PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pahal.G00115.4

Organism

Panicum hallii

Taxonomic ID

206008

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Panicinae; Panicum

Family

E2F/DP

Protein Properties

Length: 374aa MW: 41814.4 Da PI: 5.6806

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pahal.G00115.4	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	82	5.1e-26	55	120	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL llt+kf++ll+++++gi++ln+ a++L dv ++RRiYDi+NVLe+++liekk kn+i wkg Pahal.G00115.4 55 RYDSSLALLTRKFVNLLKQAQDGILDLNSTADKL---DV--QKRRIYDITNVLEGIGLIEKKLKNRICWKG 120 6899****************************.....****************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.6E-27	53	122	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	1.33E-16	55	118	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	7.5E-33	55	120	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	8.2E-23	57	120	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	4.50E-33	130	236	No hit	No description
SuperFamily	SSF144074	2.62E-29	132	237	No hit	No description
Pfam	PF16421	1.9E-29	135	235	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 374 aa Download sequence Send to blast
MVRPQYLENL QGHTSQRLNA ANLYLRHLYQ MLLNACLSVA SASPGNPPTP AGPCRYDSSL 60 ALLTRKFVNL LKQAQDGILD LNSTADKLDV QKRRIYDITN VLEGIGLIEK KLKNRICWKG 120 LDESGTNLDN DLSVLKSEIE NLNLQEQALD EHISKMHKKL KELTEDESRQ RWLFLTEDDI 180 KGLPCFQNQT LIAIKAPHGS SVEVPNPDVM TGESFRRRYR IIIRSTMGPI ALYLVSNFEM 240 KSEEKLDETA TLASHTHLAK RASSVKGPRT KRAGQSCSKE VVVNAQQIHK TPDLNAPYPS 300 EGVLRKITPS DVDSDADYWL LTDDDVSITD MWRTAPEMQW DQIDPNDFLA EEVSTPGPGT 360 LSQQPAAIGE TYS*

Sequence ? help Back to Top

Protein Sequence Length: 374 aa Download sequence Send to blast

MVRPQYLENL QGHTSQRLNA ANLYLRHLYQ MLLNACLSVA SASPGNPPTP AGPCRYDSSL  60
ALLTRKFVNL LKQAQDGILD LNSTADKLDV QKRRIYDITN VLEGIGLIEK KLKNRICWKG  120
LDESGTNLDN DLSVLKSEIE NLNLQEQALD EHISKMHKKL KELTEDESRQ RWLFLTEDDI  180
KGLPCFQNQT LIAIKAPHGS SVEVPNPDVM TGESFRRRYR IIIRSTMGPI ALYLVSNFEM  240
KSEEKLDETA TLASHTHLAK RASSVKGPRT KRAGQSCSKE VVVNAQQIHK TPDLNAPYPS  300
EGVLRKITPS DVDSDADYWL LTDDDVSITD MWRTAPEMQW DQIDPNDFLA EEVSTPGPGT  360
LSQQPAAIGE TYS*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	8e-25	50	121	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_025824204.1	0.0	transcription factor E2FA-like isoform X4
Swissprot	Q9FNY0	1e-101	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A2S3I797	0.0	A0A2S3I797_9POAL; Uncharacterized protein
STRING	Pavir.J29330.1.p	0.0	(Panicum virgatum)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	5e-97	E2F transcription factor 3

Link Out ? help Back to Top
Phytozome	Pahal.G00115.4

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]