PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PSME_00022457-RA

Organism

Pseudotsuga menziesii

Taxonomic ID

3357

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Pseudotsuga

Family

bHLH

Protein Properties

Length: 322aa MW: 35300.2 Da PI: 6.8525

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PSME_00022457-RA	genome	PRS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	24.3	5.5e-08	157	199	7	54
HHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 7 erErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++Err R+++N++++ Lr+++Pk K + +iL veY+k+L PSME_00022457-RA 157 MAERRQRKKVNDRLFMLRSMVPKV-----SKTDRTSILGDDVEYLKEL 199 79*******************5.....4999999******9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	12.887	150	199	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	6.67E-11	153	211	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.5E-8	156	205	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.5E-6	156	199	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.2E-10	157	207	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.44E-7	157	203	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 322 aa Download sequence Send to blast
MEMAWTGLLD ESFSSFRAIL NGGGEYDFYS TMDANEMALE ALLGSSLMCP DGSVLSNVQT 60 KTIDAFHHME CSITTIAEML EHPNQGSDEL GLLQRRAEIE SRFHKNEGSH KLNGMVGGSQ 120 GNASHAANNN NNNGYASAAS VGRGRGRKIG FPAKNLMAER RQRKKVNDRL FMLRSMVPKV 180 SKTDRTSILG DDVEYLKELL QRINGLHIEL MSGSSNSKPL ASTLLDFPCI MNREYHASLL 240 NPKVEPVRVE VNTREGKALN IHMFCSKKVG MLLSTISALD GVGLDVKQAV ISCFNGFALE 300 VLQAEQPNGN ATVEEIKALL LH

Functional Description ? help Back to Top
Source	Description
UniProt	Mediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (PubMed:18641265). Functions as a dimer with SPCH during stomatal initiation (PubMed:18641265, PubMed:28507175). {ECO:0000269\|PubMed:18641265, ECO:0000269\|PubMed:28507175}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_022741193.1	6e-66	transcription factor ICE1-like isoform X2
Swissprot	Q9LPW3	1e-59	SCRM2_ARATH; Transcription factor SCREAM2
TrEMBL	D5A934	5e-84	D5A934_PICSI; Uncharacterized protein
STRING	cassava4.1_005473m	1e-64	(Manihot esculenta)
STRING	GSMUA_Achr6P08070_001	7e-66	(Musa acuminata)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G12860.1	2e-61	bHLH family protein

Publications ? help Back to Top
Tarasov VA,Khadeeva NV,Mel'nik VA,Ezhova TA,Shestakov SV The Atlg12860 gene of Arabidopsis thaliana determines cathelicidin-like antimicrobial activity. Dokl. Biol. Sci., 2009. [PMID:19760875] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Emmerstorfer A, et al. Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris. Biotechnol J, 2015. 10(4): p. 623-35 [PMID:25641738] Lee HG,Seo PJ The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis. Plant J., 2015. 82(6): p. 962-77 [PMID:25912720] Raissig MT,Abrash E,Bettadapur A,Vogel JP,Bergmann DC Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(29): p. 8326-31 [PMID:27382177] Fu ZW,Wang YL,Lu YT,Yuan TT Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis. Plant Sci., 2016. 252: p. 282-289 [PMID:27717464] de Marcos A, et al. A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development. Plant Physiol., 2017. 174(2): p. 823-842 [PMID:28507175]