PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Niben101Scf00565g00012.1
Organism
Nicotiana benthamiana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family bHLH
Protein Properties Length: 687aa    MW: 77072.3 Da    PI: 8.0676
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Niben101Scf00565g00012.1genomeBTI-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH35.41.9e-11434477452
                               HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHH CS
                       HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIk 52 
                               +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI 
  Niben101Scf00565g00012.1 434 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYIT 477
                               799***********************66......***************6 PP
2HLH38.12.8e-12520566455
                               HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                       HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                               +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI ++q
  Niben101Scf00565g00012.1 520 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYITEMQ 566
                               799***********************66......***************9998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142157.5E-5648236IPR025610Transcription factor MYC/MYB N-terminal
SuperFamilySSF474591.24E-14429479IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088816.196430479IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.2E-13433478IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000836.17E-11433476No hitNo description
PfamPF000106.8E-9434477IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.1E-12436485IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088816.475516565IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474592.09E-17519578IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.12E-12519570No hitNo description
PfamPF000109.2E-10520566IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.103.2E-17520577IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.5E-16522571IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 687 aa     Download sequence    Send to blast
MGTGNMSWSD EDKAMVAAVL GKEAFEYLIS SSVSAECSLM AIGNDQNLQN KLSDLVERPN  60
ATNFSWNYAI FWQISRSKSG ELVLGWGDGC CREPKEGEEC EVKRIFNLCL EDEAQQRMRK  120
RVLQKLHMLF GGTDEDNYAI GLDRVTDTEM FFLASMYFSF PRGEGGPGKC FGSGKHLWLS  180
DALKSPLNYC ARSFLAKSAG MQTIVLIPTD VGVVELGSVR SIPESLELLQ SIKSCFSSFL  240
VRAKQAACIA VVTEKKDGNN SSFLSSAFSE RPDGTPKIFG HDLNSGTHFR EKLAVRKAEE  300
RPWDIYPNGN RMPFMNGRNG LHAASWTQFS NVKPVKPVEL YRPQTPPAHN LQELVNGGRE  360
EFHLNNFQHQ KPVRMQIDFT GATSRPVISP SHTVESEHSD VEASCKEDRV GLVDEKRPRK  420
RGRKPANGRE EPLNHVEAER QRREKLNQRF YALRAVVPNI SKMDKASLLG DAIAYITEXT  480
LLSLSIQMLK LREDRVGLVD EKRPRKRGRK PANGREEPLN HVEAERQRRE KLNQRFYALR  540
AVVPNISKMD KASLLGDAIA YITEMQKKLR DMESERELRL GSTSRDAMAA EDSPNSEIQI  600
QGPDINIEAA NDEVIVRVSC PLEIHPISRV IQTFKEAQIN VVESKLSAGN GTVFHTFLLK  660
SSGSEQLTKE KLLAALSSES DSLRQFS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A1e-28428576264Transcription factor MYC2
5gnj_B1e-28428576264Transcription factor MYC2
5gnj_E1e-28428576264Transcription factor MYC2
5gnj_F1e-28428576264Transcription factor MYC2
5gnj_G1e-28428576264Transcription factor MYC2
5gnj_I1e-28428576264Transcription factor MYC2
5gnj_M1e-28428576264Transcription factor MYC2
5gnj_N1e-28428576264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1501509KRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009781532.10.0PREDICTED: transcription factor bHLH13-like
RefseqXP_016459177.10.0PREDICTED: transcription factor bHLH13-like
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A1S3Z4N70.0A0A1S3Z4N7_TOBAC; transcription factor bHLH13-like
TrEMBLA0A1U7WNL80.0A0A1U7WNL8_NICSY; transcription factor bHLH13-like
STRINGXP_009781532.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA35852348
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.31e-172bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]