PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PK20163.1

Organism

Cannabis sativa

Taxonomic ID

3483

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis

Family

WRKY

Protein Properties

Length: 141aa MW: 16150.5 Da PI: 9.6053

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PK20163.1	genome	CCBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	98.3	4.8e-31	32	91	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dgy+WrKYGqK+ ++++ pr+Y++C++a +Cpvkkkv+rsaedp+++++tYegeH h+ PK20163.1 32 VKDGYQWRKYGQKVTRDNPSPRAYFKCSFApNCPVKKKVQRSAEDPSLLVVTYEGEHMHN 91 58*************************99**************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50811	25.293	27	93	IPR003657	WRKY domain
Gene3D	G3DSA:2.20.25.80	1.9E-29	27	91	IPR003657	WRKY domain
SuperFamily	SSF118290	7.19E-26	28	91	IPR003657	WRKY domain
SMART	SM00774	4.7E-35	32	92	IPR003657	WRKY domain
Pfam	PF03106	1.6E-25	33	90	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 141 aa Download sequence Send to blast
XEINYKSKVS TIYVRTDSSS DDHHDHNKTL VVKDGYQWRK YGQKVTRDNP SPRAYFKCSF 60 APNCPVKKKV QRSAEDPSLL VVTYEGEHMH NNSHNIKKSS MVRSLANNST ITLDHHDHGP 120 VLHQFLVNQM ASSLTKDSNF X

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	1e-21	26	91	6	72	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Positively modulates defense-related gene expression and disease resistance. {ECO:0000269\|PubMed:12068113}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid and pathogens. {ECO:0000269\|PubMed:11449049, ECO:0000269\|PubMed:12068113}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009137737.1	1e-50	PREDICTED: WRKY transcription factor 18
Refseq	XP_010101038.1	2e-49	probable WRKY transcription factor 40 isoform X1
Refseq	XP_024024355.1	1e-49	probable WRKY transcription factor 40 isoform X2
Swissprot	Q9C5T4	3e-47	WRK18_ARATH; WRKY transcription factor 18
TrEMBL	A0A2P5FN96	3e-56	A0A2P5FN96_TREOI; WRKY domain containing protein
STRING	Bra019123.1-P	2e-49	(Brassica rapa)
STRING	XP_010101038.1	6e-49	(Morus notabilis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF973	34	115

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G31800.2	2e-48	WRKY DNA-binding protein 18

Publications ? help Back to Top
Keates SE,Kostman TA,Anderson JD,Bailey BA Altered gene expression in three plant species in response to treatment with Nep1, a fungal protein that causes necrosis. Plant Physiol., 2003. 132(3): p. 1610-22 [PMID:12857840] Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Bülow L,Steffens NO,Galuschka C,Schindler M,Hehl R AthaMap: from in silico data to real transcription factor binding sites. In Silico Biol. (Gedrukt), 2006. 6(3): p. 243-52 [PMID:16922688] Deeken R, et al. Identification of Arabidopsis thaliana phloem RNAs provides a search criterion for phloem-based transcripts hidden in complex datasets of microarray experiments. Plant J., 2008. 55(5): p. 746-59 [PMID:18485061] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zhang Y, et al. Regulation of oncogene expression in T-DNA-transformed host plant cells. PLoS Pathog., 2015. 11(1): p. e1004620 [PMID:25615824] Geilen K,Böhmer M Dynamic subnuclear relocalisation of WRKY40 in response to Abscisic acid in Arabidopsis thaliana. Sci Rep, 2015. 5: p. 13369 [PMID:26293691] Geilen K,Böhmer M Dynamic subnuclear relocalization of WRKY40, a potential new mechanism of ABA-dependent transcription factor regulation. Plant Signal Behav, 2015. 10(11): p. e1106659 [PMID:26479147] Lu K, et al. Overexpression of an Arabidopsis cysteine-rich receptor-like protein kinase, CRK5, enhances abscisic acid sensitivity and confers drought tolerance. J. Exp. Bot., 2016. 67(17): p. 5009-27 [PMID:27406784] Birkenbihl RP,Kracher B,Roccaro M,Somssich IE Induced Genome-Wide Binding of Three Arabidopsis WRKY Transcription Factors during Early MAMP-Triggered Immunity. Plant Cell, 2017. 29(1): p. 20-38 [PMID:28011690]