PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PK08903.1

Organism

Cannabis sativa

Taxonomic ID

3483

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis

Family

FAR1

Protein Properties

Length: 847aa MW: 97396.8 Da PI: 7.1726

Description

FAR1 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PK08903.1	genome	CCBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	FAR1	85	1.2e-26	89	191	1	91
FAR1 1 kfYneYAkevGFsvrkskskkskrngeitkrtfvCskegkreeekkk.........tekerr.......traetrtgCkaklkvkkekdgkwevtklele 84 +fY+eYA+++GF++ +++s++sk+++e+++++f Cs++g+++e +k+ + + +r+ ++t+Cka+++vk+++dgkw+++++++e PK08903.1 89 SFYQEYARSMGFNTAIQNSRRSKTSREFIDAKFACSRYGTKREYDKSfnrprsrqsK----QdpdnvtgRRSCSKTDCKASMHVKRRSDGKWVIHNFVKE 184 5*****************************************9999999876541....234455569999*********************** PP FAR1 85 HnHelap 91 HnHel p PK08903.1 185 HNHELLP 191 **975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF03101	2.1E-24	89	191	IPR004330	FAR1 DNA binding domain
Pfam	PF10551	1.2E-28	289	381	IPR018289	MULE transposase domain
PROSITE profile	PS50966	9.619	569	605	IPR007527	Zinc finger, SWIM-type
Pfam	PF04434	9.2E-6	577	604	IPR007527	Zinc finger, SWIM-type
SMART	SM00575	1.1E-8	580	607	IPR006564	Zinc finger, PMZ-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009585	Biological Process	red, far-red light phototransduction
GO:0010218	Biological Process	response to far red light
GO:0042753	Biological Process	positive regulation of circadian rhythm
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 847 aa Download sequence Send to blast
MDIDLRLPSG EHDKEGEEST AIDNMLDGEE KLHNGDIISG NMVDIGDEVH TEDGGDLNSP 60 TANMVVFKED TNLEPLSGME FESHGEAYSF YQEYARSMGF NTAIQNSRRS KTSREFIDAK 120 FACSRYGTKR EYDKSFNRPR SRQSKQDPDN VTGRRSCSKT DCKASMHVKR RSDGKWVIHN 180 FVKEHNHELL PAQAVSEQTR KMYAAMARQF AEYKSVVGLK NDPKNPFEKG RNLAVEAGDL 240 KILLDFFTQM QNVNANFFYA VDVGEDQRIK NLFWVDAKSR HDYANFSDVV SFDTTYIRNK 300 YKMPLALFIG VNQHYQFMLL GCALISDESV TTYSWLMQTW LKAMGGQVPK VIITDHDKVL 360 KSVISEVFPI VHHCFFLWHI LGRVSETLGH VIKQHENFMA KFEKCIYRSW TIEKFDKRWW 420 KILDKFELRG DEWIHSLYED RKQWVPSFMR DALLAGMSTV QRSDSVNYYF DKYVHKKTSV 480 QEFLKQHETI LQDRYEEEAK ADSDTWNKQP TLKSPSPLEK SVSGVYTHAV FKKFQVEVLG 540 AVACIPKKER QDEISIIFQV QDFEKGQDYQ VSWSEMKSEV SCLCRLFEYK GYLCRHALIV 600 LQMCGLSVIP PQYILKRWTR DAKNRHLTGE ESGQLQTRVQ RYNDLCQRAM KLCEEGSLSQ 660 ESYSIACRAL EETFGNCTSV NNSSRSLVDA GTSATHGILC MEEDSQSKNI VKTNKKKNPT 720 KKRKVSFEPD VITVGTQDSL QQMDNKLNPR AVTLDSYYGA QQNVQGMVQL NLMAPRDNYY 780 GNQQTIQGLG QLNSIAPSHD GYYSAQQSMH ALGQMEFFSR PSFTYGIRQD DPNVRTTSLH 840 DDASRHG

