PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ote100200850061
Organism
Ocimum tenuiflorum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ocimum
Family HD-ZIP
Protein Properties Length: 706aa    MW: 78550.4 Da    PI: 6.984
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ote100200850061genomeOteDB-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.45.9e-191570156
                                  TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
                      Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                                  +++ +++t++q+++Le++F+++ +p++++r +L+++l+L  rq+k+WFqNrR+++k
  Ote100200850061|100200850061 15 KKRYHRHTANQIQRLESMFKECAHPDEKTRNQLSRELNLHPRQIKFWFQNRRTQMK 70
                                  678899***********************************************998 PP
2START1341.7e-4226643944206
                                   CEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEE CS
                         START  44 sgealrasgvvdmvlallveellddkeqWdetla....kaetlevissg......galqlmvaelqalsplvp.RdfvfvR 113
                                   ++ea+r+s v   +   lv  ++d + +W e ++    +a t+ev+s g      g lqlm+ elq+ls lvp R+ +f+R
  Ote100200850061|100200850061 266 RIEASRDSQVFVLNDLALVDMFVDAN-KWMELFPaivaRARTIEVLSCGmlgshsGSLQLMYGELQMLSALVPtRKLYFLR 345
                                   6899***9988877777*********.******99999******************************************* PP

                                   EEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHH CS
                         START 114 yirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvdlkgrlp.hwllrslvksglaega 193
                                   + +q +ag+w++vdvS d +++ ++  s+ +a+llpSg+lie+++ng+skvtwveh+ +++++  h l+r lv+sgla+ga
  Ote100200850061|100200850061 346 FVQQIEAGSWAVVDVSYDFPNQDSQFNSSCKAHLLPSGCLIEEMPNGYSKVTWVEHWAVEEKTAvHRLYRELVHSGLAFGA 426
                                   **********************99989999*******************************9988**************** PP

                                   HHHHHHTXXXXXX CS
                         START 194 ktwvatlqrqcek 206
                                    +w+a lqr ce+
  Ote100200850061|100200850061 427 ERWLANLQRMCER 439
                                   ***********97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466895.85E-19875IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.2E-201077IPR009057Homeodomain-like
PROSITE profilePS5007117.2651272IPR001356Homeobox domain
SMARTSM003897.1E-181376IPR001356Homeobox domain
CDDcd000866.11E-181473No hitNo description
PfamPF000461.8E-161570IPR001356Homeobox domain
PROSITE patternPS0002704770IPR017970Homeobox, conserved site
SMARTSM002342.8E-22236439IPR002913START domain
CDDcd088755.69E-86255438No hitNo description
PfamPF018525.2E-35266439IPR002913START domain
SuperFamilySSF559612.71E-24281440No hitNo description
PROSITE profilePS5084832.542283442IPR002913START domain
Gene3DG3DSA:3.30.530.201.1E-5309439IPR023393START-like domain
SuperFamilySSF559619.42E-20459698No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 706 aa     Download sequence    Send to blast
MEFSGGHHDA SDRRKKRYHR HTANQIQRLE SMFKECAHPD EKTRNQLSRE LNLHPRQIKF  60
WFQNRRTQMK AQHERADNCT LRADNDRIRC ENIAMREALR NVICPSCGGP PVSEDSYFDE  120
QKLRIENAQL KEELDRVSSI AAKYIGRPIS QLPPVQPIHV SSLDLSMSTF GGHVMPLPSL  180
DLDLLPGSSL GVPSNLSFPT ITISDVDKSL MADMATAXXX XXXXXXXXXX XXXXXXXXXX  240
XXXXXXXXXX XXXPRPNSHL KNPGIRIEAS RDSQVFVLND LALVDMFVDA NKWMELFPAI  300
VARARTIEVL SCGMLGSHSG SLQLMYGELQ MLSALVPTRK LYFLRFVQQI EAGSWAVVDV  360
SYDFPNQDSQ FNSSCKAHLL PSGCLIEEMP NGYSKVTWVE HWAVEEKTAV HRLYRELVHS  420
GLAFGAERWL ANLQRMCERI ACLMVAANSN RELGAVPSPE GTRSMMKLAQ RMVNNFCASI  480
NPSSGQHLTT LLGSSELEVR ATLHRSIDPG QPNRMVLSAA ATIWLPVPPQ NVFNFFRDER  540
TRPQWDVLSN QNPVHEVAHI ANGSYSGNCI SVLRALNTSQ NNMLILQESC LDSSGCLVVY  600
CPVDLPSINI AMSGEDTSFI PLLPSGFTIS PDGSRPDHFH VGGGDGASTS SNVDKSSTGS  660
LVTVVFQILV SNMPTARISP ETVNTVNNLI SNTIHQIKAA MNCSPS
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011072039.10.0homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A4D8YQW40.0A0A4D8YQW4_SALSN; Homeobox-leucine zipper protein
STRINGMigut.O00242.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]