PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ote100225360121
Organism
Ocimum tenuiflorum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ocimum
Family E2F/DP
Protein Properties Length: 390aa    MW: 43706.7 Da    PI: 8.061
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ote100225360121genomeOteDB-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP73.91.8e-2391156171
                       E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                                   rk+ksL+ll+++fl+l+ +   +++ l+++a++L    v  +rRRiYDi+NVLe+++++++kekn+++wkg
  Ote100225360121|100225360121  91 RKQKSLGLLCSNFLSLYDRDGVEVIGLDDAASRL---GV--ERRRIYDIVNVLESVGILTRKEKNRYTWKG 156
                                   79*****************999************...**..****************************98 PP
2E2F_TDP36.48.5e-122142504071
                       E2F_TDP  40 knkrRRiYDilNVLealnliek.....kekneirwkg 71 
                                   k k+RR+YDi+NVL++++ iek     ++k+++rw g
  Ote100225360121|100225360121 214 KPKVRRLYDIANVLSSMKFIEKthhpdTRKPAFRWTG 250
                                   5689**********************99*******97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.108.6E-2789157IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.27E-1691154IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.0E-2891156IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.8E-2092156IPR003316E2F/DP family, winged-helix DNA-binding domain
SMARTSM013726.7E-6159250IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.86E-7196251IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023192.3E-9214250IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.6E-11215251IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 390 aa     Download sequence    Send to blast
MEIQTPALFA WRIFKLSKSL SNSQTLIPAI PNKPLLYGLA SIHTDLPFSW CGFVRTISCL  60
SLYQEIDLKE EMALPSMHAT DSGSKDMPYC RKQKSLGLLC SNFLSLYDRD GVEVIGLDDA  120
ASRLGVERRR IYDIVNVLES VGILTRKEKN RYTWKGFGAI PKALEDLKKE GLRENVPADT  180
SCSEKISDDE EDEMCSDMNS LSQNDRSDSG SVPKPKVRRL YDIANVLSSM KFIEKTHHPD  240
TRKPAFRWTG LGGKPDNISV GSLISSDSKR IFGTDLTNAA MKRLKVDEGK FQVLKPHNQV  300
QVKHEKENED ESIAAAKNYQ FGPFAPASVP KVGDSHDRKG KQAVDWESLA SSYRPQYHNQ  360
ALKDLFSHFV DAWKSWCSEV AGKGPVQLIS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-1691171488Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011071778.11e-164E2F transcription factor-like E2FE isoform X2
SwissprotQ8LSZ41e-84E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A4D9A1231e-179A0A4D9A123_SALSN; Transcription factor E2F7/8
STRINGMigut.I00063.1.p1e-155(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA25222457
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]