PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_6825_f_1
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family ERF
Protein Properties Length: 243aa    MW: 27096.3 Da    PI: 6.3155
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_6825_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP258.81.3e-1895144355
            AP2   3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                    y+GVr ++ +g+++AeIrd + ng   r++lg+f++ae Aa a+++a+ +++g
  Neem_6825_f_1  95 YRGVRKRP-WGKYAAEIRDSTRNG--VRVWLGTFDSAEAAALAYDQAAFSMRG 144
                    9*******.**********44465..*************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM003802.3E-3794158IPR001471AP2/ERF domain
PfamPF008474.2E-1394144IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.105.7E-3094152IPR001471AP2/ERF domain
PROSITE profilePS5103222.69594152IPR001471AP2/ERF domain
SuperFamilySSF541713.47E-2295154IPR016177DNA-binding domain
PRINTSPR003673.3E-1095106IPR001471AP2/ERF domain
CDDcd000183.98E-2095153No hitNo description
PRINTSPR003673.3E-10118134IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0006952Biological Processdefense response
GO:0009873Biological Processethylene-activated signaling pathway
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 243 aa     Download sequence    Send to blast
MESSFLSYPK PEFSPASSFG SSHDSLSWDE LLLSHNSLPF NINDSEEMLL LGVLAEGTTK  60
LESSESISVD GVNKEEEVTS SSKTVEESSK KERSYRGVRK RPWGKYAAEI RDSTRNGVRV  120
WLGTFDSAEA AALAYDQAAF SMRGSLATLN FPIEMVKESL QEMKYRCEDG CSPVVALKRR  180
HSMRKKSSTV NKKSKKKELI DHHHHHQVQV GSQNVVVLED LGADYLEQLL MSSCESSGAT  240
PNW
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A2e-2893155163ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269|PubMed:23057995, ECO:0000269|PubMed:28733419}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00374DAPTransfer from AT3G23240Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269|PubMed:28733419}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023906372.16e-92ethylene-responsive transcription factor 1B-like
SwissprotA0A3Q7I5Y92e-74ERFC3_SOLLC; Ethylene-response factor C3
TrEMBLD8VD371e-99D8VD37_ACTDE; Ethylene response factor 10
STRINGEOX944712e-85(Theobroma cacao)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM22752876
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G23240.16e-50ethylene response factor 1
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Pirrello J, et al.
    Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene.
    BMC Plant Biol., 2012. 12: p. 190
    [PMID:23057995]
  3. Du M, et al.
    MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato.
    Plant Cell, 2017. 29(8): p. 1883-1906
    [PMID:28733419]