PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_8133_f_4

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

NAC

Protein Properties

Length: 394aa MW: 45703.1 Da PI: 6.7024

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_8133_f_4	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	180.1	5.8e-56	16	144	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvka.eekewyfFskrdkkyatgkrknratksgyWkatgkdkevl 93 +ppGfrFhPtdeelv++yL+kk+++k+++l +vik+vd+yk+ePwdL+ k+ + e++ewyfFs++dkky+tg+r+nratk+g+Wkatg+dk+++ Neem_8133_f_4 16 VPPGFRFHPTDEELVDYYLRKKIASKRIDL-DVIKDVDLYKIEPWDLQDlcKIGTeEQNEWYFFSHKDKKYPTGTRTNRATKAGFWKATGRDKAIY 110 69**************************.9***********943455552555*********************************** PP NAM 94 skkgelvglkktLvfykgrapkgektdWvmheyrl 128 s +++l+g++ktLvfykgrap+g+k+dW+mheyr Neem_8133_f_4 111 S-RHSLIGMRKTLVFYKGRAPNGQKSDWIMHEYRH 144 .889***************************96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	9.68E-59	11	154	IPR003441	NAC domain
PROSITE profile	PS51005	57.298	16	193	IPR003441	NAC domain
Pfam	PF02365	2.6E-28	17	143	IPR003441	NAC domain
SuperFamily	SSF101941	9.68E-59	181	193	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0048759	Biological Process	xylem vessel member cell differentiation
GO:1901348	Biological Process	positive regulation of secondary cell wall biogenesis
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 394 aa Download sequence Send to blast
MQVLTPWDNM NSFSHVPPGF RFHPTDEELV DYYLRKKIAS KRIDLDVIKD VDLYKIEPWD 60 LQDLCKIGTE EQNEWYFFSH KDKKYPTGTR TNRATKAGFW KATGRDKAIY SRHSLIGMRK 120 TLVFYKGRAP NGQKSDWIMH EYRHETNENG TPQAMRTVSL KTFFSPSDFL LKHFYPEIIS 180 KEEGWVVCRV FKKRMATVRK MGEYDSSCWY DEQVSFMPEI DSPGRRMPQP FTPYHLHYPC 240 KQELELQYNM SLHDAFLQLP QLESPKVPQS AASVSCNSVV PFGYDRNNGS TLQSSTLTQE 300 EHTQQAHQQD LNSLYSNNNE QAVDQVTDWR VLDKFVASQL SHEDASKENN YSNAADFNVA 360 EQMNSILANG SKRSEIAQDY ASTSTSSCQI DLWK

Sequence ? help Back to Top

Protein Sequence Length: 394 aa Download sequence Send to blast

MQVLTPWDNM NSFSHVPPGF RFHPTDEELV DYYLRKKIAS KRIDLDVIKD VDLYKIEPWD  60
LQDLCKIGTE EQNEWYFFSH KDKKYPTGTR TNRATKAGFW KATGRDKAIY SRHSLIGMRK  120
TLVFYKGRAP NGQKSDWIMH EYRHETNENG TPQAMRTVSL KTFFSPSDFL LKHFYPEIIS  180
KEEGWVVCRV FKKRMATVRK MGEYDSSCWY DEQVSFMPEI DSPGRRMPQP FTPYHLHYPC  240
KQELELQYNM SLHDAFLQLP QLESPKVPQS AASVSCNSVV PFGYDRNNGS TLQSSTLTQE  300
EHTQQAHQQD LNSLYSNNNE QAVDQVTDWR VLDKFVASQL SHEDASKENN YSNAADFNVA  360
EQMNSILANG SKRSEIAQDY ASTSTSSCQI DLWK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	2e-47	15	143	14	139	Stress-induced transcription factor NAC1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, genes driven by the secondary wall NAC binding element (SNBE). Triggers thickening of secondary walls (PubMed:16103214, PubMed:25148240). {ECO:0000250\|UniProtKB:Q9LVA1, ECO:0000269\|PubMed:16103214, ECO:0000269\|PubMed:25148240}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00136	DAP	Transfer from AT1G12260	Download

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KC775296	9e-92	KC775296.1 Jatropha curcas NAC transcription factor 018 gene, complete cds.
GenBank	KR605203	9e-92	KR605203.1 Manihot esculenta NAC transcription factors 65 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017973363.1	0.0	PREDICTED: NAC domain-containing protein 7
Swissprot	Q9FWX2	1e-158	NAC7_ARATH; NAC domain-containing protein 7
TrEMBL	A0A061GBJ7	0.0	A0A061GBJ7_THECC; NAC domain protein, IPR003441 isoform 1
STRING	EOY24430	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2111	26	78

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G12260.1	1e-155	NAC 007

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469]