PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pavir.8KG150700.1.p
Organism
Panicum virgatum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Panicinae; Panicum
Family WRKY
Protein Properties Length: 1309aa    MW: 145705 Da    PI: 6.4182
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pavir.8KG150700.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY64.12.4e-209981056359
                           -SS-EEEEE.EE--TT..-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                 WRKY    3 DgynWrKYG.qKevkg..sefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59  
                           D y+WrKYG +K+vk   se+ +sY++C +++Cpvkkkve s  d++++ei+Y+g+Hnh 
  Pavir.8KG150700.1.p  998 DCYSWRKYGlKKKVKAgvSENQQSYFKCGFPDCPVKKKVEISL-DGQTTEIMYKGSHNHA 1056
                           99*******66789965589***********************.***************7 PP
2WRKY841.5e-2611601217259
                           --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                 WRKY    2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59  
                           dDg++Wr YG+K+ + +++prsY+rC++agCp++k+ver+++d +vv++tY+g+Hnh+
  Pavir.8KG150700.1.p 1160 DDGFRWRMYGRKKLQRNPNPRSYFRCAMAGCPMRKRVERASHDLRVVVTTYTGKHNHD 1217
                           8********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF525402.03E-50148413IPR027417P-loop containing nucleoside triphosphate hydrolase
PfamPF009317.4E-52160441IPR002182NB-ARC
CDDcd000090.00109161253No hitNo description
PRINTSPR003646.3E-11176191No hitNo description
Gene3DG3DSA:3.40.50.3006.8E-13176305IPR027417P-loop containing nucleoside triphosphate hydrolase
PRINTSPR003646.3E-11249263No hitNo description
PRINTSPR003646.3E-11346360No hitNo description
SuperFamilySSF520581.22E-25495861IPR032675Leucine-rich repeat domain, L domain-like
Gene3DG3DSA:3.80.10.102.7E-19547843IPR032675Leucine-rich repeat domain, L domain-like
PRINTSPR003646.3E-11647663No hitNo description
SuperFamilySSF1182908.5E-159911058IPR003657WRKY domain
Gene3DG3DSA:2.20.25.801.3E-179951058IPR003657WRKY domain
SMARTSM007747.4E-179961057IPR003657WRKY domain
PROSITE profilePS5081111.7499981058IPR003657WRKY domain
PfamPF031063.4E-149981055IPR003657WRKY domain
Gene3DG3DSA:2.20.25.801.5E-2911451219IPR003657WRKY domain
SuperFamilySSF1182906.67E-2411521219IPR003657WRKY domain
PROSITE profilePS5081131.50211541219IPR003657WRKY domain
SMARTSM007741.0E-2811591218IPR003657WRKY domain
PfamPF031063.6E-2111601217IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043531Molecular FunctionADP binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 1309 aa     Download sequence    Send to blast
MEVQMSSSSL GAMGSLLGKL CSLLVSPEDQ LPEPLQLQKD KLKLLKQDLE EINKFLVNLS  60
WMEAPNMMVR HWMNEVRDLS YDIEDYIDKM HSDPNTDEVS SSGVDELSSL VNKAKDAHER  120
HNRYDLGRWA SDPRVVVDGQ GWIPRLNGEA TELVGIGDSK AQLIKQLNID VEQRIVVSIY  180
GPVGVGKTTL AKEVYRQIGG QFQCRAFVRA SKMPDTRRLL RSMIFQVQRH QRPPQGLTVQ  240
DLIDHLRKLL QQKRYLIVID GLWETTSWDI VSSAFPEDTH CSRVLVTTDI QDVALECCDY  300
QSDGIFTMEP LSRNDTRELL FNRAFGSNHE CSEQLKEVSE EIIKKCRGFS LATLCIARVL  360
ASKPDNSELW HHIKESLSCD IRNNLTSEDM LRGIIHLSYN SLPHHLKTCL LYFHMFPEGY  420
MFLKTDLLKQ WTAEGFISAA DGKATSKIAE SYFDELVYRG FIQPNRINFS DEVMFYTVHS  480
TIFEVIRCES MEGNFITVID YSEISTKLSA KVRRLSIRFS NAKYATKPEG ITLAPVRSLF  540
FYGLVECLPS ITEFESLRVL NLEVWGAHGD ELDLSGIDRL FQLRYLWVST NVTVKLPTMM  600
KALQYLETLE IYAKVTTVPT DIVNLATLQH LCLYGDINLP DGIAYLRSLR TLQSFDLSSN  660
SEDNVRSLGE LKNLHQLHLT CSGAPSDRLK RKLMALVSSL GKLGNLNSLV LAPGASCTSI  720
YSDCSNSVSC VPVSLQILEM LPPICIFSRL PEWFGQLRNL RILKVLVADL LGDDIDVIIG  780
LQELTNLSLY VRKPTRESIV FKSATFPVLK YFKFRCGVLH LAFQAKAMPN LQKLKLEFNA  840
HRGDQYSGML AGIEHLLNLR EVAARIGAGA GVEESDRMAA ESAFIDTISK NSGLPMINMQ  900
WVDSFDEEIS QFSDLQASTS HLDGIVIDDP GKTLDVFPEA SPYLKQNPTA TVDIIDLEAD  960
FSLRTTAGVG EEWISFHMPT AAVSEELSTA FQLISPYDCY SWRKYGLKKK VKAGVSENQQ  1020
SYFKCGFPDC PVKKKVEISL DGQTTEIMYK GSHNHAKPQN TRRNSSAAAQ LLQDSGAEAS  1080
DHTFAGLSGV TVAGLENPSA SVGNVVGMRS PHSSGLDEHE KDSKRLRKNS DGEGISLAGR  1140
RTVLEPRVVV QATSDVDIID DGFRWRMYGR KKLQRNPNPR SYFRCAMAGC PMRKRVERAS  1200
HDLRVVVTTY TGKHNHDAPA RGPSSLDLPP PAVANQSSGG AGQQQYAHGF SSGGSVGVSS  1260
ASAQGADGGS FEVSTPDAVE LDRANTTNWG QGGAQNEDMF FPGRVHSL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6s2p_N5e-381494846338NRC1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Pvr.232210.0root
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in leaves. {ECO:0000269|PubMed:21251109}.
