PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_6269_f_2

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

bHLH

Protein Properties

Length: 315aa MW: 35277.8 Da PI: 4.8154

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_6269_f_2	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	36.9	6.6e-12	149	192	6	54
HHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS HLH 6 nerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 ++ErrRR+r+N++++ Lr+++Pk + K++ +iL +++Y+k+L Neem_6269_f_2 149 LMAERRRRKRLNDRLSMLRSIVPKiS------KMDRTSILGDTIDYMKEL 192 589*******************66......**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.491	143	192	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.57E-15	146	207	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.3E-12	149	198	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.2E-9	149	192	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	4.81E-5	150	196	No hit	No description
Gene3D	G3DSA:4.10.280.10	2.9E-15	150	206	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd04873	0.00374	241	282	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 315 aa Download sequence Send to blast
MQINNFPSGW NFDSLDENPS LVAASSNPSF LGFTAPPEPS FECPFSDQAY TFVDGLAIPE 60 IDTSSYACRN DTALYPSQAQ AQDYPSIVEE DGLGLLRTDC HHCFEERNTS CTVENMEQLK 120 NNIQVFNMGL CGEKKNKNKK LEGQPSKNLM AERRRRKRLN DRLSMLRSIV PKISKMDRTS 180 ILGDTIDYMK ELLERINKLQ EEETQVGSNQ LLTGNLTELK SNEVLVRNSP KFDVQRRETD 240 TRIDICCAAK PGLLLSTVST LEALGLGIQQ CVISCFNDFS MQASCSEAPE QRTLLSSEDI 300 KQALFRNAGY GGRCL

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	151	158	ERRRRKRL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. May be involved in the differentiation of stomatal guard cells. {ECO:0000269\|PubMed:17088607}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KP689416	4e-41	KP689416.1 Prunus pseudocerasus isolate Unigene13488 bHLH transcription factor mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_022740912.1	1e-154	transcription factor bHLH93-like
Swissprot	Q9LSL1	4e-91	BH093_ARATH; Transcription factor bHLH93
TrEMBL	A0A061DIW8	1e-150	A0A061DIW8_THECC; DNA binding protein, putative isoform 1
STRING	EOX91851	1e-151	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2043	28	78

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G65640.1	7e-90	beta HLH protein 93

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Sharma N, et al. NO FLOWERING IN SHORT DAY (NFL) is a bHLH transcription factor that promotes flowering specifically under short-day conditions in Arabidopsis. Development, 2016. 143(4): p. 682-90 [PMID:26758694] Chen YS, et al. Two MYB-related transcription factors play opposite roles in sugar signaling in Arabidopsis. Plant Mol. Biol., 2017. 93(3): p. 299-311 [PMID:27866313] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]