PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PSME_00020748-RA

Organism

Pseudotsuga menziesii

Taxonomic ID

3357

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Pseudotsuga

Family

bHLH

Protein Properties

Length: 294aa MW: 32196.6 Da PI: 5.3678

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PSME_00020748-RA	genome	PRS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	35.4	1.9e-11	129	171	7	54
HHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS HLH 7 erErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 ++ErrRR+++N+ ++ Lr+++Pk + K + +iL AveY+k+L PSME_00020748-RA 129 MAERRRRKKVNDHLFMLRSVVPKvS------KEDRTSILGDAVEYLKEL 171 79*******************55......899999********98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	9.68E-14	120	183	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	13.853	122	171	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.6E-9	128	171	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.6E-9	128	177	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.93E-10	129	173	No hit	No description
Gene3D	G3DSA:4.10.280.10	1.8E-12	129	179	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 294 aa Download sequence Send to blast
MEMAWTGLLD ESFSSFRAIL NGGGEYDFYS TMDANEMALE ALLGSSLMCL DGSVLINVQT 60 ETIDAFHHMD YSITTIAEML EHPNQGSDEL GWGNASHASN NNNNNGYASA ASVGRGRGRK 120 TGFPAKNLMA ERRRRKKVND HLFMLRSVVP KVSKEDRTSI LGDAVEYLKE LLQCINGLHI 180 ELMSGSSNSK PLASTLLDFP CIMNREYHAS LLNPEVEPVR VEVNTREGKA LNIHMFCSKK 240 AGMLLSTIIA LDGVGLDVKQ AVISCFNGFA LEVLQAEQPN GNATAEEIKA LLLH

Functional Description ? help Back to Top
Source	Description
UniProt	Mediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (PubMed:18641265). Functions as a dimer with SPCH during stomatal initiation (PubMed:18641265, PubMed:28507175). {ECO:0000269\|PubMed:18641265, ECO:0000269\|PubMed:28507175}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021673395.1	1e-65	transcription factor ICE1-like isoform X1
Refseq	XP_022741193.1	1e-65	transcription factor ICE1-like isoform X2
Swissprot	Q9LPW3	2e-59	SCRM2_ARATH; Transcription factor SCREAM2
TrEMBL	D5A934	1e-85	D5A934_PICSI; Uncharacterized protein
STRING	cassava4.1_005158m	8e-65	(Manihot esculenta)
STRING	cassava4.1_005473m	6e-65	(Manihot esculenta)
STRING	GSMUA_Achr6P08070_001	5e-66	(Musa acuminata)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G12860.1	1e-54	bHLH family protein

Publications ? help Back to Top
Tarasov VA,Khadeeva NV,Mel'nik VA,Ezhova TA,Shestakov SV The Atlg12860 gene of Arabidopsis thaliana determines cathelicidin-like antimicrobial activity. Dokl. Biol. Sci., 2009. [PMID:19760875] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Emmerstorfer A, et al. Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris. Biotechnol J, 2015. 10(4): p. 623-35 [PMID:25641738] Lee HG,Seo PJ The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis. Plant J., 2015. 82(6): p. 962-77 [PMID:25912720] Raissig MT,Abrash E,Bettadapur A,Vogel JP,Bergmann DC Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(29): p. 8326-31 [PMID:27382177] Fu ZW,Wang YL,Lu YT,Yuan TT Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis. Plant Sci., 2016. 252: p. 282-289 [PMID:27717464] de Marcos A, et al. A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development. Plant Physiol., 2017. 174(2): p. 823-842 [PMID:28507175]