PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_762_f_1
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family TALE
Protein Properties Length: 182aa    MW: 20918.2 Da    PI: 8.2063
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_762_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox29.61.2e-091261592255
                   SSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
      Homeobox  22 nrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                    +yp+++++  LA+++gL++rq+ +WF N+R ++
  Neem_762_f_1 126 WPYPTEADKLALAESTGLDQRQINNWFINQRKRH 159
                   59*****************************885 PP
2ELK383.4e-1379100122
           ELK   1 ELKhqLlrKYsgyLgsLkqEFs 22 
                   ELK+ LlrKY+gy+++Lk+EFs
  Neem_762_f_1  79 ELKDKLLRKYGGYISTLKHEFS 100
                   9********************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF037895.8E-1179100IPR005539ELK domain
PROSITE profilePS5121310.7727999IPR005539ELK domain
SMARTSM011881.2E-779100IPR005539ELK domain
PROSITE profilePS5007112.79599162IPR001356Homeobox domain
SuperFamilySSF466892.1E-20100176IPR009057Homeodomain-like
SMARTSM003896.8E-13101166IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.606.2E-28104163IPR009057Homeodomain-like
CDDcd000861.04E-13108163No hitNo description
PfamPF059206.0E-17119158IPR008422Homeobox KN domain
PROSITE patternPS000270137160IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 182 aa     Download sequence    Send to blast
MVESLGKHLG ISLRLSLSVL EADYFCLYKG LLVAEMAVLI LEIFLALVGD EAAGSSEEDL  60
SGGETQVPEC FRAPPVEREL KDKLLRKYGG YISTLKHEFS KKKKKGKLPR EARQILLDWW  120
NLHFKWPYPT EADKLALAES TGLDQRQINN WFINQRKRHW KPSENMQFTL MDSLYGPIFM  180
NG
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:16798887}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269|PubMed:11311158, ECO:0000269|PubMed:16798887}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028068158.12e-70homeobox protein knotted-1-like 6
SwissprotQ84JS62e-56KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBLA0A067FQF22e-69A0A067FQF2_CITSI; Uncharacterized protein (Fragment)
STRINGXP_006477546.15e-70(Citrus sinensis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM8352785
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G23380.12e-58KNOTTED1-like homeobox gene 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]