PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PK11483.1

Organism

Cannabis sativa

Taxonomic ID

3483

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis

Family

GRAS

Protein Properties

Length: 524aa MW: 57900.4 Da PI: 5.2924

Description

GRAS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PK11483.1	genome	CCBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	GRAS	414.8	7.6e-127	162	523	1	373
GRAS 1 lvelLlecAeavssgdlelaqalLarlsel..aspdgdpmqRlaayfteALaarlarsvselykalppsetseknsseelaalklfsevsPilkfshlta 98 lv+ Ll+cAe v+ gdl a++l+++++ l + + + ++a yf AL++r+++ ++ + + ++e + ++e++P+lkf+h+ta PK11483.1 162 LVHMLLTCAESVQRGDLPFARSLIETMQPLlkRVNINCGIGKVAGYFIDALSRRIFSPRGSI----GAGPF-----EDE-VLYYHYYEACPYLKFAHFTA 251 689***********************99644444579*************922222....22222.....233.345579********** PP GRAS 99 NqaIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgspesgskeeleetgerLakfAeelgvpfefnvlvakrledleleeLrvkp 198 NqaIlea++g+++vH+iDf++++GlQWpaL+qaLa Rp+gpp lR+Tg+g+p+++ +++l+e+g rLa++A++++v+f f+ ++a+rled+++++L+v++ PK11483.1 252 NQAILEAFNGHDCVHVIDFNLMHGLQWPALIQALALRPGGPPLLRLTGIGPPSPDGRDSLREIGLRLADLAKSVNVRFAFRGVAAERLEDVKPWMLQVSS 351 ************************************************************************************************ PP GRAS 199 gEalaVnlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadhnsesFlerflealeyysalfdsleaklpreseerikvErellgreivnvv 298 +Ea+aVn+++qlhrll +++s +s +d vL+ +++l+Pk+++vveqeadhn+ Fl+rf+eal+yys++fdslea + ++ + +++l+rei+nvv PK11483.1 352 KEAVAVNSIMQLHRLLGSDHSWNSGIDMVLEWIRNLNPKIMTVVEQEADHNQVGFLDRFTEALYYYSTMFDSLEAC---SLQPDKALAEMYLQREICNVV 448 *********************************************************************998...348888889999***** PP GRAS 299 acegaerrerhetlekWrerleeaGFkpvplsekaakqaklllrkvksdgyrveeesgslvlgWkdrpLvsvSaW 373 +ceg++r+erhe l+kW +rl +aGF+p++l+++a kqa++ll ++ +gy vee++g+l+lgW++rpL+++SaW PK11483.1 449 CCEGSARVERHEPLAKWTNRLVQAGFQPLHLGSNAFKQASMLLTLFSAEGYCVEEKEGCLTLGWHSRPLIAASAW 523 ************************************************************************* PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM01129	1.0E-23	33	106	No hit	No description
Pfam	PF12041	4.3E-34	33	99	IPR021914	Transcriptional factor DELLA, N-terminal
PROSITE profile	PS50985	61.853	136	504	IPR005202	Transcription factor GRAS
Pfam	PF03514	2.6E-124	162	523	IPR005202	Transcription factor GRAS

Sequence ? help Back to Top
Protein Sequence Length: 524 aa Download sequence Send to blast
MGPYDSANSA GSSSSSGSSS SSSTSFKKPN DIDGFLAGAG YKVRSSDLQH VAQRLEQLET 60 VMVNSPASQI NHIASDTVHY NPSDISSWVD SLLSELNNPF PLSADLPDFP DLVINNPTER 120 NDVWAAEHGV PQPQQNIPPT PQLNQQPLTV VTAMEEDSGI RLVHMLLTCA ESVQRGDLPF 180 ARSLIETMQP LLKRVNINCG IGKVAGYFID ALSRRIFSPR GSIGAGPFED EVLYYHYYEA 240 CPYLKFAHFT ANQAILEAFN GHDCVHVIDF NLMHGLQWPA LIQALALRPG GPPLLRLTGI 300 GPPSPDGRDS LREIGLRLAD LAKSVNVRFA FRGVAAERLE DVKPWMLQVS SKEAVAVNSI 360 MQLHRLLGSD HSWNSGIDMV LEWIRNLNPK IMTVVEQEAD HNQVGFLDRF TEALYYYSTM 420 FDSLEACSLQ PDKALAEMYL QREICNVVCC EGSARVERHE PLAKWTNRLV QAGFQPLHLG 480 SNAFKQASML LTLFSAEGYC VEEKEGCLTL GWHSRPLIAA SAWX

Sequence ? help Back to Top

Protein Sequence Length: 524 aa Download sequence Send to blast

MGPYDSANSA GSSSSSGSSS SSSTSFKKPN DIDGFLAGAG YKVRSSDLQH VAQRLEQLET  60
VMVNSPASQI NHIASDTVHY NPSDISSWVD SLLSELNNPF PLSADLPDFP DLVINNPTER  120
NDVWAAEHGV PQPQQNIPPT PQLNQQPLTV VTAMEEDSGI RLVHMLLTCA ESVQRGDLPF  180
ARSLIETMQP LLKRVNINCG IGKVAGYFID ALSRRIFSPR GSIGAGPFED EVLYYHYYEA  240
CPYLKFAHFT ANQAILEAFN GHDCVHVIDF NLMHGLQWPA LIQALALRPG GPPLLRLTGI  300
GPPSPDGRDS LREIGLRLAD LAKSVNVRFA FRGVAAERLE DVKPWMLQVS SKEAVAVNSI  360
MQLHRLLGSD HSWNSGIDMV LEWIRNLNPK IMTVVEQEAD HNQVGFLDRF TEALYYYSTM  420
FDSLEACSLQ PDKALAEMYL QREICNVVCC EGSARVERHE PLAKWTNRLV QAGFQPLHLG  480
SNAFKQASML LTLFSAEGYC VEEKEGCLTL GWHSRPLIAA SAWX

