PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Niben101Scf04319g00001.1

Organism

Nicotiana benthamiana

Taxonomic ID

4100

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

WRKY

Protein Properties

Length: 569aa MW: 61518.9 Da PI: 6.3475

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf04319g00001.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	78.7	6.3e-25	309	363	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 Dg++WrKYGqK+ kg+++pr+YYrCt+a gCpv +r+aed +++++tYeg+Hnh+ Niben101Scf04319g00001.1 309 TDGCQWRKYGQKMAKGNPCPRAYYRCTMAaGCPV----QRCAEDRTILITTYEGTHNHP 363 7*************************9995....67999***************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	2.4E-27	293	365	IPR003657	WRKY domain
SuperFamily	SSF118290	4.05E-23	301	365	IPR003657	WRKY domain
PROSITE profile	PS50811	24.283	303	365	IPR003657	WRKY domain
SMART	SM00774	1.5E-29	308	364	IPR003657	WRKY domain
Pfam	PF03106	6.3E-21	310	363	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 569 aa Download sequence Send to blast
MASGSGLSFD PDPIKHFLQP KKLFNLLTSM ESSPYKNRSP PSTIQFPVNL NCSNTDHNQE 60 EEEEEQKIRP VIDEMDFFAD HKKDGSNSEE AATTANDTAT GLHLLTANTY SDQSIVDDGL 120 SPNSEDKRTK NELAVLQAEL ERMNGENRRL KDMLNQATNN YSNLHIKMMT IIQQQQHQEN 180 DQHDGKSEEV RHQIHSKNGH GGGGQIVPRQ FMDLGLAAAT GSEAEETSLS SSEGRSGRDK 240 SRSPPNNMES GSTCGIGRED SPDKGSPGWG PNKIPRLGNG SKSTDQATEA TMRKARVSVR 300 ARSEAPMITD GCQWRKYGQK MAKGNPCPRA YYRCTMAAGC PVQRCAEDRT ILITTYEGTH 360 NHPLPPAAMA MASTTSSAAR MLLSGSMPSA DGLMNSNFFA RTLLPCSSSM ATISASAPFP 420 TVTLDLTQSP NPLQFPRPPN QFQVPFSNPP HNMLSNPAAL LPQIFNQALY NQSKFSGLQL 480 SQDSEGQNPS TLPSSIHQSN HNPLADTVNA LTADPNFTAA LAAAITSLIG NPQQPNNGST 540 NNTTSIAMTA NNQNSSVTTN GNNTSNGNQ

Sequence ? help Back to Top

Protein Sequence Length: 569 aa Download sequence Send to blast

MASGSGLSFD PDPIKHFLQP KKLFNLLTSM ESSPYKNRSP PSTIQFPVNL NCSNTDHNQE  60
EEEEEQKIRP VIDEMDFFAD HKKDGSNSEE AATTANDTAT GLHLLTANTY SDQSIVDDGL  120
SPNSEDKRTK NELAVLQAEL ERMNGENRRL KDMLNQATNN YSNLHIKMMT IIQQQQHQEN  180
DQHDGKSEEV RHQIHSKNGH GGGGQIVPRQ FMDLGLAAAT GSEAEETSLS SSEGRSGRDK  240
SRSPPNNMES GSTCGIGRED SPDKGSPGWG PNKIPRLGNG SKSTDQATEA TMRKARVSVR  300
ARSEAPMITD GCQWRKYGQK MAKGNPCPRA YYRCTMAAGC PVQRCAEDRT ILITTYEGTH  360
NHPLPPAAMA MASTTSSAAR MLLSGSMPSA DGLMNSNFFA RTLLPCSSSM ATISASAPFP  420
TVTLDLTQSP NPLQFPRPPN QFQVPFSNPP HNMLSNPAAL LPQIFNQALY NQSKFSGLQL  480
SQDSEGQNPS TLPSSIHQSN HNPLADTVNA LTADPNFTAA LAAAITSLIG NPQQPNNGST  540
NNTTSIAMTA NNQNSSVTTN GNNTSNGNQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	2e-18	295	367	1	76	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the control of processes related to senescence and pathogen defense (PubMed:12000796). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:12000796). Activates the transcription of the SIRK gene and represses its own expression and that of the WRKY42 genes (PubMed:12000796). Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression (PubMed:25733771). {ECO:0000269\|PubMed:12000796, ECO:0000269\|PubMed:25733771}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid, ethylene, jasmonic acid, pathogens, wounding and strongly during leaf senescence. {ECO:0000269\|PubMed:11449049, ECO:0000269\|PubMed:11722756}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009804478.1	0.0	PREDICTED: probable WRKY transcription factor 42
Refseq	XP_016445607.1	0.0	PREDICTED: probable WRKY transcription factor 42
Refseq	XP_019249656.1	0.0	PREDICTED: WRKY transcription factor 42-like
Swissprot	Q9C519	1e-133	WRKY6_ARATH; WRKY transcription factor 6
TrEMBL	A0A1J6I7B3	0.0	A0A1J6I7B3_NICAT; Wrky transcription factor 6
TrEMBL	A0A1S3Y0V2	0.0	A0A1S3Y0V2_TOBAC; probable WRKY transcription factor 42
TrEMBL	A0A1U7YN04	0.0	A0A1U7YN04_NICSY; probable WRKY transcription factor 42
STRING	XP_009804478.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA945	24	92

