PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PK23013.1

Organism

Cannabis sativa

Taxonomic ID

3483

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis

Family

bHLH

Protein Properties

Length: 237aa MW: 25988.4 Da PI: 9.0348

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PK23013.1	genome	CCBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	38.7	1.8e-12	79	126	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rE++RRdr+N++f eL ++l + + +K +Ka+iL Av+ +++L PK23013.1 79 TKACREKQRRDRLNDKFVELGSILEPG---RPPKTDKAAILIDAVRMVHQL 126 6789********************8...89*************9999 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	4.58E-14	66	141	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	13.224	75	126	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	5.56E-9	78	131	No hit	No description
Gene3D	G3DSA:4.10.280.10	1.0E-13	78	148	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	3.5E-10	79	126	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.7E-10	81	132	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 237 aa Download sequence Send to blast
MVSPENTNWL FDYGLIDDIP VPDGNFPVSS SGFNWPVQTL NGSSSVSVEI DGSLGDSEGL 60 KESGSKKRSR SESRNGSSTK ACREKQRRDR LNDKFVELGS ILEPGRPPKT DKAAILIDAV 120 RMVHQLRGEA QKLKDSNSSL QEKIKELKVE KNELRDEKQR LKVEKEKLEQ QLKGMNAQPG 180 FLAPPPAIPA AFAAAQGQAP GNKLVPFIGY PGVAMWQFMP PASVDTSQDH VLRPPVA

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008365724.1	1e-143	transcription factor ILR3
Refseq	XP_021811132.1	1e-142	transcription factor ILR3
Swissprot	Q9FH37	1e-121	ILR3_ARATH; Transcription factor ILR3
TrEMBL	A0A2P5C4F5	1e-150	A0A2P5C4F5_TREOI; Basic helix-loop-helix transcription factor
STRING	XP_008365724.1	1e-142	(Malus domestica)
STRING	EMJ12866	1e-141	(Prunus persica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1602	34	86

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	3e-78	bHLH family protein

Publications ? help Back to Top
Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]