PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_7365_f_2

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

bHLH

Protein Properties

Length: 321aa MW: 35056.2 Da PI: 4.8458

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_7365_f_2	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	50.7	3.2e-16	110	156	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 hn E+rRR+riN+++ L+ l+P++ K +Ka++L +A+eY+k+Lq Neem_7365_f_2 110 VHNLSEKRRRSRINEKLKALQNLIPNS-----NKTDKASMLDEAIEYLKQLQ 156 6***********************7.....5****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	1.44E-20	103	166	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.3E-20	103	166	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	17.898	106	155	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.90E-18	109	160	No hit	No description
Pfam	PF00010	9.0E-14	110	156	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	7.6E-18	112	161	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 321 aa Download sequence Send to blast
MADLYGTTPP TGQEPEEITS FLNQFIHNSS SSSSSCLFAQ PEDRQRFGRS ADPSVLDSSS 60 GGVNFSNFVV GAVDSDTNES EKGCREISEV PSNDTSRPKT SSKRSRAAEV HNLSEKRRRS 120 RINEKLKALQ NLIPNSNKTD KASMLDEAIE YLKQLQLQVQ MLTMRNGLSL HPMWLPGVLP 180 SMQLPQTGMV FEEGNGLLNT NRGSETLSAN EESSVQTGFN LSDQCNISNQ PIPVPSAANV 240 STSETSFGLG PLIQAHYGPF SLASSSKFVM YKMKILLDVE ENCPILCCAD VEGSLALEHV 300 DLDHQLTRAS EGLLASKFVY N

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that plays a role in floral organogenesis. Promotes the growth of carpel margins and of pollen tract tissues derived from them. {ECO:0000269\|PubMed:10225997, ECO:0000269\|Ref.8}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by the A class gene AP2 in the first whorl and by ARF3/ETT in gynoecium. {ECO:0000269\|PubMed:11245574}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024040747.1	1e-162	LOW QUALITY PROTEIN: transcription factor ALC
Swissprot	Q9FUA4	1e-41	SPT_ARATH; Transcription factor SPATULA
TrEMBL	A0A2H5NH93	1e-161	A0A2H5NH93_CITUN; Uncharacterized protein
STRING	XP_006473301.1	1e-161	(Citrus sinensis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4199	27	54

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36930.1	4e-43	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Pabón-Mora N,Wong GK,Ambrose BA Evolution of fruit development genes in flowering plants. Front Plant Sci, 2014. 5: p. 300 [PMID:25018763] Moubayidin L,Ostergaard L Dynamic control of auxin distribution imposes a bilateral-to-radial symmetry switch during gynoecium development. Curr. Biol., 2014. 24(22): p. 2743-8 [PMID:25455035] Pfannebecker KC,Lange M,Rupp O,Becker A Seed Plant-Specific Gene Lineages Involved in Carpel Development. Mol. Biol. Evol., 2017. 34(4): p. 925-942 [PMID:28087776] Zumajo-Cardona C,Ambrose BA,Pabón-Mora N Evolution of the SPATULA/ALCATRAZ gene lineage and expression analyses in the basal eudicot, Bocconia frutescens L. (Papaveraceae). Evodevo, 2017. 8: p. 5 [PMID:28331573] Reyes-Olalde JI, et al. The bHLH transcription factor SPATULA enables cytokinin signaling, and both activate auxin biosynthesis and transport genes at the medial domain of the gynoecium. PLoS Genet., 2017. 13(4): p. e1006726 [PMID:28388635] Wu M, et al. SPATULA regulates floral transition and photomorphogenesis in a PHYTOCHROME B-dependent manner in Arabidopsis. Biochem. Biophys. Res. Commun., 2018. 503(4): p. 2380-2385 [PMID:29966653]