PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pahal.H01961.1

Organism

Panicum hallii

Taxonomic ID

206008

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Panicinae; Panicum

Family

WRKY

Protein Properties

Length: 1623aa MW: 179950 Da PI: 6.5596

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pahal.H01961.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	83.1	2.8e-26	1322	1379	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 +Dgy+W KYG K+ kgse+ rsYY+C ++gC vkkkvers d+++vei+Y++ Hnh Pahal.H01961.1 1322 SDGYSWLKYGLKQAKGSENQRSYYKCIFQGCLVKKKVERSLPDGQIVEIVYKNAHNHA 1379 7********************************************************7 PP
2	WRKY	88.6	5.2e-28	1488	1547	1	59
---SS-EEEEEEE--T.T-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevk.gsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 +dDg++WrKYG+K+ + g+++prsYYrC++agCp++k+ver ++d++vv++tY+g+Hnh+ Pahal.H01961.1 1488 MDDGFRWRKYGKKSLRlGNPNPRSYYRCAMAGCPMRKHVERMSHDQRVVVTTYKGKHNHD 1547 59**********9779***************************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd14798	4.09E-15	9	120	No hit	No description
SuperFamily	SSF52540	1.04E-49	149	414	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Gene3D	G3DSA:3.40.50.300	5.4E-5	152	186	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Pfam	PF00931	4.1E-50	161	440	IPR002182	NB-ARC
PRINTS	PR00364	4.0E-12	177	192	No hit	No description
Gene3D	G3DSA:3.40.50.300	6.7E-11	187	304	IPR027417	P-loop containing nucleoside triphosphate hydrolase
PRINTS	PR00364	4.0E-12	250	264	No hit	No description
PRINTS	PR00364	4.0E-12	347	361	No hit	No description
SuperFamily	SSF52058	5.1E-26	510	861	IPR032675	Leucine-rich repeat domain, L domain-like
Gene3D	G3DSA:3.80.10.10	2.3E-19	547	844	IPR032675	Leucine-rich repeat domain, L domain-like
PRINTS	PR00364	4.0E-12	648	664	No hit	No description
Gene3D	G3DSA:3.30.200.20	1.7E-19	953	1028	No hit	No description
SuperFamily	SSF56112	8.26E-79	959	1251	IPR011009	Protein kinase-like domain
PROSITE profile	PS50011	46.803	961	1218	IPR000719	Protein kinase domain
Pfam	PF00069	1.1E-66	962	1217	IPR000719	Protein kinase domain
Gene3D	G3DSA:1.10.510.10	9.1E-59	1029	1224	No hit	No description
PROSITE profile	PS50811	22.837	1316	1381	IPR003657	WRKY domain
Gene3D	G3DSA:2.20.25.80	3.8E-24	1318	1381	IPR003657	WRKY domain
SuperFamily	SSF118290	3.4E-21	1320	1381	IPR003657	WRKY domain
SMART	SM00774	7.4E-30	1321	1380	IPR003657	WRKY domain
Pfam	PF03106	6.4E-20	1323	1378	IPR003657	WRKY domain
Gene3D	G3DSA:2.20.25.80	6.4E-31	1473	1549	IPR003657	WRKY domain
