PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PEQU_05089
Organism
Phalaenopsis equestris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; Asparagales; Orchidaceae; Epidendroideae; Vandeae; Aeridinae; Phalaenopsis
Family E2F/DP
Protein Properties Length: 390aa    MW: 43846.9 Da    PI: 8.6849
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PEQU_05089genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP75.65e-241681171
     E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                rk+ksL+ll+++f++l++k + ++v+l+++a +L    v  +rRRiYDi+NV+e+++++++k+kn++ w+g
  PEQU_05089 16 RKQKSLGLLCSNFVSLYNKDDVETVCLDDAAMKL---GV--ERRRIYDIVNVMESIGVLTRKAKNRYLWIG 81
                79*****************999************...**..****************************98 PP
2E2F_TDP78.18.2e-25157237171
     E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                 rkeksL++ltq+f+kll +s++++v+l+e+ak L+ +      +++k+RR+YDi+NVL++lnliek     ++k+++rw g
  PEQU_05089 157 RKEKSLGQLTQNFVKLLLSSNAEMVSLDEAAKLLLGDgqnpsYMRTKVRRLYDIANVLSSLNLIEKthqsdTRKPAFRWLG 237
                 79****************************************9*************************9999*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.108.4E-261283IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.9E-151580IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.6E-281681IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023195.8E-211781IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.7E-24156238IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.6E-32157237IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023193.1E-20158237IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.52E-13159238IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 390 aa     Download sequence    Send to blast
MAEKSDSGSR HHAYSRKQKS LGLLCSNFVS LYNKDDVETV CLDDAAMKLG VERRRIYDIV  60
NVMESIGVLT RKAKNRYLWI GLKGIPITLE QLKVLESNVL IAEYDEEDDK SFDHNDDYGE  120
GRFCTNDTAA KSKCGHAPRC CLLLSFTSSI ILAVAERKEK SLGQLTQNFV KLLLSSNAEM  180
VSLDEAAKLL LGDGQNPSYM RTKVRRLYDI ANVLSSLNLI EKTHQSDTRK PAFRWLGTKG  240
KCVDGVTVAI PPFAQKSGKR MFGTELTNVD FKRTKLLSSV ENKPIKTQVL SHDLKECNKA  300
VERQLQGSKS FVFGPFNPPK TAKEEITDKK EDNISDFESF ASSFRPSYHS QALHELFSHY  360
MEAYNSWFAE ITGGNNTQQP LKKSVHIGHS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-42152293228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020590776.10.0E2F transcription factor-like E2FE isoform X2
SwissprotQ8LSZ46e-97E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A2I0VT200.0A0A2I0VT20_9ASPA; E2F transcription factor-like E2FE
STRINGXP_008798029.11e-143(Phoenix dactylifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP31853884
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.23e-99DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]