PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pbr006167.1

Organism

Pyrus bretschneideri

Taxonomic ID

225117

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

C2H2

Protein Properties

Length: 536aa MW: 55683.2 Da PI: 8.8287

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr006167.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.6	2.3e-05	69	91	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Pbr006167.1 69 FVCEICSKGFQRDQNLQLHRRGH 91 89*******************88 PP
2	zf-C2H2	15.8	4e-05	145	167	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C+ C+k + +s+ k H++t+ Pbr006167.1 145 WQCERCSKKYAVQSDWKAHMKTC 167 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.03E-6	68	91	No hit	No description
Gene3D	G3DSA:3.30.160.60	6.5E-5	68	91	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Pfam	PF12874	0.034	69	91	No hit	No description
SMART	SM00355	0.036	69	91	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.887	69	91	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	71	91	IPR007087	Zinc finger, C2H2
SMART	SM00355	270	110	140	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	4.4E-5	133	166	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.03E-6	140	166	No hit	No description
SMART	SM00355	77	145	165	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 536 aa Download sequence Send to blast
MGELDNSSSP LPKVSTASGG EASLTSSARE AMTRSEPPQK KKRNLPGMPD PEADVITLSP 60 TTLLATNRFV CEICSKGFQR DQNLQLHRRG HNLPWKLKQR TSKEVRKRVY VCPETSCVHH 120 NPTRALGDLT GIKKHFCRKH GEKKWQCERC SKKYAVQSDW KAHMKTCGTR EYKCDCGTLF 180 SRRDSFITHR AFCDALAEES AKAQTLMVGS GGSTNPSSNP APSAKSAVVA SPPPPPHTPS 240 NTVVSPALSI QSSELPENPI GLSPPAPATT CLTTTAISTT SIATTSTGNC NNGTSVFASV 300 FAPSSASALM TQPPQASSPS SFTNQVSTLG RLDGSTTTSA INEPTSLSLS TSLYLSSTGF 360 SLFPTPDQQD HRDYAQPAAM SATALLQKAA QMGAAASNAS LLRGFGLSTT SSPSQESSTT 420 LQWNKKPESG GGAHVGAELG LQLLSTANVT QLNDLMMGPP SSFGGQPMTR DLLGLSIGSG 480 GGGGASTGGF SAFLNSFGGS GGAFNVAAPY GSGGAGGGSS QGESWEGAQD RKPNI*

Sequence ? help Back to Top

Protein Sequence Length: 536 aa Download sequence Send to blast

MGELDNSSSP LPKVSTASGG EASLTSSARE AMTRSEPPQK KKRNLPGMPD PEADVITLSP  60
TTLLATNRFV CEICSKGFQR DQNLQLHRRG HNLPWKLKQR TSKEVRKRVY VCPETSCVHH  120
NPTRALGDLT GIKKHFCRKH GEKKWQCERC SKKYAVQSDW KAHMKTCGTR EYKCDCGTLF  180
SRRDSFITHR AFCDALAEES AKAQTLMVGS GGSTNPSSNP APSAKSAVVA SPPPPPHTPS  240
NTVVSPALSI QSSELPENPI GLSPPAPATT CLTTTAISTT SIATTSTGNC NNGTSVFASV  300
FAPSSASALM TQPPQASSPS SFTNQVSTLG RLDGSTTTSA INEPTSLSLS TSLYLSSTGF  360
SLFPTPDQQD HRDYAQPAAM SATALLQKAA QMGAAASNAS LLRGFGLSTT SSPSQESSTT  420
LQWNKKPESG GGAHVGAELG LQLLSTANVT QLNDLMMGPP SSFGGQPMTR DLLGLSIGSG  480
GGGGASTGGF SAFLNSFGGS GGAFNVAAPY GSGGAGGGSS QGESWEGAQD RKPNI*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	7e-36	141	206	3	68	Zinc finger protein JACKDAW
5b3h_F	7e-36	141	206	3	68	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00403	DAP	Transfer from AT3G50700	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr006167.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009365587.1	0.0	PREDICTED: protein indeterminate-domain 2-like
Swissprot	Q9SCQ6	1e-136	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A498J6D5	0.0	A0A498J6D5_MALDO; Uncharacterized protein
STRING	XP_009365587.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2218	32	86

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G66730.1	1e-112	C2H2-like zinc finger protein

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]