SuperFamily	SSF118290	6.67E-24	1480	1549	IPR003657	WRKY domain
PROSITE profile	PS50811	31.445	1483	1549	IPR003657	WRKY domain
SMART	SM00774	5.8E-31	1488	1548	IPR003657	WRKY domain
Pfam	PF03106	1.9E-21	1489	1547	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0006468	Biological Process	protein phosphorylation
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0004672	Molecular Function	protein kinase activity
GO:0005524	Molecular Function	ATP binding
GO:0043531	Molecular Function	ADP binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 1623 aa Download sequence Send to blast
MEVQMSSSSL GAMGSLLGKL CSLLVSPEDQ LPEPLQLQKD KLELLKQDLE EINKFLVNLS 60 WMEDPNMMVK HWMNEVRDLS YDIEDYIDKT MHSDPNTNEA SSSWVDELSS FVKKAKDAHE 120 RHNRYDLGRW ASDPRFVVDG QGWIPRLNGE ATELVGIGDS KAQLIKQLNI DVERRLVVSI 180 HGPVGVGKTT LAKEVYCQIG GQFQCRAFVR ASKMPDTRRL LRSMIFQVQR HQRPPQGLTV 240 QDLIDHLRKL LQQKRYLIVI DGLWETTSWD IVSSAFPEDT HCSRVLVTTD IQEVALECCD 300 YQSDGIFTME PLSTNDTREL LFNRAFGSNH ECSEQLKEVS EEVIKKCCGF PLATLCIAQV 360 LASDPDNSEL WHHIKESLSC DIRNNLTSED MLRGIIGLSY NSLPHHLKTC LLYFHMYPEG 420 YMFLKTDLVK QWAAEGFIGA VAGKNTSEIA ESYFDELVCR GFIQPNCINF SDGVMFYTVH 480 YTIFEVIRCK SMEGNFNTVI DYSEISTKLS AKVRRLSIRF SNAKYATKPE GITLSPVRSL 540 IFYGLVECLP SITEFESLRV LHLEFWGAHG DVLDLSGIDR LFQLRYLWVS TNVTVKLPTM 600 MTALQYLETL EIYAKVTTVP TDIVNLATLQ HLCLYGDINL PDGIAQMRSL RTLKSFDLSG 660 NSEDNVRSLG ELKNLHQLHL TCSVAPSDRL KRNLIALVSS LGKLGNLNSL VLAPGGSCTS 720 IYSDCSNSVS SVPVSLQILE LLPPICIFSR LPEWFGQLHN LRILKVVVTD LLRDDIDVII 780 GLQELTNLSL YVRKRTRESI IFKSATFPVL KYFKFRCGVL QLAFQAKAMP NLQKLKLEFN 840 AHRGDQYGGM LSGIEHLLNL REVAARILAG AGVKESDRMA AESAFIDTIS KKSGLPMINM 900 QWVDSFDEDL RRHHYPFSPH CSGTLGQCPA SPTSWQDESR SSSSHQPLPL IPGSSSHYRQ 960 WEKGMLLGSG TLGQVYEGFN SENGQICVIK EIKVSTDDSN SKECLRQLNQ EIVLLSQLSH 1020 PNIVQYYGSV LSNETLSVYL EYVSGISIHK MLQLGGPLGE ALLRNYTAQI LSGLAYLHGH 1080 NTVHSNIKVA NILVDFNGDT IKLADFGMAK LISQYTSMKS FKGSPSSMAP EVISNSNGYK 1140 FSVDLWSLGC TILEMATGKP PWGQYEGAAS IFKICNSQDI PDIPDHLSSE AKSFLKLCLQ 1200 RDPAARPTAA QLMDHPFAKD HPTSTDGNNI RISQFSDVPA STSHLDGIAI DPGKTLDVLR 1260 EASPDSNRNP TATVDITDLE ADFSLRMAGE GEDEATGTTT TFHVPTAAVG EELSAAFQPI 1320 PSDGYSWLKY GLKQAKGSEN QRSYYKCIFQ GCLVKKKVER SLPDGQIVEI VYKNAHNHAK 1380 PHVWARNSSA PAQLLQDGGG GDASDHTFGG MSGVTVATLE NPTVSVGNDD VVRVRSPRST 1440 GCSGLDEHEK DPKRMRKDID GEGISMAGSR TVREPRVVVQ TTSDVDFMDD GFRWRKYGKK 1500 SLRLGNPNPR SYYRCAMAGC PMRKHVERMS HDQRVVVTTY KGKHNHDAPA RGPSSLDRPP 1560 PAVANQSSGG AVQQQYARGF SGQGSVGVSS ASAQGADAGS SFEVSTLKDY VTGDAAFISE 1620 LR*