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G62300.1	1e-112	WRKY family protein

Publications ? help Back to Top
Zhou F, et al. High humidity suppresses ssi4-mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression. Plant J., 2004. 39(6): p. 920-32 [PMID:15341634] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P An extracellular subtilase switch for immune priming in Arabidopsis. PLoS Pathog., 2013. 9(6): p. e1003445 [PMID:23818851] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Singh V,Roy S,Singh D,Nandi AK Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes. J. Biosci., 2014. 39(1): p. 119-26 [PMID:24499796] Ali MA,Wieczorek K,Kreil DP,Bohlmann H The beet cyst nematode Heterodera schachtii modulates the expression of WRKY transcription factors in syncytia to favour its development in Arabidopsis roots. PLoS ONE, 2014. 9(7): p. e102360 [PMID:25033038] Chai J,Liu J,Zhou J,Xing D Mitogen-activated protein kinase 6 regulates NPR1 gene expression and activation during leaf senescence induced by salicylic acid. J. Exp. Bot., 2014. 65(22): p. 6513-28 [PMID:25210078] Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress. Plant Cell, 2014. 26(12): p. 4656-79 [PMID:25549671] Xiao D, et al. SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis. Plant Physiol., 2015. 169(2): p. 1275-91 [PMID:26304848] Bakshi M, et al. WRKY6 restricts Piriformospora indica-stimulated and phosphate-induced root development in Arabidopsis. BMC Plant Biol., 2015. 15: p. 305 [PMID:26718529] Huang Y,Feng CZ,Ye Q,Wu WH,Chen YF Arabidopsis WRKY6 Transcription Factor Acts as a Positive Regulator of Abscisic Acid Signaling during Seed Germination and Early Seedling Development. PLoS Genet., 2016. 12(2): p. e1005833 [PMID:26829043] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P Correction: An Extracellular Subtilase Switch for Immune Priming in Arabidopsis. PLoS Pathog., 2016. 12(11): p. e1006003 [PMID:27806116] Li H, et al. BZR1 Positively Regulates Freezing Tolerance via CBF-Dependent and CBF-Independent Pathways in Arabidopsis. Mol Plant, 2017. 10(4): p. 545-559 [PMID:28089951] Stetter MG,Benz M,Ludewig U Increased root hair density by loss of WRKY6 in Arabidopsis thaliana. PeerJ, 2017. 5: p. e2891 [PMID:28149680] Zhou X, et al. StMYB44 negatively regulates phosphate transport by suppressing expression of PHOSPHATE1 in potato. J. Exp. Bot., 2017. 68(5): p. 1265-1281 [PMID:28338870] Bakshi M, et al. Piriformospora indica Reprograms Gene Expression in Arabidopsis Phosphate Metabolism Mutants But Does Not Compensate for Phosphate Limitation. Front Microbiol, 2017. 8: p. 1262 [PMID:28747898] Zhang Y, et al. DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6. Plant Cell Rep., 2018. 37(7): p. 981-992 [PMID:29574486]