PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PK01613.1
Organism
Cannabis sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis
Family HD-ZIP
Protein Properties Length: 838aa    MW: 91888.1 Da    PI: 5.887
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PK01613.1genomeCCBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox58.98.1e-191977357
               --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
   Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
               k  ++t+eq+e+Le+l++ +++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  PK01613.1 19 KYVRYTPEQVEALERLYHDCPKPSSMRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 77
               5679*****************************************************97 PP
2START181.54.8e-571633712205
                HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEEEEXXT CS
      START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlmvaelq 99 
                +a e+++e+++ka+ ++  Wv+++ +++g++++ +++ s+++sg a+ra+g+v  +++  v+e+l+d++ W ++++++++++v+s+g  g+++l +++l+
  PK01613.1 163 IADETLAEFLSKATGTAVEWVQMPGMKPGPDSIGIVAISHGCSGVAARACGLVGLEPT-RVAEILKDRPSWFRDCRAVDVINVLSTGngGTIELLYMQLY 261
                688999****************************************************.8888888888******************************* PP

                TXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHHHHHHHHHHHH CS
      START 100 alsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslvksglaegakt 195
                a+++l+p Rdf+ +Ry+  l++g++v++++S++++q+ p+    +++vRae+lpSg+li+p+++g+s +++v+h+dl+ ++++++lr+l++s++  +++t
  PK01613.1 262 APTTLAPaRDFWLLRYTSVLEDGSLVVCERSLNNTQNGPSmpvVQNFVRAEMLPSGYLIRPCEGGGSIIHVVDHMDLEPWSVPEVLRPLYESSTLLAQNT 361
                ***************************************999999******************************************************* PP

                HHHHTXXXXX CS
      START 196 wvatlqrqce 205
                ++a+l+++++
  PK01613.1 362 TMAALRHLRQ 371
                *****99876 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.7261478IPR001356Homeobox domain
SMARTSM003895.2E-161682IPR001356Homeobox domain
SuperFamilySSF466898.13E-171882IPR009057Homeodomain-like
CDDcd000867.98E-171979No hitNo description
PfamPF000462.2E-162077IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.602.1E-182177IPR009057Homeodomain-like
CDDcd146861.14E-671110No hitNo description
PROSITE profilePS5084826.711153381IPR002913START domain
CDDcd088751.43E-80157372No hitNo description
SuperFamilySSF559613.02E-38162373No hitNo description
Gene3DG3DSA:3.30.530.202.9E-23162368IPR023393START-like domain
SMARTSM002341.6E-42162372IPR002913START domain
PfamPF018521.3E-54163371IPR002913START domain
PfamPF086703.9E-51697837IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010067Biological Processprocambium histogenesis
GO:0010072Biological Processprimary shoot apical meristem specification
GO:0010089Biological Processxylem development
GO:0045597Biological Processpositive regulation of cell differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 838 aa     Download sequence    Send to blast
MAVTSSCKDG TKIAMDNGKY VRYTPEQVEA LERLYHDCPK PSSMRRQQLI RECPILSNIE  60
PKQIKVWFQN RRCREKQRKE ASRLQAVNRK LTAMNKLLME ENDRLQKQVS QLVYENSYFR  120
QQTQNATLAT TDTSCESVVT SGQHHLTPQH PPRDASPAGL LSIADETLAE FLSKATGTAV  180
EWVQMPGMKP GPDSIGIVAI SHGCSGVAAR ACGLVGLEPT RVAEILKDRP SWFRDCRAVD  240
VINVLSTGNG GTIELLYMQL YAPTTLAPAR DFWLLRYTSV LEDGSLVVCE RSLNNTQNGP  300
SMPVVQNFVR AEMLPSGYLI RPCEGGGSII HVVDHMDLEP WSVPEVLRPL YESSTLLAQN  360
TTMAALRHLR QISQEVSQPN ATGWGRRPAA LRALSQKLCK GFNEAVNGFT DEGWSMLESD  420
GIDDVTLLVN SSPSKIMGAN ISYANGFPSA SNSVLCAKAS MLLQNVPPAV LLRFLREHRS  480
EWADSSIDAY SAAAIKAGPC SLPGTRAGSF GGQVILPLAH TIEHEEFMEV IKLENMGHYR  540
DDMIMPVDIF LLQLCSGVDE NAVGNCAELV FAPIDASFSD DAPILPSGFR IISLDSGTDS  600
PSPNRTLDLA SALEVGPAAN RASGDNAGNS GSRKSVMTIA FQFAFEMHLQ ESVAAMARQY  660
VRSIIASVQR VALALSPSGL STHTGLRPPP GTPEALTLST WISQSYRCYL GVELLKNEGS  720
ESILKSLWQH LDAILCCSLK AMPVFTFANQ AGLDMLETTL LALQDITLEK IFDDNGRKTL  780
CSEFPQIMQQ GFMCLQGGIC MSSMGRPVSY EQAVAWKVLD EKENAHCICF MFINWSFV
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of vascular development. May promote differentiation of precambial and cambial cells. {ECO:0000269|PubMed:11402194, ECO:0000269|PubMed:15598805}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by miR165. {ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:8575317}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010102406.20.0homeobox-leucine zipper protein ATHB-8
SwissprotQ391230.0ATHB8_ARATH; Homeobox-leucine zipper protein ATHB-8
TrEMBLA0A2P5BF580.0A0A2P5BF58_TREOI; Octamer-binding transcription factor
STRINGXP_010102406.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19463387
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G32880.10.0homeobox gene 8
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Hategan L,Godza B,Kozma-Bognar L,Bishop GJ,Szekeres M
    Differential expression of the brassinosteroid receptor-encoding BRI1 gene in Arabidopsis.
    Planta, 2014. 239(5): p. 989-1001
    [PMID:24488524]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Kakehi J, et al.
    Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana.
    PLoS ONE, 2015. 10(1): p. e0117309
    [PMID:25625317]
  5. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  6. Liu S, et al.
    Expression of wild-type PtrIAA14.1, a poplar Aux/IAA gene causes morphological changes in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 388
    [PMID:26082787]
  7. Yamaguchi YL, et al.
    Root-Knot and Cyst Nematodes Activate Procambium-Associated Genes in Arabidopsis Roots.
    Front Plant Sci, 2017. 8: p. 1195
    [PMID:28747918]
  8. Yamazaki K, et al.
    Suppression of DELLA signaling induces procambial cell formation in culture.
    Plant J., 2018. 94(1): p. 48-59
    [PMID:29383774]