Sequence ? help Back to Top

Protein Sequence Length: 1623 aa Download sequence Send to blast

MEVQMSSSSL GAMGSLLGKL CSLLVSPEDQ LPEPLQLQKD KLELLKQDLE EINKFLVNLS  60
WMEDPNMMVK HWMNEVRDLS YDIEDYIDKT MHSDPNTNEA SSSWVDELSS FVKKAKDAHE  120
RHNRYDLGRW ASDPRFVVDG QGWIPRLNGE ATELVGIGDS KAQLIKQLNI DVERRLVVSI  180
HGPVGVGKTT LAKEVYCQIG GQFQCRAFVR ASKMPDTRRL LRSMIFQVQR HQRPPQGLTV  240
QDLIDHLRKL LQQKRYLIVI DGLWETTSWD IVSSAFPEDT HCSRVLVTTD IQEVALECCD  300
YQSDGIFTME PLSTNDTREL LFNRAFGSNH ECSEQLKEVS EEVIKKCCGF PLATLCIAQV  360
LASDPDNSEL WHHIKESLSC DIRNNLTSED MLRGIIGLSY NSLPHHLKTC LLYFHMYPEG  420
YMFLKTDLVK QWAAEGFIGA VAGKNTSEIA ESYFDELVCR GFIQPNCINF SDGVMFYTVH  480
YTIFEVIRCK SMEGNFNTVI DYSEISTKLS AKVRRLSIRF SNAKYATKPE GITLSPVRSL  540
IFYGLVECLP SITEFESLRV LHLEFWGAHG DVLDLSGIDR LFQLRYLWVS TNVTVKLPTM  600
MTALQYLETL EIYAKVTTVP TDIVNLATLQ HLCLYGDINL PDGIAQMRSL RTLKSFDLSG  660
NSEDNVRSLG ELKNLHQLHL TCSVAPSDRL KRNLIALVSS LGKLGNLNSL VLAPGGSCTS  720
IYSDCSNSVS SVPVSLQILE LLPPICIFSR LPEWFGQLHN LRILKVVVTD LLRDDIDVII  780
GLQELTNLSL YVRKRTRESI IFKSATFPVL KYFKFRCGVL QLAFQAKAMP NLQKLKLEFN  840
AHRGDQYGGM LSGIEHLLNL REVAARILAG AGVKESDRMA AESAFIDTIS KKSGLPMINM  900
QWVDSFDEDL RRHHYPFSPH CSGTLGQCPA SPTSWQDESR SSSSHQPLPL IPGSSSHYRQ  960
WEKGMLLGSG TLGQVYEGFN SENGQICVIK EIKVSTDDSN SKECLRQLNQ EIVLLSQLSH  1020
PNIVQYYGSV LSNETLSVYL EYVSGISIHK MLQLGGPLGE ALLRNYTAQI LSGLAYLHGH  1080
NTVHSNIKVA NILVDFNGDT IKLADFGMAK LISQYTSMKS FKGSPSSMAP EVISNSNGYK  1140
FSVDLWSLGC TILEMATGKP PWGQYEGAAS IFKICNSQDI PDIPDHLSSE AKSFLKLCLQ  1200
RDPAARPTAA QLMDHPFAKD HPTSTDGNNI RISQFSDVPA STSHLDGIAI DPGKTLDVLR  1260
EASPDSNRNP TATVDITDLE ADFSLRMAGE GEDEATGTTT TFHVPTAAVG EELSAAFQPI  1320
PSDGYSWLKY GLKQAKGSEN QRSYYKCIFQ GCLVKKKVER SLPDGQIVEI VYKNAHNHAK  1380
PHVWARNSSA PAQLLQDGGG GDASDHTFGG MSGVTVATLE NPTVSVGNDD VVRVRSPRST  1440
GCSGLDEHEK DPKRMRKDID GEGISMAGSR TVREPRVVVQ TTSDVDFMDD GFRWRKYGKK  1500
SLRLGNPNPR SYYRCAMAGC PMRKHVERMS HDQRVVVTTY KGKHNHDAPA RGPSSLDRPP  1560
PAVANQSSGG AVQQQYARGF SGQGSVGVSS ASAQGADAGS SFEVSTLKDY VTGDAAFISE  1620
LR*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2clq_A	2e-45	965	1219	28	283	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
2clq_B	2e-45	965	1219	28	283	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
3vw6_A	2e-45	965	1219	14	269	Mitogen-activated protein kinase kinase kinase 5
3vw6_B	2e-45	965	1219	14	269	Mitogen-activated protein kinase kinase kinase 5
5uor_A	2e-45	965	1219	15	270	Mitogen-activated protein kinase kinase kinase 5
5uor_B	2e-45	965	1219	15	270	Mitogen-activated protein kinase kinase kinase 5
5uox_A	2e-45	965	1219	15	270	Mitogen-activated protein kinase kinase kinase 5
5uox_B	2e-45	965	1219	15	270	Mitogen-activated protein kinase kinase kinase 5
5up3_A	2e-45	965	1219	15	270	Mitogen-activated protein kinase kinase kinase 5
5up3_B	2e-45	965	1219	15	270	Mitogen-activated protein kinase kinase kinase 5
5v19_A	2e-45	965	1219	15	270	Mitogen-activated protein kinase kinase kinase 5
5v19_B	2e-45	965	1219	15	270	Mitogen-activated protein kinase kinase kinase 5
5v24_A	2e-45	965	1219	15	270	Mitogen-activated protein kinase kinase kinase 5
5v24_B	2e-45	965	1219	15	270	Mitogen-activated protein kinase kinase kinase 5
5vil_C	2e-45	965	1219	26	281	Mitogen-activated protein kinase kinase kinase 5
5vil_D	2e-45	965	1219	26	281	Mitogen-activated protein kinase kinase kinase 5
5vio_A	2e-45	965	1219	26	281	Mitogen-activated protein kinase kinase kinase 5
5vio_B	2e-45	965	1219	26	281	Mitogen-activated protein kinase kinase kinase 5
5vio_C	2e-45	965	1219	26	281	Mitogen-activated protein kinase kinase kinase 5
5vio_D	2e-45	965	1219	26	281	Mitogen-activated protein kinase kinase kinase 5
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Functional Description ? help Back to Top
Source	Description
UniProt	Disease resistance (R) protein that recognizes the AVR-Pia and AVR1-CO39 effector avirulence proteins from M.oryzae. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Contribution of RGA4 is required to recognize the effector avirulence proteins AVR-Pia and AVR1-CO39 from M.oryzae (PubMed:21251109, PubMed:23548743). Acts as a repressor of the RGA4-mediated cell death activation. Upon infection, recognition and binding of the AVR effectors relieve the RGA5-mediated repression and triggers the hypersensitive response (PubMed:25024433). Immune response triggered by the RGA4-RGA5 -mediated recognition of AVR1-CO39 confers resistance to X.oryzae pathovars (PubMed:27289079). {ECO:0000269\|PubMed:21251109, ECO:0000269\|PubMed:23548743, ECO:0000269\|PubMed:25024433, ECO:0000269\|PubMed:27289079}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_025827327.1	0.0	uncharacterized protein LOC112902452 isoform X1
Swissprot	F7J0N2	0.0	RGA5R_ORYSJ; Disease resistance protein RGA5
TrEMBL	A0A2S3IE34	0.0	A0A2S3IE34_9POAL; Uncharacterized protein
STRING	Pavir.Ha01176.1.p	0.0	(Panicum virgatum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP5435	6	6

