PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_35085_f_1
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family bHLH
Protein Properties Length: 235aa    MW: 26448.9 Da    PI: 8.1015
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_35085_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH41.32.9e-134692455
                    HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
             HLH  4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55
                    +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  Neem_35085_f_1 46 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAITYITDLQ 92
                    799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088816.8314291IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474593.53E-1945111IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.44E-134596No hitNo description
PfamPF000109.5E-114692IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.105.0E-1946112IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003535.4E-144897IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 235 aa     Download sequence    Send to blast
MVVGGFDAQA RLSGLEQKDD SSPQADERKP RKRGRKPANG REEPLNHVEA ERQRREKLNQ  60
RFYALRAVVP NISKMDKASL LGDAITYITD LQMKIRVLET EKEMVNNKQK QIAVPEIDFQ  120
PRHDDAIVRV SCPLDTHPVC SVMKAFSEHQ IVAQDSNVST TEDKVIHTFS VRTQGGGAEQ  180
LKEKLFSLRG AHSSCYAHAP TVGKDEDAAV YFFIVQALAR KGETEEIFDK QRGFV
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A3e-3140114276Transcription factor MYC2
5gnj_B3e-3140114276Transcription factor MYC2
5gnj_E3e-3140114276Transcription factor MYC2
5gnj_F3e-3140114276Transcription factor MYC2
5gnj_G3e-3140114276Transcription factor MYC2
5gnj_I3e-3140114276Transcription factor MYC2
5gnj_M3e-3140114276Transcription factor MYC2
5gnj_N3e-3140114276Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
12735RKPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006479569.11e-118transcription factor bHLH3
RefseqXP_024044801.11e-118transcription factor bHLH3
SwissprotA0A3Q7H2169e-81MTB3_SOLLC; Transcription factor MTB3
TrEMBLA0A2H5QGS31e-117A0A2H5QGS3_CITUN; Uncharacterized protein
STRINGXP_006479569.11e-118(Citrus sinensis)
STRINGXP_006443887.11e-118(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM66112741
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16430.13e-79bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]