PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Niben101Scf04407g01012.1

Organism

Nicotiana benthamiana

Taxonomic ID

4100

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

WRKY

Protein Properties

Length: 536aa MW: 59151.8 Da PI: 6.589

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf04407g01012.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.7	3.1e-30	249	308	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a +Cpv+k+v+r+ ed +++++tYeg+Hnh+ Niben101Scf04407g01012.1 249 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApSCPVRKQVQRCMEDMSILITTYEGTHNHP 308 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	5.1E-31	234	308	IPR003657	WRKY domain
SuperFamily	SSF118290	5.36E-27	242	309	IPR003657	WRKY domain
PROSITE profile	PS50811	27.152	244	310	IPR003657	WRKY domain
SMART	SM00774	6.1E-36	249	309	IPR003657	WRKY domain
Pfam	PF03106	1.0E-26	250	308	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0006952	Biological Process	defense response
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 536 aa Download sequence Send to blast
MEAAFRKSIN GGLIKEEKSN KLADQSSSYE EGFIEDSNVL KVGKEREVHE DDNSKSPQQK 60 HIDSDKEDDQ LESVKADMKE VMEENQRLKM HLDRIMKDYR KLQMQFHDIV QKDHTEKSNS 120 ININTRHDEC DKADQLISLS LGRTSSDTKK EELSKIMSKD KAEEEDNKGG LTLGLDCKFD 180 LSVKTTLTES STANISEENS SEEVKDEKGE TWPPHKILKT MRNGEDDTQL NPSKRAKVSV 240 RVRCDAPTMN DGCQWRKYGQ KIAKGNPCPR AYYRCTVAPS CPVRKQVQRC MEDMSILITT 300 YEGTHNHPLS LSATSMAFTT SAAASMLLSG SSSTSESGSN PPATNTTNTN GLNFYLSDSS 360 KPKPFYLQNS SISSSSSPPT ITLDLTSSSS TPNHNRMSSN YLPRYNSSTN ILNFSSLESN 420 PLLPMSWSNG AYNKNQEISS LSFAKRPQEN IFQSYLQNNI SAKPAQTLLP QDTIAAATKA 480 ITSDPNFQSA LAVALTSIIG SGGGNHAGGI EEKSGQNLKV TEPFPVLCSF PSTSKK

Sequence ? help Back to Top

Protein Sequence Length: 536 aa Download sequence Send to blast

MEAAFRKSIN GGLIKEEKSN KLADQSSSYE EGFIEDSNVL KVGKEREVHE DDNSKSPQQK  60
HIDSDKEDDQ LESVKADMKE VMEENQRLKM HLDRIMKDYR KLQMQFHDIV QKDHTEKSNS  120
ININTRHDEC DKADQLISLS LGRTSSDTKK EELSKIMSKD KAEEEDNKGG LTLGLDCKFD  180
LSVKTTLTES STANISEENS SEEVKDEKGE TWPPHKILKT MRNGEDDTQL NPSKRAKVSV  240
RVRCDAPTMN DGCQWRKYGQ KIAKGNPCPR AYYRCTVAPS CPVRKQVQRC MEDMSILITT  300
YEGTHNHPLS LSATSMAFTT SAAASMLLSG SSSTSESGSN PPATNTTNTN GLNFYLSDSS  360
KPKPFYLQNS SISSSSSPPT ITLDLTSSSS TPNHNRMSSN YLPRYNSSTN ILNFSSLESN  420
PLLPMSWSNG AYNKNQEISS LSFAKRPQEN IFQSYLQNNI SAKPAQTLLP QDTIAAATKA  480
ITSDPNFQSA LAVALTSIIG SGGGNHAGGI EEKSGQNLKV TEPFPVLCSF PSTSKK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	5e-19	249	309	14	73	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009616443.1	0.0	PREDICTED: probable WRKY transcription factor 61
Swissprot	A0A3Q7GFB5	0.0	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A1S4B0U8	0.0	A0A1S4B0U8_TOBAC; probable WRKY transcription factor 61
STRING	XP_009616443.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1945	24	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	1e-64	WRKY DNA-binding protein 72

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]