PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Oropetium_20150105_23835A

Organism

Oropetium thomaeum

Taxonomic ID

1148796

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Cynodonteae; Tripogoninae; Oropetium

Family

E2F/DP

Protein Properties

Length: 220aa MW: 25261.8 Da PI: 4.9747

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Oropetium_20150105_23835A	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	87	1.4e-27	20	85	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL llt+kf++l+e++e+g+++ln++a++L +v ++RRiYDi+NVLe+++liek+ kn irwkg Oropetium_20150105_23835A 20 RYDSSLSLLTKKFVSLFEEAEDGTIDLNKAAESL---EV--QKRRIYDITNVLEGVDLIEKTLKNMIRWKG 85 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.7E-29	16	86	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	2.72E-17	20	83	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	6.0E-34	20	85	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	5.9E-25	22	85	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF144074	3.92E-27	97	206	No hit	No description
CDD	cd14660	1.21E-34	97	206	No hit	No description
Pfam	PF16421	1.8E-27	101	206	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 220 aa Download sequence Send to blast
MTRDHQLGEG GSLYSSNHCR YDSSLSLLTK KFVSLFEEAE DGTIDLNKAA ESLEVQKRRI 60 YDITNVLEGV DLIEKTLKNM IRWKGFDISK PKEKEHQTSA LKEELESLYE EDDRLENEIR 120 KAQEKLEDLT LDEDKRKLLY VLKDDINNIP HFKGQTLIAI NAPRGTSIEV PDPDADFYLF 180 GKLKSTEKHY RMVLRSSMGP IDCYLIRLAL ISMSIVETM*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	1e-22	19	86	6	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Oropetium_20150105_23835A

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_025824426.1	1e-107	transcription factor E2FB-like isoform X1
Refseq	XP_025824427.1	1e-107	transcription factor E2FB-like isoform X2
Swissprot	Q9FV71	8e-73	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A2S3I510	1e-105	A0A2S3I510_9POAL; Uncharacterized protein
TrEMBL	A0A2T7CRZ0	1e-105	A0A2T7CRZ0_9POAL; Uncharacterized protein
TrEMBL	A0A2T8IAJ8	1e-105	A0A2T8IAJ8_9POAL; Uncharacterized protein
STRING	OS04T0112200-00	1e-100	(Oryza sativa)
STRING	GRMZM2G050590_P01	1e-100	(Zea mays)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP625	37	148

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.2	3e-75	E2F transcription factor 1

Link Out ? help Back to Top
Phytozome	Oropetium_20150105_23835A

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]