Sequence ? help Back to Top

Protein Sequence Length: 847 aa Download sequence Send to blast

MDIDLRLPSG EHDKEGEEST AIDNMLDGEE KLHNGDIISG NMVDIGDEVH TEDGGDLNSP  60
TANMVVFKED TNLEPLSGME FESHGEAYSF YQEYARSMGF NTAIQNSRRS KTSREFIDAK  120
FACSRYGTKR EYDKSFNRPR SRQSKQDPDN VTGRRSCSKT DCKASMHVKR RSDGKWVIHN  180
FVKEHNHELL PAQAVSEQTR KMYAAMARQF AEYKSVVGLK NDPKNPFEKG RNLAVEAGDL  240
KILLDFFTQM QNVNANFFYA VDVGEDQRIK NLFWVDAKSR HDYANFSDVV SFDTTYIRNK  300
YKMPLALFIG VNQHYQFMLL GCALISDESV TTYSWLMQTW LKAMGGQVPK VIITDHDKVL  360
KSVISEVFPI VHHCFFLWHI LGRVSETLGH VIKQHENFMA KFEKCIYRSW TIEKFDKRWW  420
KILDKFELRG DEWIHSLYED RKQWVPSFMR DALLAGMSTV QRSDSVNYYF DKYVHKKTSV  480
QEFLKQHETI LQDRYEEEAK ADSDTWNKQP TLKSPSPLEK SVSGVYTHAV FKKFQVEVLG  540
AVACIPKKER QDEISIIFQV QDFEKGQDYQ VSWSEMKSEV SCLCRLFEYK GYLCRHALIV  600
LQMCGLSVIP PQYILKRWTR DAKNRHLTGE ESGQLQTRVQ RYNDLCQRAM KLCEEGSLSQ  660
ESYSIACRAL EETFGNCTSV NNSSRSLVDA GTSATHGILC MEEDSQSKNI VKTNKKKNPT  720
KKRKVSFEPD VITVGTQDSL QQMDNKLNPR AVTLDSYYGA QQNVQGMVQL NLMAPRDNYY  780
GNQQTIQGLG QLNSIAPSHD GYYSAQQSMH ALGQMEFFSR PSFTYGIRQD DPNVRTTSLH  840
DDASRHG

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that recognizes and binds to the DNA consensus sequence 5'-CACGCGC-3'. Activates the expression of FHY1 and FHL involved in light responses. When associated with PHYA, protects it from being recognized and degraded by the COP1/SPA complex. Positive regulator of chlorophyll biosynthesis via the activation of HEMB1 gene expression. {ECO:0000269\|PubMed:11889039, ECO:0000269\|PubMed:12753585, ECO:0000269\|PubMed:17012604, ECO:0000269\|PubMed:18033885, ECO:0000269\|PubMed:18715961, ECO:0000269\|PubMed:22634759}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00078	ChIP-seq	Transfer from AT3G22170	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated after exposure to far-red light. Subject to a negative feedback regulation by PHYA signaling. Up-regulated by white light. {ECO:0000269\|PubMed:11889039, ECO:0000269\|PubMed:18033885, ECO:0000269\|PubMed:22634759}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024019194.1	0.0	protein FAR-RED ELONGATED HYPOCOTYL 3 isoform X1
Swissprot	Q9LIE5	0.0	FHY3_ARATH; Protein FAR-RED ELONGATED HYPOCOTYL 3
TrEMBL	A0A251Q297	0.0	A0A251Q297_PRUPE; Uncharacterized protein
STRING	XP_008229656.1	0.0	(Prunus mume)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF40	30	530

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G22170.2	0.0	far-red elongated hypocotyls 3

Publications ? help Back to Top
Chang N,Gao Y,Zhao L,Liu X,Gao H Arabidopsis FHY3/CPD45 regulates far-red light signaling and chloroplast division in parallel. Sci Rep, 2015. 5: p. 9612 [PMID:25872642] Wang C, et al. SCAB3 Is Required for Reorganization of Actin Filaments during Light Quality Changes. J Genet Genomics, 2015. 42(4): p. 161-8 [PMID:25953354] Wang W, et al. A pair of light signaling factors FHY3 and FAR1 regulates plant immunity by modulating chlorophyll biosynthesis. J Integr Plant Biol, 2016. 58(1): p. 91-103 [PMID:25989254] Ma L, et al. Arabidopsis FHY3 and FAR1 Regulate Light-Induced myo-Inositol Biosynthesis and Oxidative Stress Responses by Transcriptional Activation of MIPS1. Mol Plant, 2016. 9(4): p. 541-57 [PMID:26714049] Siddiqui H,Khan S,Rhodes BM,Devlin PF FHY3 and FAR1 Act Downstream of Light Stable Phytochromes. Front Plant Sci, 2016. 7: p. 175 [PMID:26941752] Li D, et al. FAR-RED ELONGATED HYPOCOTYL3 activates SEPALLATA2 but inhibits CLAVATA3 to regulate meristem determinacy and maintenance in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9375-80 [PMID:27469166] Liu L,Li B,Liu X FAR-RED ELONGATED HYPOCOTYL3 promotes floral meristem determinacy in Arabidopsis. Plant Signal Behav, 2016. 11(10): p. e1238545 [PMID:27660915] Ma L,Xue N,Fu X,Zhang H,Li G Arabidopsis thaliana FAR-RED ELONGATED HYPOCOTYLS3 (FHY3) and FAR-RED-IMPAIRED RESPONSE1 (FAR1) modulate starch synthesis in response to light and sugar. New Phytol., 2017. 213(4): p. 1682-1696 [PMID:27859295] Liu Y, et al. Light and Ethylene Coordinately Regulate the Phosphate Starvation Response through Transcriptional Regulation of PHOSPHATE STARVATION RESPONSE1. Plant Cell, 2017. 29(9): p. 2269-2284 [PMID:28842534] Joly-Lopez Z, et al. Abiotic Stress Phenotypes Are Associated with Conserved Genes Derived from Transposable Elements. Front Plant Sci, 2017. 8: p. 2027 [PMID:29250089]