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3g_A	2e-59	155	523	12	378	Protein SCARECROW
5b3h_A	2e-59	155	523	11	377	Protein SCARECROW
5b3h_D	2e-59	155	523	11	377	Protein SCARECROW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Transcription coactivator of the zinc finger transcription factors GAF1/IDD2 and ENY/IDD1 in regulation of gibberellin homeostasis and signaling (PubMed:25035403). No effect of the BOI proteins on its stability. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression. In contrast to RGA, it is less sensitive to GA. Its activity is probably regulated by other phytohormones such as auxin and ethylene. {ECO:0000269\|PubMed:11487693, ECO:0000269\|PubMed:11606551, ECO:0000269\|PubMed:11606552, ECO:0000269\|PubMed:14973286, ECO:0000269\|PubMed:15128937, ECO:0000269\|PubMed:16034591, ECO:0000269\|PubMed:17933900, ECO:0000269\|PubMed:25035403, ECO:0000269\|PubMed:9389651}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018841073.1	0.0	PREDICTED: DELLA protein SLN1-like
Swissprot	Q9LQT8	1e-163	GAI_ARATH; DELLA protein GAI
TrEMBL	A0A2P5BDH2	0.0	A0A2P5BDH2_TREOI; DELLA transcription factor
STRING	XP_009371410.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF803	34	121

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G14920.1	1e-145	GRAS family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Gallego-Giraldo C, et al. Role of the gibberellin receptors GID1 during fruit-set in Arabidopsis. Plant J., 2014. 79(6): p. 1020-1032 [PMID:24961590] Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Marín-de la Rosa N, et al. Genome Wide Binding Site Analysis Reveals Transcriptional Coactivation of Cytokinin-Responsive Genes by DELLA Proteins. PLoS Genet., 2015. 11(7): p. e1005337 [PMID:26134422] Shi H,Wei Y,Wang Q,Reiter RJ,He C Melatonin mediates the stabilization of DELLA proteins to repress the floral transition in Arabidopsis. J. Pineal Res., 2016. 60(3): p. 373-9 [PMID:26887824] Lee SA, et al. Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue. Mol Plant, 2016. 9(6): p. 870-84 [PMID:26970019] Qu J,Kang SG,Hah C,Jang JC Molecular and cellular characterization of GA-Stimulated Transcripts GASA4 and GASA6 in Arabidopsis thaliana. Plant Sci., 2016. 246: p. 1-10 [PMID:26993231] Shahnejat-Bushehri S,Nobmann B,Devi Allu A,Balazadeh S JUB1 suppresses Pseudomonas syringae-induced defense responses through accumulation of DELLA proteins. Plant Signal Behav, 2016. 11(6): p. e1181245 [PMID:27159137] Shahnejat-Bushehri S,Tarkowska D,Sakuraba Y,Balazadeh S Arabidopsis NAC transcription factor JUB1 regulates GA/BR metabolism and signalling. Nat Plants, 2016. 2: p. 16013 [PMID:27249348] Wang H, et al. The DELLA-CONSTANS Transcription Factor Cascade Integrates Gibberellic Acid and Photoperiod Signaling to Regulate Flowering. Plant Physiol., 2016. 172(1): p. 479-88 [PMID:27406167] Li W,Wang H,Yu D Arabidopsis WRKY Transcription Factors WRKY12 and WRKY13 Oppositely Regulate Flowering under Short-Day Conditions. Mol Plant, 2016. 9(11): p. 1492-1503 [PMID:27592586] Liu B,De Storme N,Geelen D Gibberellin Induces Diploid Pollen Formation by Interfering with Meiotic Cytokinesis. Plant Physiol., 2017. 173(1): p. 338-353 [PMID:27621423] Matsuoka K, et al. Differential Cellular Control by Cotyledon-Derived Phytohormones Involved in Graft Reunion of Arabidopsis Hypocotyls. Plant Cell Physiol., 2016. 57(12): p. 2620-2631 [PMID:27986917] Zentella R, et al. The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA. Nat. Chem. Biol., 2017. 13(5): p. 479-485 [PMID:28244988] Zhang Y, et al. GA-DELLA pathway is involved in regulation of nitrogen deficiency-induced anthocyanin accumulation. Plant Cell Rep., 2017. 36(4): p. 557-569 [PMID:28275852] Zhang L,Chen L,Yu D Transcription Factor WRKY75 Interacts with DELLA Proteins to Affect Flowering. Plant Physiol., 2018. 176(1): p. 790-803 [PMID:29133369] Nelson SK,Ariizumi T,Steber CM Biology in the Dry Seed: Transcriptome Changes Associated with Dry Seed Dormancy and Dormancy Loss in the Arabidopsis GA-Insensitive sleepy1-2 Mutant. Front Plant Sci, 2017. 8: p. 2158 [PMID:29312402] Liu B,De Storme N,Geelen D Cold-Induced Male Meiotic Restitution in Arabidopsis thaliana Is Not Mediated by GA-DELLA Signaling. Front Plant Sci, 2018. 9: p. 91 [PMID:29459879] Zhang Y, et al. DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6. Plant Cell Rep., 2018. 37(7): p. 981-992 [PMID:29574486] Felipo-Benavent A, et al. Regulation of xylem fiber differentiation by gibberellins through DELLA-KNAT1 interaction. Development, 2019. [PMID:30389856] Wright DA, et al. Recovery of YAC-end sequences through complementation of an Escherichia coli pyrF mutation. Nucleic Acids Res., 1997. 25(13): p. 2679-80 [PMID:9185581]