 172 6******.7*****77787..***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF00847	1.6E-13	122	172	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	22.115	122	180	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	7.85E-21	122	181	IPR016177	DNA-binding domain
CDD	cd00018	9.78E-29	122	180	No hit	No description
Gene3D	G3DSA:3.30.730.10	2.4E-29	122	180	IPR001471	AP2/ERF domain
SMART	SM00380	1.3E-34	122	186	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.6E-11	123	134	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.6E-11	162	182	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 252 aa Download sequence Send to blast
MYTTESIIPE SELALLESIR QFLLDDDLDV PITFPSETIN APLYSPQYST SSSAGSVFVT 60 ENLSNSNSVT YVETDAYRAL PDAINEGWIS FDQLDHEIDH KMETHTPTTN QLEAREADVR 120 VHYRGIRRRP SGKFAAEIRD RKKNGARVWL GTYDTPEGAA MAYDRAAYKM RGSKAKLNFP 180 LLIGSTNFVK AVRPTNKHRS PEASSSSSSS FALHGGSPKS QTEKYWNITS VFPNLADRKV 240 ELIFPRQDSV GR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	2e-27	122	185	5	68	ATERF1
3gcc_A	2e-27	122	185	5	68	ATERF1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as a transcriptional activator and may be involved in disease resistance pathways. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways mediated by ethylene, that seems to depend on a protein kinase cascade, and to be influenced by methyl-jasmonate. {ECO:0000269\|PubMed:10652129, ECO:0000269\|PubMed:10792818, ECO:0000269\|PubMed:7756828, ECO:0000269\|Ref.2}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by ethephon (ethylene-releasing compound) in buds and to a lower extent in leaves. Strongly induced by cycloheximide and mechanical stimuli. Wounding leads to a both local and systemic expression, independently of ethylene, and through a de-novo-protein-synthesis-independent regulation. Wound induction is reduced by methyl-jasmonate. Induction by purified xylanase from Trichoderma viride (TvX) and another elicitor from Phytophthora infestans (PiE), that appears to be mediated by both protein kinases and protein phosphatases. {ECO:0000269\|PubMed:10652129, ECO:0000269\|PubMed:12090623, ECO:0000269\|PubMed:7756828, ECO:0000269\|Ref.2}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006445417.1	1e-53	pathogenesis-related genes transcriptional activator PTI5
Refseq	XP_015381357.1	1e-53	pathogenesis-related genes transcriptional activator PTI5-like
Swissprot	Q40479	2e-37	ERF2_TOBAC; Ethylene-responsive transcription factor 2
TrEMBL	V4TYJ2	3e-52	V4TYJ2_9ROSI; Uncharacterized protein
STRING	XP_006445417.1	6e-53	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G44840.1	3e-37	ethylene-responsive element binding factor 13

Publications ? help Back to Top
Nakano T,Nishiuchi T,Suzuki K,Fujimura T,Shinshi H Studies on transcriptional regulation of endogenous genes by ERF2 transcription factor in tobacco cells. Plant Cell Physiol., 2006. 47(4): p. 554-8 [PMID:16452120]