PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Niben101Scf01166g16008.1
Organism
Nicotiana benthamiana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family NAC
Protein Properties Length: 301aa    MW: 34795.9 Da    PI: 6.1774
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Niben101Scf01166g16008.1genomeBTI-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM172.11.8e-5371351128
                       NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk...kvkaeekewyfFskrdkkyatgkrknratksgy 82 
                               +ppGfrFhPt+eelv +yLk+k+++ k++l +vi+++d+y++ePwd++    + ++ee+ewyfFs++d+ky++g+r+nrat++g+
  Niben101Scf01166g16008.1   7 VPPGFRFHPTEEELVGYYLKRKISSLKIDL-DVITDIDLYRMEPWDIQDrckQGYEEENEWYFFSHKDRKYPSGTRTNRATAAGF 90 
                               69****************************.9***************952333344778************************** PP

                       NAM  83 WkatgkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128
                               Wkatg+dk+vls k++ +g++ktLvfy+grap+g+k+dW+mheyrl
  Niben101Scf01166g16008.1  91 WKATGRDKAVLS-KEKIIGMRKTLVFYTGRAPNGKKSDWIMHEYRL 135
                               ************.9999***************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019411.83E-594156IPR003441NAC domain
PROSITE profilePS5100558.2167156IPR003441NAC domain
PfamPF023651.1E-288135IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 301 aa     Download sequence    Send to blast
MEMESCVPPG FRFHPTEEEL VGYYLKRKIS SLKIDLDVIT DIDLYRMEPW DIQDRCKQGY  60
EEENEWYFFS HKDRKYPSGT RTNRATAAGF WKATGRDKAV LSKEKIIGMR KTLVFYTGRA  120
PNGKKSDWIM HEYRLQTSQH GPPQEEGWVV CRAFKKPTPN NNPSLDSWKN ACANYNCIRG  180
TNTSYGPPSE LPSPMHYNPF NQTTNLNHQF PFNPSLHHHQ DLISSQIIGF ENQLIELPQL  240
DSPTISTSMA THEEDKNSYG SNCQFFDMIE APSSSYSFPN LPLVDDDQNR MSQLLQCYPD  300
L
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A7e-49715617165NO APICAL MERISTEM PROTEIN
1ut4_B7e-49715617165NO APICAL MERISTEM PROTEIN
1ut7_A7e-49715617165NO APICAL MERISTEM PROTEIN
1ut7_B7e-49715617165NO APICAL MERISTEM PROTEIN
3swm_A6e-49715620168NAC domain-containing protein 19
3swm_B6e-49715620168NAC domain-containing protein 19
3swm_C6e-49715620168NAC domain-containing protein 19
3swm_D6e-49715620168NAC domain-containing protein 19
3swp_A6e-49715620168NAC domain-containing protein 19
3swp_B6e-49715620168NAC domain-containing protein 19
3swp_C6e-49715620168NAC domain-containing protein 19
3swp_D6e-49715620168NAC domain-containing protein 19
4dul_A7e-49715617165NAC domain-containing protein 19
4dul_B7e-49715617165NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (e.g. genes involved in secondary wall biosynthesis, cell wall modification such as xylan accumulation, and programmed cell death) (PubMed:20935069, PubMed:20488898, PubMed:22037706, PubMed:21284754). Involved in xylem formation in roots and shoots, especially regulating protoxylem vessel differentiation by promoting immature xylem vessel-specific genes expression (PubMed:16103214, PubMed:18445131, PubMed:20488898, PubMed:21498679, PubMed:21284754). Can activate the expression of several genes including XCP1, MYB46, NAC010/SND3, MYB103, MYB58, MYB63, MYB83, KNAT7, ASL19 and ASL20 (PubMed:17890373, PubMed:19088331, PubMed:18952777, PubMed:19122102, PubMed:19808805, PubMed:20935069, PubMed:21284754). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:17890373, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:18952777, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:19122102, ECO:0000269|PubMed:19808805, ECO:0000269|PubMed:20488898, ECO:0000269|PubMed:20935069, ECO:0000269|PubMed:21284754, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22037706}.; FUNCTION: Required for the soilborne fungal pathogen Verticillium longisporum-induced transdifferentiation of chloroplast-containing bundle sheath cells to functional xylem elements leading to stunted growth, vein clearing, and leaf chloroses, as well as xylem hyperplasia within the vasculature of leaves, hypocotyls, and roots due to reinitiation of cambial activity and transdifferentiation of xylem parenchyma cells. This developmental reprogramming mediates also an increased drought stress tolerance. {ECO:0000269|PubMed:23023171}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By brassinosteroids (e.g. brassinolide BL), auxin (e.g. 2,4-dichlorphenoxyacetic acid 2,4-D) and cytokinin (e.g. kinetin), with a synergistic effect (PubMed:16103214, PubMed:22345435). Up-regulated in a feed-back loop by ASL20 (PubMed:19088331). Levels are monitored by proteasome-mediated degradation (PubMed:18445131). Repressed by WEE1 upon replication stress to prevent premature tracheary element differentiation (PubMed:21498679). Accumulates during infection by the soilborne fungal pathogen Verticillium longisporum, especially in tissues undergoing de novo xylem formation (PubMed:23023171). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22345435, ECO:0000269|PubMed:23023171}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009774570.10.0PREDICTED: NAC domain-containing protein 7-like
RefseqXP_016440678.10.0PREDICTED: NAC domain-containing protein 30-like
SwissprotQ9C8W91e-106NAC30_ARATH; NAC domain-containing protein 30
TrEMBLA0A1S3XL810.0A0A1S3XL81_TOBAC; NAC domain-containing protein 30-like
TrEMBLA0A1U7WJY30.0A0A1U7WJY3_NICSY; NAC domain-containing protein 7-like
STRINGXP_009774570.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA13424297
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G71930.11e-109vascular related NAC-domain protein 7
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Kakehi J, et al.
    Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana.
    PLoS ONE, 2015. 10(1): p. e0117309
    [PMID:25625317]
  3. Li Z, et al.
    A Transcriptional and Metabolic Framework for Secondary Wall Formation in Arabidopsis.
    Plant Physiol., 2016. 172(2): p. 1334-1351
    [PMID:27566165]
  4. de Lucas M, et al.
    Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation.
    Plant Cell, 2016. 28(10): p. 2616-2631
    [PMID:27650334]
  5. Tan TT, et al.
    Transcription Factors VND1-VND3 Contribute to Cotyledon Xylem Vessel Formation.
    Plant Physiol., 2018. 176(1): p. 773-789
    [PMID:29133368]
  6. Ohashi-Ito K,Iwamoto K,Fukuda H
    LOB DOMAIN-CONTAINING PROTEIN 15 Positively Regulates Expression of VND7, a Master Regulator of Tracheary Elements.
    Plant Cell Physiol., 2018. 59(5): p. 989-996
    [PMID:29444288]