PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_19819_f_1

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

WRKY

Protein Properties

Length: 166aa MW: 18903.4 Da PI: 10.494

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_19819_f_1	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	109.5	1.6e-34	15	73	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 ldDgy+WrKYGqK+vkg+++prsYY+Ct++gC+v+k+ver+++dpk+v++tYeg+Hnh+ Neem_19819_f_1 15 LDDGYRWRKYGQKVVKGNPYPRSYYKCTTPGCNVRKHVERASTDPKAVVTTYEGKHNHD 73 59********************************************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.5E-37	2	75	IPR003657	WRKY domain
SuperFamily	SSF118290	1.57E-30	7	75	IPR003657	WRKY domain
PROSITE profile	PS50811	38.744	10	75	IPR003657	WRKY domain
SMART	SM00774	2.4E-39	15	74	IPR003657	WRKY domain
Pfam	PF03106	1.0E-26	16	73	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 166 aa Download sequence Send to blast
EPRIIVQTTS EVDLLDDGYR WRKYGQKVVK GNPYPRSYYK CTTPGCNVRK HVERASTDPK 60 AVVTTYEGKH NHDVPAAKSS SHNTANNNAS QIQPQNARTD FGNNNQQPVA RLRHDKRPQD 120 KQKRRSAVIR HVFKNLFLTL MAIVFIMLLE KAFPETSMDI AIAKNG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	1e-47	6	76	8	78	Probable WRKY transcription factor 4
2lex_A	1e-47	6	76	8	78	Probable WRKY transcription factor 4
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	119	124	DKQKRR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid and during leaf senescence. {ECO:0000269\|PubMed:11449049, ECO:0000269\|PubMed:11722756}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021299606.1	4e-66	probable WRKY transcription factor 3
Swissprot	Q9ZQ70	1e-55	WRKY3_ARATH; Probable WRKY transcription factor 3
TrEMBL	G3FFB0	2e-72	G3FFB0_9ROSI; WRKY transcription factor 2-4
STRING	EOY01812	3e-64	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1534	27	92

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G03340.1	4e-52	WRKY DNA-binding protein 3

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Aamir M, et al. Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach. Front Plant Sci, 2017. 8: p. 819 [PMID:28611792]