PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_7090_f_3

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

bZIP

Protein Properties

Length: 262aa MW: 28711.1 Da PI: 6.2333

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_7090_f_3	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	27.8	5.4e-09	86	134	3	51
XXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 3 elkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkelee 51 e k+ +r N+eA r++R++Kka+ + Le++v L a N++L k+l+ Neem_7090_f_3 86 ETKAKKRPLGNKEAVRKYREKKKARAASLEDEVVRLRAVNQQLMKRLQG 134 6799999*************************************99974 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.20.5.170	1.1E-13	82	152	No hit	No description
SMART	SM00338	1.9E-10	84	151	IPR004827	Basic-leucine zipper domain
Pfam	PF07716	1.9E-12	85	141	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	8.818	86	133	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	5.69E-7	88	134	No hit	No description
CDD	cd14686	5.97E-11	89	143	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0071294	Biological Process	cellular response to zinc ion
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 262 aa Download sequence Send to blast
MDDGEVDFSN QEVFPSANMG DFPSCSMDSF FEEILKDTHA CTHTHTCNPP GPDSSHTHTC 60 FHVHTKIVAA QSEDKVSTDD TAESTETKAK KRPLGNKEAV RKYREKKKAR AASLEDEVVR 120 LRAVNQQLMK RLQGQAALEA EIARLKCLLV DIRGRIEGEI GSFPYQKSVN NLNMPNPHLS 180 SAYVMNPCNM QCNDQVYCLH SGVEGKSGED LALNGQAFNG CEFENLQCLV NQNSGVKELS 240 GCGVGDVATK VNSSANKRKG EA

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the response to zinc ion deficiency. Binds to the consensus sequence 5'-[AG]TGTCGACA[CT]-3' also called zinc deficiency response element (ZDRE). The ZDRE sequence is conserved in the plant kingdom and present in the promoters of genes that constitute the primary response to zinc deficiency, comprising additional ZIP metal transporter genes (PubMed:20479230, PubMed:26306426). Required for zinc accumulation in roots. Mediates the expression of the zinc transporter ZIP12 during growth in zinc-deficient conditions. ZIP12 transporter is involved in zinc uptake in roots (PubMed:26306426). {ECO:0000269\|PubMed:20479230, ECO:0000269\|PubMed:26306426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by zinc deficiency. {ECO:0000269\|PubMed:20479230}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006422598.1	1e-165	basic leucine zipper 23
Refseq	XP_006486739.1	1e-165	basic leucine zipper 23
Refseq	XP_006486740.1	1e-165	basic leucine zipper 23
Refseq	XP_006486741.1	1e-165	basic leucine zipper 23
Refseq	XP_024034524.1	1e-165	basic leucine zipper 23
Refseq	XP_024034525.1	1e-165	basic leucine zipper 23
Refseq	XP_024958012.1	1e-165	basic leucine zipper 23
Swissprot	Q8GTS2	1e-112	BZP23_ARATH; Basic leucine zipper 23
TrEMBL	A0A067FXY2	1e-164	A0A067FXY2_CITSI; Uncharacterized protein
STRING	XP_006486739.1	1e-164	(Citrus sinensis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2036	28	79

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G16770.1	1e-101	bZIP family protein

Publications ? help Back to Top
Azevedo H, et al. Transcriptomic profiling of Arabidopsis gene expression in response to varying micronutrient zinc supply. Genom Data, 2016. 7: p. 256-8 [PMID:26981422] Castro PH, et al. Phylogenetic analysis of F-bZIP transcription factors indicates conservation of the zinc deficiency response across land plants. Sci Rep, 2017. 7(1): p. 3806 [PMID:28630437] Nazri AZ,Griffin JHC,Peaston KA,Alexander-Webber DGA,Williams LE F-group bZIPs in barley-a role in Zn deficiency. Plant Cell Environ., 2017. 40(11): p. 2754-2770 [PMID:28763829] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]