Functional Description ? help Back to Top
Source Description
UniProtDisease resistance (R) protein that recognizes the AVR-Pia and AVR1-CO39 effector avirulence proteins from M.oryzae. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Contribution of RGA4 is required to recognize the effector avirulence proteins AVR-Pia and AVR1-CO39 from M.oryzae (PubMed:21251109, PubMed:23548743). Acts as a repressor of the RGA4-mediated cell death activation. Upon infection, recognition and binding of the AVR effectors relieve the RGA5-mediated repression and triggers the hypersensitive response (PubMed:25024433). Immune response triggered by the RGA4-RGA5 -mediated recognition of AVR1-CO39 confers resistance to X.oryzae pathovars (PubMed:27289079). {ECO:0000269|PubMed:21251109, ECO:0000269|PubMed:23548743, ECO:0000269|PubMed:25024433, ECO:0000269|PubMed:27289079}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPavir.8KG150700.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_025827327.10.0uncharacterized protein LOC112902452 isoform X1
SwissprotF7J0N20.0RGA5R_ORYSJ; Disease resistance protein RGA5
TrEMBLA0A2S3IE340.0A0A2S3IE34_9POAL; Uncharacterized protein
STRINGPavir.Ha01176.1.p0.0(Panicum virgatum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP543566
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G38470.11e-59WRKY DNA-binding protein 33
Publications ? help Back to Top
  1. Okuyama Y, et al.
    A multifaceted genomics approach allows the isolation of the rice Pia-blast resistance gene consisting of two adjacent NBS-LRR protein genes.
    Plant J., 2011. 66(3): p. 467-79
    [PMID:21251109]
  2. Cesari S, et al.
    The rice resistance protein pair RGA4/RGA5 recognizes the Magnaporthe oryzae effectors AVR-Pia and AVR1-CO39 by direct binding.
    Plant Cell, 2013. 25(4): p. 1463-81
    [PMID:23548743]
  3. Césari S, et al.
    The NB-LRR proteins RGA4 and RGA5 interact functionally and physically to confer disease resistance.
    EMBO J., 2014. 33(17): p. 1941-59
    [PMID:25024433]
  4. Cesari S,Bernoux M,Moncuquet P,Kroj T,Dodds PN
    A novel conserved mechanism for plant NLR protein pairs: the "integrated decoy" hypothesis.
    Front Plant Sci, 2014. 5: p. 606
    [PMID:25506347]
  5. Huang D,Zhang Y,Zhao Y,Liu J,Peng YL
    Expression, purification, crystallization and preliminary X-ray diffraction analysis of the effector-interaction domain of the resistance protein RGA5-A from Oryza sativa L. japonica.
    Acta Crystallogr F Struct Biol Commun, 2015. 71(Pt 2): p. 171-4
    [PMID:25664791]
  6. Hutin M, et al.
    Ectopic activation of the rice NLR heteropair RGA4/RGA5 confers resistance to bacterial blight and bacterial leaf streak diseases.
    Plant J., 2016. 88(1): p. 43-55
    [PMID:27289079]
  7. Ortiz D, et al.
    Recognition of the Magnaporthe oryzae Effector AVR-Pia by the Decoy Domain of the Rice NLR Immune Receptor RGA5.
    Plant Cell, 2017. 29(1): p. 156-168
    [PMID:28087830]
  8. Guo L, et al.
    Crystallization of the rice immune receptor RGA5A_S with the rice blast fungus effector AVR1-CO39 prepared via mixture and tandem strategies.
    Acta Crystallogr F Struct Biol Commun, 2018. 74(Pt 4): p. 262-267
    [PMID:29633975]
  9. Guo L, et al.
    Specific recognition of two MAX effectors by integrated HMA domains in plant immune receptors involves distinct binding surfaces.
    Proc. Natl. Acad. Sci. U.S.A., 2018. 115(45): p. 11637-11642
    [PMID:30355769]