PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_1088_f_4
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family E2F/DP
Protein Properties Length: 399aa    MW: 43700.8 Da    PI: 6.9553
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_1088_f_4genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP581.5e-181722283071
        E2F_TDP  30 vakeLvse................dvknkrRRiYDilNVLealnliekkekneirwkg 71 
                    va+eLv+e                d+kn+rRR+YD+lNVL+a+++i+k +k+ei+wkg
  Neem_1088_f_4 172 VADELVAEfadpsnslaspdqqqyDEKNIRRRVYDALNVLMAMDIISK-DKKEIQWKG 228
                    899**999****************************************.*******98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.108.0E-1899142IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.5E-30100228IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.5E-20102228IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467859.98E-17103128IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.3E-28171233IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467859.98E-17174229IPR011991Winged helix-turn-helix DNA-binding domain
CDDcd144583.48E-45233336IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440741.31E-43234348No hitNo description
SMARTSM011386.8E-78235397IPR014889Transcription factor DP, C-terminal
PfamPF087811.1E-41236343IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 399 aa     Download sequence    Send to blast
MVTGNNSHHQ EDGERNPPAT AASRGGGGGA TRSWGTTISG QSVSTSGSVG SPSQGMATPA  60
SDNTFLRLNH LDIHGDDAGS QAAVGSKKKK RGQRAVGGDK SGRGLRQFSM KVCEKVESKG  120
RTTYNEVRDT TCGFNDKNLV VQVTKSPHPH LSFWGLSLCP FLCHSSENGY MVADELVAEF  180
ADPSNSLASP DQQQYDEKNI RRRVYDALNV LMAMDIISKD KKEIQWKGLP RTSLNDIEEL  240
KAERLGLRNR IEKKAAYLQE LEEQYVGLQN LIQRNEQLYS SGNAPSGGVA LPFILVQTRP  300
HATVEVEISE DMQLVHFDFN STPFELHDDN YVLKAMKFCE RPESDGMVQS FPADGGEGSS  360
MAGLYQPQQL PPPRSNNPSR PPTSPPVPGI LKARVKHEH
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B4e-2994233193PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017977428.10.0PREDICTED: transcription factor-like protein DPB
SwissprotQ9FNY21e-154DPB_ARATH; Transcription factor-like protein DPB
TrEMBLA0A067E7Y30.0A0A067E7Y3_CITSI; Uncharacterized protein
TrEMBLV4SRN50.0V4SRN5_9ROSI; Uncharacterized protein
STRINGXP_006491709.10.0(Citrus sinensis)
STRINGXP_006428365.10.0(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM61392641
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03415.11e-144Transcription factor DP