PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PK02428.1

Organism

Cannabis sativa

Taxonomic ID

3483

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis

Family

HSF

Protein Properties

Length: 271aa MW: 30282.5 Da PI: 4.6627

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PK02428.1	genome	CCBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	117.9	6.1e-37	4	95	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 Fl+k+y++++d+ ++++isw+eng++fvv+++ +fa+++LpkyFkh+nf+SFvRQLn+YgF+kv ++ weF++++F++g+kell++i+ PK02428.1 4 FLTKMYQLVDDPITDDVISWNENGTAFVVWKTADFARDLLPKYFKHNNFSSFVRQLNTYGFRKVVPDK---------WEFANENFRRGQKELLSEIR 91 9**************************************************************999.........****************** PP XXXX CS HSF_DNA-bind 99 rkks 102 r+k+ PK02428.1 92 RRKT 95 *986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00415	4.9E-59	1	93	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Gene3D	G3DSA:1.10.10.10	7.6E-38	2	93	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	8.84E-34	2	93	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	1.4E-32	4	93	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.6E-21	4	27	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.6E-21	42	54	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	43	67	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.6E-21	55	67	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009408	Biological Process	response to heat
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 271 aa Download sequence Send to blast
MAPFLTKMYQ LVDDPITDDV ISWNENGTAF VVWKTADFAR DLLPKYFKHN NFSSFVRQLN 60 TYGFRKVVPD KWEFANENFR RGQKELLSEI RRRKTLATTS TPAQVSPEGK STGEGSLSPS 120 NSGEDLGSTS SSSPDSKSPG SVETAAIAMT QFADLSGENE KLKKDNEVLS SELAQTKKQC 180 DELIAFLTEY MKVEPDQINR IMRQGIFRSM KGGKDCDDAE NEAEESSEEE EEENGENEDG 240 LKLFGVWVKA KENKKRNRNE GAGFTGGPPH P

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	1e-27	4	95	29	131	Heat shock factor protein 1
5d5v_B	1e-27	4	95	29	131	Heat shock factor protein 1
5d5v_D	1e-27	4	95	29	131	Heat shock factor protein 1
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Functional Description ? help Back to Top
Source	Description
UniProt	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024019588.1	1e-130	heat shock factor protein HSF24
Swissprot	P22335	1e-103	HSF24_SOLPE; Heat shock factor protein HSF24
TrEMBL	A0A2P5ATC8	1e-132	A0A2P5ATC8_PARAD; Heat shock transcription factor
STRING	EOX91407	1e-125	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF7114	32	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36990.1	6e-76	heat shock factor 4

Publications ? help Back to Top
Scharf KD, et al. Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA-binding domain of the yeast HSF. EMBO J., 1990. 9(13): p. 4495-501 [PMID:2148291]