PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PK03241.1
Organism
Cannabis sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis
Family bHLH
Protein Properties Length: 172aa    MW: 19782.4 Da    PI: 5.2078
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PK03241.1genomeCCBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH43.55.9e-144587855
               HHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
        HLH  8 rErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55
               +ErrRR+++N+++ +Lr+l+Pk +      Kl+ a+iL  A+eY+k+Lq
  PK03241.1 45 AERRRRKKLNERLYTLRSLVPKiS------KLDRASILGDAIEYVKDLQ 87
               7*********************66......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088815.6433786IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474593.93E-1841100IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.6E-154392IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.6E-114587IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.108.2E-1845100IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000837.15E-114589No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009555Biological Processpollen development
GO:0048657Biological Processanther wall tapetum cell differentiation
GO:0005634Cellular Componentnucleus
GO:0000978Molecular FunctionRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 172 aa     Download sequence    Send to blast
EKDSNKQEEG RSNSVSDCSD QIDDEDNGKY RRKSGKSDQC KNLFAERRRR KKLNERLYTL  60
RSLVPKISKL DRASILGDAI EYVKDLQSQA KELQDELEEQ SDNDGLNSNI NGKRNNVLSE  120
TLSRDDTNFR SRPEHEKVQN EFHLETSRSG SISKQNQDSD TTNDKAPQME VT
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A2e-143590257Transcription factor MYC2
5gnj_B2e-143590257Transcription factor MYC2
5gnj_E2e-143590257Transcription factor MYC2
5gnj_F2e-143590257Transcription factor MYC2
5gnj_G2e-143590257Transcription factor MYC2
5gnj_I2e-143590257Transcription factor MYC2
5gnj_M2e-143590257Transcription factor MYC2
5gnj_N2e-143590257Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
13051RRKSGKSDQCKNLFAERRRRKK
24552ERRRRKKL
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Plays a crucial role in tapetum development. Required for male fertility and pollen differentiation, especially during the post-meiotic transcriptional regulation of microspore development within the developing anther (PubMed:12535353). Binds E-box regions in the AHL16/TEK promoter. {ECO:0000269|PubMed:12535353, ECO:0000269|PubMed:24804694}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024028790.11e-79LOW QUALITY PROTEIN: transcription factor ABORTED MICROSPORES
SwissprotQ9ZVX22e-36AMS_ARATH; Transcription factor ABORTED MICROSPORES
TrEMBLA0A2P5EWP85e-92A0A2P5EWP8_TREOI; Basic helix-loop-helix transcription factor
STRINGXP_010107648.11e-78(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF42253247
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G16910.11e-28bHLH family protein
Publications ? help Back to Top
  1. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  2. Jiang J,Zhang Z,Cao J
    Pollen wall development: the associated enzymes and metabolic pathways.
    Plant Biol (Stuttg), 2013. 15(2): p. 249-63
    [PMID:23252839]
  3. Xu J, et al.
    ABORTED MICROSPORES Acts as a Master Regulator of Pollen Wall Formation in Arabidopsis.
    Plant Cell, 2014. 26(4): p. 1544-1556
    [PMID:24781116]
  4. Qian H, et al.
    Trace concentrations of imazethapyr (IM) affect floral organs development and reproduction in Arabidopsis thaliana: IM-induced inhibition of key genes regulating anther and pollen biosynthesis.
    Ecotoxicology, 2015. 24(1): p. 163-71
    [PMID:25348600]
  5. Xiong SX, et al.
    The transcription factors MS188 and AMS form a complex to activate the expression of CYP703A2 for sporopollenin biosynthesis in Arabidopsis thaliana.
    Plant J., 2016. 88(6): p. 936-946
    [PMID:27460657]
  6. Ferguson AC, et al.
    Biphasic regulation of the transcription factor ABORTED MICROSPORES (AMS) is essential for tapetum and pollen development in Arabidopsis.
    New Phytol., 2017. 213(2): p. 778-790
    [PMID:27787905]
  7. Lou Y, et al.
    Positive regulation of AMS by TDF1 and the formation of a TDF1-AMS complex are required for anther development in Arabidopsis thaliana.
    New Phytol., 2018. 217(1): p. 378-391
    [PMID:28940573]
  8. Bi H,Fan W,Zhang P
    C4 Protein of Sweet Potato Leaf Curl Virus Regulates Brassinosteroid Signaling Pathway through Interaction with AtBIN2 and Affects Male Fertility in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1689
    [PMID:29021807]