PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_2935_f_3

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

C2H2

Protein Properties

Length: 454aa MW: 50634.5 Da PI: 5.1603

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_2935_f_3	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	15.1	6.5e-05	96	118	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++Cp+Cg+ F++ ++ H ++ Neem_2935_f_3 96 FECPICGQAFKTEDEVSIHVESC 118 89***************998776 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50157	8.787	96	125	IPR007087	Zinc finger, C2H2
CDD	cd09212	6.27E-21	146	241	No hit	No description
SuperFamily	SSF143503	1.12E-17	157	239	IPR018997	PUB domain
SMART	SM00580	9.0E-17	159	226	IPR018997	PUB domain
Pfam	PF09409	1.6E-16	159	217	IPR018997	PUB domain
SuperFamily	SSF54236	2.0E-7	306	429	IPR029071	Ubiquitin-related domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0050832	Biological Process	defense response to fungus
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 454 aa Download sequence Send to blast
MDDMKDKMKA PANPNLARQN IYQTTNSKPK PKANPTSSLN QNSSSLPRKP LGSEQSQSSS 60 VNKPETNREP ANGFDPYESL ITSGKRSQTG YSLNVFECPI CGQAFKTEDE VSIHVESCVN 120 STNNNNLVDN SSGNGTVDDS RSELEACVGT FLSEKPKEGS VEVVLRLLRN VVREPENEKF 180 RRIRMSNPKI REAVGEVAGG VELLEIVGFE LREDGGEMWA TIEVPDKRSI GLISKVIELL 240 EPKKVEEPKK GENLKVEAPA ETEEPVEQKP VDRQIRVFFA VPESVASRIE LPDSFYNLSI 300 GELKREAEMR KKRIDESQLL IPKSYREKQA KAARKRYTKA VICIQFPDGV LLQGIFGPWE 360 QTTALYERKD TVASLGMFVS SALKEPTLQY DLINPASIKR RLVPRFPAPG QKATTLEEED 420 LVPSALIKFR PIETDSAVFT GLSNELLQII EPLE

Sequence ? help Back to Top

Protein Sequence Length: 454 aa Download sequence Send to blast

MDDMKDKMKA PANPNLARQN IYQTTNSKPK PKANPTSSLN QNSSSLPRKP LGSEQSQSSS  60
VNKPETNREP ANGFDPYESL ITSGKRSQTG YSLNVFECPI CGQAFKTEDE VSIHVESCVN  120
STNNNNLVDN SSGNGTVDDS RSELEACVGT FLSEKPKEGS VEVVLRLLRN VVREPENEKF  180
RRIRMSNPKI REAVGEVAGG VELLEIVGFE LREDGGEMWA TIEVPDKRSI GLISKVIELL  240
EPKKVEEPKK GENLKVEAPA ETEEPVEQKP VDRQIRVFFA VPESVASRIE LPDSFYNLSI  300
GELKREAEMR KKRIDESQLL IPKSYREKQA KAARKRYTKA VICIQFPDGV LLQGIFGPWE  360
QTTALYERKD TVASLGMFVS SALKEPTLQY DLINPASIKR RLVPRFPAPG QKATTLEEED  420
LVPSALIKFR PIETDSAVFT GLSNELLQII EPLE

Functional Description ? help Back to Top
Source	Description
UniProt	Facilitates the interaction of SYP31 and CDC48A, thereby regulating an CDC48A membrane-associated function (Ref.8). Appears to act as a negative regulator mediating the powdery mildew-plant interaction (PubMed:19176722, PubMed:23301616). {ECO:0000269\|PubMed:19176722, ECO:0000269\|PubMed:23301616, ECO:0000269\|Ref.8}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in response to powdery mildew and by benzothiadiazole (BTH) treatment. {ECO:0000269\|PubMed:19176722}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006469232.1	0.0	plant UBX domain-containing protein 2
Swissprot	Q9ZU93	1e-167	PUX2_ARATH; Plant UBX domain-containing protein 2
TrEMBL	A0A067FB39	0.0	A0A067FB39_CITSI; Uncharacterized protein
STRING	XP_006469232.1	0.0	(Citrus sinensis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM9835	16	18

Publications ? help Back to Top
Suzuki T,Park H,Till EA,Lennarz WJ The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway. Biochem. Biophys. Res. Commun., 2001. 287(5): p. 1083-7 [PMID:11587532] Rancour DM,Park S,Knight SD,Bednarek SY Plant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48. J. Biol. Chem., 2004. 279(52): p. 54264-74 [PMID:15498773] Chandran D,Rickert J,Cherk C,Dotson BR,Wildermuth MC Host cell ploidy underlying the fungal feeding site is a determinant of powdery mildew growth and reproduction. Mol. Plant Microbe Interact., 2013. 26(5): p. 537-45 [PMID:23301616]