PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pahal.C00478.3
Organism
Panicum hallii
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Panicinae; Panicum
Family E2F/DP
Protein Properties Length: 375aa    MW: 41001.1 Da    PI: 4.3364
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pahal.C00478.3genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP83.71.5e-2659124171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+llt+kfl+ll+ ++ giv+ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+irwkg
  Pahal.C00478.3  59 RYDSSLGLLTKKFLNLLKGAPGGIVDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNNIRWKG 124
                     6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.106.5E-2857125IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.6E-3559124IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.33E-1659122IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.3E-2361124IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.18E-49135241No hitNo description
SuperFamilySSF1440745.49E-34136241No hitNo description
PfamPF164211.9E-34140239IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 375 aa     Download sequence    Send to blast
MMSPGYANAG SSPVPTPPSG KGLKSSAKPK ATKGQKPCPQ TPLSFGSPGN PSTPVGGCRY  60
DSSLGLLTKK FLNLLKGAPG GIVDLNNAAE TLEVQKRRIY DITNVLEGIG LIEKKLKNNI  120
RWKGIDDSRP GEVSDDMSIL QADIEALTVQ EQNLDERINE MRDRLRELTE DENNQKWLYV  180
TEDDIKSLPC FQNQTLIAIK APHGTTLEVP DPDEVNDYPQ RRYRIVLRST MGPIDVYLVS  240
QFEEMSGMET PPRPTPTISM DSLENPRTPL AAECSKAAGT EPTIQQGFTL PPDAPSSSQD  300
IGGMMKIVPS ELDTDADYWL LSDTGVSITD MWKTAPDVEW DGIEKFNAED FLEVSTPRQQ  360
DKPADVVDGP SCMS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-2348125274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0343490.0BT034349.1 Zea mays full-length cDNA clone ZM_BFc0009D23 mRNA, complete cds.
GenBankBT0644350.0BT064435.1 Zea mays full-length cDNA clone ZM_BFc0168K16 mRNA, complete cds.
GenBankEU9655380.0EU965538.1 Zea mays clone 286746 transcription factor E2F2 mRNA, complete cds.
GenBankEU9739800.0EU973980.1 Zea mays clone 425487 transcription factor E2F2 mRNA, complete cds.
GenBankJX4699700.0JX469970.1 Zea mays subsp. mays clone UT3233 E2F-DP-type transcription factor mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_025804811.10.0transcription factor E2FA-like isoform X1
SwissprotQ9FNY01e-115E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A2S3H5X20.0A0A2S3H5X2_9POAL; Uncharacterized protein
TrEMBLA0A3L6R6R80.0A0A3L6R6R8_PANMI; Transcription factor E2FA-like isoform X1
STRINGPavir.J28624.1.p0.0(Panicum virgatum)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-108E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]