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G38470.1	2e-63	WRKY DNA-binding protein 33

Link Out ? help Back to Top
Phytozome	Pahal.H01961.1

Publications ? help Back to Top
Okuyama Y, et al. A multifaceted genomics approach allows the isolation of the rice Pia-blast resistance gene consisting of two adjacent NBS-LRR protein genes. Plant J., 2011. 66(3): p. 467-79 [PMID:21251109] Cesari S, et al. The rice resistance protein pair RGA4/RGA5 recognizes the Magnaporthe oryzae effectors AVR-Pia and AVR1-CO39 by direct binding. Plant Cell, 2013. 25(4): p. 1463-81 [PMID:23548743] Césari S, et al. The NB-LRR proteins RGA4 and RGA5 interact functionally and physically to confer disease resistance. EMBO J., 2014. 33(17): p. 1941-59 [PMID:25024433] Cesari S,Bernoux M,Moncuquet P,Kroj T,Dodds PN A novel conserved mechanism for plant NLR protein pairs: the "integrated decoy" hypothesis. Front Plant Sci, 2014. 5: p. 606 [PMID:25506347] Huang D,Zhang Y,Zhao Y,Liu J,Peng YL Expression, purification, crystallization and preliminary X-ray diffraction analysis of the effector-interaction domain of the resistance protein RGA5-A from Oryza sativa L. japonica. Acta Crystallogr F Struct Biol Commun, 2015. 71(Pt 2): p. 171-4 [PMID:25664791] Hutin M, et al. Ectopic activation of the rice NLR heteropair RGA4/RGA5 confers resistance to bacterial blight and bacterial leaf streak diseases. Plant J., 2016. 88(1): p. 43-55 [PMID:27289079] Ortiz D, et al. Recognition of the Magnaporthe oryzae Effector AVR-Pia by the Decoy Domain of the Rice NLR Immune Receptor RGA5. Plant Cell, 2017. 29(1): p. 156-168 [PMID:28087830] Guo L, et al. Crystallization of the rice immune receptor RGA5A_S with the rice blast fungus effector AVR1-CO39 prepared via mixture and tandem strategies. Acta Crystallogr F Struct Biol Commun, 2018. 74(Pt 4): p. 262-267 [PMID:29633975] Guo L, et al. Specific recognition of two MAX effectors by integrated HMA domains in plant immune receptors involves distinct binding surfaces. Proc. Natl. Acad. Sci. U.S.A., 2018. 115(45): p. 11637-11642 [PMID:30355769]