PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Niben101Scf10866g02011.1
Common NameNbWRKY14
Organism
Nicotiana benthamiana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family WRKY
Protein Properties Length: 512aa    MW: 56338 Da    PI: 6.9975
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Niben101Scf10866g02011.1genomeBTI-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY96.61.7e-30227282359
                               -SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                      WRKY   3 DgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                               DgynWrKYGqK+vk se+prsYY+Ct+ +Cpvkkkve s  d++++eitY+g+Hnhe
  Niben101Scf10866g02011.1 227 DGYNWRKYGQKMVKASECPRSYYKCTHLKCPVKKKVELSI-DGHITEITYKGHHNHE 282
                               9***************************************.***************7 PP
2WRKY1054e-33398456159
                               ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                      WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                               ldDg++WrKYGqK+vkg+++prsYYrCt++gC+v+k+ver++ dpk+v++tYeg+Hnh+
  Niben101Scf10866g02011.1 398 LDDGFKWRKYGQKVVKGNHHPRSYYRCTYPGCNVRKHVERASADPKAVITTYEGKHNHN 456
                               59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.801.3E-26221284IPR003657WRKY domain
SuperFamilySSF1182904.18E-24224284IPR003657WRKY domain
SMARTSM007742.5E-32225283IPR003657WRKY domain
PfamPF031061.7E-22227282IPR003657WRKY domain
PROSITE profilePS5081121.631227284IPR003657WRKY domain
Gene3DG3DSA:2.20.25.804.0E-36384458IPR003657WRKY domain
SuperFamilySSF1182901.83E-29390458IPR003657WRKY domain
PROSITE profilePS5081135.508393458IPR003657WRKY domain
SMARTSM007741.5E-39398457IPR003657WRKY domain
PfamPF031061.0E-25399455IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 512 aa     Download sequence    Send to blast
MGEKFKASAV SELTIPPRAP NFEAFFGGGN MPYFSPGPMT LVSSFFSESE YPSFSQLLAG  60
AMASPLAKPP TLLPENSSGE ENCKEGNQKN LGYKQNRPMG LMVAQDSPLF MIPTGLSPSG  120
LLNSPGFLSP LQSPFGMSHQ QALAHVTAQA ALSQSYLQTQ AEYHFSSQGT SAQVLGNETL  180
TEPTESSLQP QLDAMPSDQQ NNKIELPLVS QSEDKPSFAS VDRPACDGYN WRKYGQKMVK  240
ASECPRSYYK CTHLKCPVKK KVELSIDGHI TEITYKGHHN HELPQPSRRR RDSCAQDGSD  300
CSKAKPESKM QSGTEVNGLN GALPACSGQV SSEMASRLLS NECDEIEDTA TAAEEGHDDE  360
PNVKRMKTAV EAPNLVSSHK AVSESKIVVQ TRSEVDILDD GFKWRKYGQK VVKGNHHPRS  420
YYRCTYPGCN VRKHVERASA DPKAVITTYE GKHNHNIPIA RNRSHGTAQD STRQLNEQDV  480
ATWRPSLHEN VAFHNNNEIP VCRQLKEEQI AA
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A3e-36227458877Probable WRKY transcription factor 4
2lex_A3e-36227458877Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Has a positive role in resistance to necrotrophic pathogens (e.g. Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e.g. Pseudomonas syringae). {ECO:0000269|PubMed:18570649, ECO:0000269|PubMed:22219184}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By biotic and abiotic stresses such as pathogen infection (e.g. Botrytis cinerea and Pseudomonas syringae), salicylic acid (SA), jasmonic acid (JA), ethylene (ACC), liquid infiltration or spraying, and strongly during leaf senescence. {ECO:0000269|PubMed:11449049, ECO:0000269|PubMed:11722756, ECO:0000269|PubMed:18570649}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016461958.10.0PREDICTED: probable WRKY transcription factor 3
SwissprotQ9XI901e-126WRKY4_ARATH; Probable WRKY transcription factor 4
TrEMBLA0A0P0UVQ80.0A0A0P0UVQ8_NICBE; Transcription factor
STRINGXP_009768106.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA43142344
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G13960.11e-116WRKY DNA-binding protein 4
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Adachi H, et al.
    WRKY Transcription Factors Phosphorylated by MAPK Regulate a Plant Immune NADPH Oxidase in Nicotiana benthamiana.
    Plant Cell, 2015. 27(9): p. 2645-63
    [PMID:26373453]
  4. Aamir M, et al.
    Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach.
    Front Plant Sci, 2017. 8: p. 819
    [PMID:28611792]